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    SOLUBILISATION OF MEMBRANE PROTEINS
    2.
    发明申请
    SOLUBILISATION OF MEMBRANE PROTEINS 有权
    膜蛋白的溶解

    公开(公告)号：US20120142861A1

    公开(公告)日：2012-06-07

    申请号：US13382432

    申请日：2010-07-08

    Applicant: Timothy Dafforn ,  Michael Overduin ,  Timothy Knowles

    Inventor： Timothy Dafforn ,  Michael Overduin ,  Timothy Knowles

    IPC: C08L33/02

    CPC classification number: G01N33/6803

    Abstract: A method is provided for solubilising a membrane protein. The method is applied to cellular material comprising the membrane protein and an associated membrane lipid. A copolymer of styrene and maleic acid, wherein the styrene:maleic acid ratio is between 1:2 and 10:1, is mixed with the cellular material to cause the copolymer, lipid and protein to form soluble macromolecular assemblies.

    Abstract translation: 提供了用于增溶膜蛋白的方法。 该方法应用于包含膜蛋白和相关膜脂质的细胞材料。 苯乙烯和马来酸的共聚物，其中苯乙烯：马来酸比为1:2至10:1，与多孔材料混合，使共聚物，脂质和蛋白质形成可溶的大分子组装体。

    Solubilisation of membrane proteins
    4.
    发明授权
    Solubilisation of membrane proteins 有权
    膜蛋白的溶解

    公开(公告)号：US08754168B2

    公开(公告)日：2014-06-17

    申请号：US13382432

    申请日：2010-07-08

    Applicant: Timothy Dafforn ,  Michael Overduin ,  Timothy Knowles

    Inventor： Timothy Dafforn ,  Michael Overduin ,  Timothy Knowles

    IPC: C08G63/91

    CPC classification number: G01N33/6803

    Abstract: A method is provided for solubilising a membrane protein. The method is applied to cellular material comprising the membrane protein and an associated membrane lipid. A copolymer of styrene and maleic acid, wherein the styrene:maleic acid ratio is between 1:2 and 10:1, is mixed with the cellular material to cause the copolymer, lipid and protein to form soluble macromolecular assemblies.

    Abstract translation: 提供了用于增溶膜蛋白的方法。 该方法应用于包含膜蛋白和相关膜脂质的细胞材料。 苯乙烯和马来酸的共聚物，其中苯乙烯：马来酸比为1:2至10:1，与多孔材料混合，使共聚物，脂质和蛋白质形成可溶的大分子组装体。

    Fiber adhesive material
    6.
    发明申请
    Fiber adhesive material 审中-公开
    纤维粘合剂材料

    公开(公告)号：US20060213599A1

    公开(公告)日：2006-09-28

    申请号：US11441472

    申请日：2006-05-26

    Applicant: Timothy Knowles ,  Christopher Seaman

    Inventor： Timothy Knowles ,  Christopher Seaman

    IPC: B32B37/00

    CPC classification number: C09J7/00 ,  B08B1/00 ,  B08B7/0028 ,  B82Y10/00 ,  B82Y30/00 ,  C09J2201/626 ,  F28F3/022 ,  H01L23/36 ,  H01L23/373 ,  H01L23/4275 ,  H01L2924/0002 ,  Y10S428/903 ,  Y10T428/23957 ,  Y10T428/23993 ,  Y10T428/24132 ,  Y10T428/2913 ,  Y10T428/292 ,  Y10T428/2935 ,  Y10T428/294 ,  Y10T428/298 ,  Y10T442/603 ,  Y10T442/608 ,  Y10T442/614 ,  H01L2924/00

    Abstract: A fiber velvet comprising nano-size fibers or nanofibrils attached to micro-size fibers is disclosed. Methods of manufacturing the velvet as well as various uses of the velvet are also described. For example, the fiber velvet can be used as a thermal interface or as an adhesive material. The nanofibrils may be attached to a flat base or membrane, or may be attached to the tip portions of the micro-size or larger diameter fibers. Various attributes of the micro-size fibers and of the nano-size fibers, for example, geometry (e.g. size, length, packing density) material type (e.g. carbon, metal, polymer, or ceramic) and properties (e.g. conductivity, modulus, surface energy, dielectric constant, surface roughness) can be selected depending on the desired attributes of the fiber velvet. The nanofibrils have a diameter of less than about 1 micron, and may advantageously be formed from single walled and/or multi-walled carbon nanotubes.

    Abstract translation: 公开了包含连接到微尺寸纤维的纳米尺寸纤维或纳米纤丝的纤维天鹅绒。 还描述了天鹅绒的制造方法以及天鹅绒的各种用途。 例如，纤维天鹅绒可以用作热界面或粘合剂材料。 纳米纤丝可以连接到平坦的基底或膜上，或者可以附着到微尺寸或更大直径纤维的末端部分。 微尺寸纤维和纳米尺寸纤维的各种属性，例如几何形状（例如尺寸，长度，包装密度）材料类型（例如碳，金属，聚合物或陶瓷）和性质（例如导电率，模量， 表面能，介电常数，表面粗糙度）可以根据纤维天鹅绒的期望属性来选择。 纳米原纤维具有小于约1微米的直径，并且可以有利地由单壁和/或多壁碳纳米管形成。

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