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公开(公告)号:US20240417806A1
公开(公告)日:2024-12-19
申请号:US18742888
申请日:2024-06-13
Applicant: Drexel University , New York Institute of Technology
Inventor: Ming Xiao , Dong Zhang
IPC: C12Q1/6886 , C12Q1/683
Abstract: Described herein is a method of categorizing a cancer (such as into TEL+ cancer or ALT+ cancer). The method includes performing a global analysis of telomere lengths in cancer cells of the cancer, and determining the category of the cancer based on patterns of telomere lengths. Also described herein is a method of treating cancer based on the categorizing of the cancer.
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公开(公告)号:US11669612B2
公开(公告)日:2023-06-06
申请号:US16557416
申请日:2019-08-30
Applicant: THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY , NEW YORK INSTITUTE OF TECHNOLOGY, INC.
Inventor: Briland Hitaj , Giuseppe Ateniese , Fernando Perez-Cruz , Paolo Gasti
Abstract: Embodiments of the invention provide a system including a first logic module for receiving a data stream that includes at least one neural network configured to generate at least one first password sample based at least in part on at least a portion of the data stream. A second logic module can be operatively coupled to the first logic module to receive the first password sample and at least one input dataset including a second password sample. The system can perform calculations to distinguish between at least one password of the first password sample and at least one password of the second password sample. Further, the system can iteratively learn and produce a feedback dataset based on the calculations, where the feedback dataset is configured to be provided to the first logic module.
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3.
公开(公告)号:US20190380611A1
公开(公告)日:2019-12-19
申请号:US16456802
申请日:2019-06-28
Applicant: NEW YORK INSTITUTE OF TECHNOLOGY
Inventor: Youhua ZHANG
Abstract: The invention relates to a catheter useful in recording His electrogram alternans. The catheter includes a catheter probe containing at least one row of receiving poles positioned at an edge of the catheter probe, equidistantly spaced from each other.
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公开(公告)号:US09968507B2
公开(公告)日:2018-05-15
申请号:US15036985
申请日:2014-11-12
Applicant: New York Institute of Technology
Inventor: Ely Rabin , Ziqian Dong
IPC: B62B5/04 , A61H3/04 , B60L3/00 , B60L15/20 , B60L15/30 , B62D51/04 , G01S15/93 , G01S17/93 , A61H3/00
CPC classification number: A61H3/04 , A61H2003/002 , A61H2003/007 , A61H2003/043 , A61H2003/046 , A61H2201/0176 , A61H2201/50 , A61H2201/501 , A61H2201/5028 , A61H2201/5064 , A61H2201/5097 , B60L3/0015 , B60L15/2009 , B60L15/2036 , B60L15/30 , B60L2200/24 , B60L2240/12 , B60L2240/423 , B62D51/04 , G01S15/93 , G01S17/93 , Y02T10/7258
Abstract: A motorized walker is provided that can enable users to walk without being slowed by the walker and without needing to exert themselves to push the walker forward. The motorized walker provides additional haptic speed cues to inform the user's posture and locomotion control to prevent falling.
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5.
公开(公告)号:US11317844B2
公开(公告)日:2022-05-03
申请号:US16456802
申请日:2019-06-28
Applicant: NEW YORK INSTITUTE OF TECHNOLOGY
Inventor: Youhua Zhang
Abstract: The invention relates to a catheter useful in recording His electrogram alternans. The catheter includes a catheter probe containing at least one row of receiving poles positioned at an edge of the catheter probe, equidistantly spaced from each other.
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公开(公告)号:US20210180056A1
公开(公告)日:2021-06-17
申请号:US16074313
申请日:2017-02-15
Applicant: New York Institute of Technology
Inventor: Dong ZHANG
IPC: C12N15/113 , C07K16/00
Abstract: The method involves an approach of inhibiting replication of dysfunctional cells which adopt alternative lengthening of telomeres, or “ALT.” The methodology involves inhibition of Fanconi anemia complementation group M (FANCM), and one or both of breast cancer 1 (BRCA1) and Bloom syndrome protein (BLM). These molecules are the keys to the elimination of replication stress caused by ALT. In other words, they permit the dysfunctional cells to proliferate. Inhibition of these molecules inhibits proliferation.
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7.
公开(公告)号:US10383538B2
公开(公告)日:2019-08-20
申请号:US14848901
申请日:2015-09-09
Applicant: NEW YORK INSTITUTE OF TECHNOLOGY
Inventor: Youhua Zhang
Abstract: The invention relates to a catheter useful in recording His electrogram alternans. The catheter includes a catheter probe containing at least one row of receiving poles positioned at an edge of the catheter probe, equidistantly spaced from each other.
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8.
公开(公告)号:US20240181012A1
公开(公告)日:2024-06-06
申请号:US18386081
申请日:2023-11-01
Applicant: New York Institute of Technology
Inventor: Gonzalo Hugo OTAZU ALDANA
Abstract: Methods and formulations for treating autism with neurotensin R1 agonists without causing significant lethargy in a subject.
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公开(公告)号:US20220220552A1
公开(公告)日:2022-07-14
申请号:US17235621
申请日:2021-04-20
Applicant: New York Institute of Technology
Inventor: Shenglong ZHANG , Xiaohong YUAN
IPC: C12Q1/6869 , C12Q1/6806 , G16B30/10
Abstract: The present disclosure provides methods for direct sequencing of RNA, including but not limited to any coding RNA and non-coding RNA such as tRNA, rRNA, mRNA, short or long non-coding RNA as well as any of their modified forms/versions, without the need for generation of a cDNA intermediate and/or intensive sample preparation.
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公开(公告)号:US20210198734A1
公开(公告)日:2021-07-01
申请号:US17058167
申请日:2019-05-24
Applicant: New York Institute of Technology
Inventor: Shenglong Zhang , Ning Zhang
IPC: C12Q1/6872 , C12N15/10
Abstract: The present disclosure relates generally to novel methods for nucleic acid sequencing. Specifically, the invention relates to a liquid chromatography-mass-spectrometry (LC-MS) based technique for direct sequencing of RNA without cDNA. The technique allows one to simultaneously read an RNA sequence with single nucleotide resolution while determining the presence, type and location of a wide spectrum of RNA modifications.
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