Inhalable therapeutics
    1.
    发明授权

    公开(公告)号:US12251471B2

    公开(公告)日:2025-03-18

    申请号:US17872830

    申请日:2022-07-25

    Abstract: Disclosed herein are embodiments of a nanoparticle composition suitable for delivering a therapeutic agent to a subject by nebulization. The nanoparticle comprises an ionizable lipid, cholesterol or a derivative thereof, a structural lipid, and a PEG lipid. The nanoparticle may partially or completely encapsulate a therapeutic agent, and may be nebulized for administration, such as by inhalation. In some embodiments, the therapeutic agent is mRNA.

    COMPOUNDS HAVING A THORTVEITITE-RELATED STRUCTURE AND METHODS FOR MAKING AND USING

    公开(公告)号:US20250051179A1

    公开(公告)日:2025-02-13

    申请号:US18929145

    申请日:2024-10-28

    Abstract: Novel compounds having a thortveitite-related structure are disclosed. The compounds may be colored and may be useful as pigments. The compounds are durable with respect to an acid stability test that indicates that the pigments will not substantially change color when exposed to weak acids, such as rain. The compounds disclosed herein typically inexpensive to synthesize from earth-abundant, environmentally-friendly elements or minerals, and therefore are advantageous over existing pigments in the art.

    VEHICLE ENERGY ROUTING
    3.
    发明申请

    公开(公告)号:US20250020478A1

    公开(公告)日:2025-01-16

    申请号:US18349569

    申请日:2023-07-10

    Inventor: David Hamilton

    Abstract: Briefly, embodiments, such as estimating energy utilization based at least in part on estimated regenerative energy production to select one or more preferred routes for an electric vehicle out of a network of routes, for example, are described.

    AUTONOMOUS ORGANISMS FOR SYNTHESIS OF PERMANENTLY PHOSPHORYLATED PROTEINS

    公开(公告)号:US20240391961A1

    公开(公告)日:2024-11-28

    申请号:US18686249

    申请日:2022-08-25

    Abstract: Embodiments of the present disclosure provide compositions and methods for biosynthesizing a stable, functional mimic of phosphoserine. The compositions and methods described herein genetically program a host cell to express a biosynthetic pathway that can synthesize the amino acid, 2-amino-4-phosphobobutyric acid, that is a non-hydrolyzable phosphoserine (nhpSer) because it contains a carbon-phosphorus, e.g., phosphonate, bond. In one embodiment the genetically programed cells express the enzymes of a pathway from a Streptomyces bacterium. In some embodiments, nhpSer is translationally incorporated into protein of interest at one or more programmed UAG amber codons using Genetic Code Expansion (GCE) technology.

    SCALING-FRIENDLY, ANALOG CORRELATORS USING CHARGE-BASED MARGIN PROPAGATION

    公开(公告)号:US20240380408A9

    公开(公告)日:2024-11-14

    申请号:US18485939

    申请日:2023-10-12

    Abstract: A non-multiply-accumulate (non-MAC) charge-based analog correlator system including a sampler circuit block, an operand generation circuit block, and a margin propagation (MP) correlation computation circuit block is disclosed. The sampler circuit block is configured to sample a plurality of input analog signals. The operand generation circuit block is configured to generate operands based on the sampled plurality of input analog signals, and the margin propagation (MP) correlation computation circuit block is configured to generate correlated output signals based on the operands and using calculations in a charge domain.

    9.
    植物专利
    有权

    公开(公告)号:USPP35894P2

    公开(公告)日:2024-07-02

    申请号:US18214058

    申请日:2023-06-26

    Abstract: A new Vaccinium ovatum plant distinguished by its upright and vigorous, yet compact growth habit, dense branching, and DNA content (tetraploid).

    10.
    植物专利
    有权

    公开(公告)号:USPP35866P2

    公开(公告)日:2024-06-11

    申请号:US18113485

    申请日:2023-02-23

    Abstract: A new and distinct Hibiscus plant cultivar named ‘ORSTHIB5X1’ is disclosed, characterized by its growth habit and form, deep green foliage that is resistant to chlorosis, seedlessness, and pentaploid chromosome complement.

Patent Agency Ranking