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1.Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas 失效
Title translation: 使用喹啉基,异喹啉基或吡啶基脲来抑制RAF激酶公开(公告)号:US20060019990A1
公开(公告)日:2006-01-26
申请号:US11158048
申请日:2005-06-22
Applicant: Jacques Dumas , Bernd Riedl , Uday Khire , Robert Sibley , Holia Hatoum-Mokdad , Mary-Katherine Monahan , David Gunn , Timotthy Lowinger , William Scott , Roger Smith , Jill Wood
Inventor: Jacques Dumas , Bernd Riedl , Uday Khire , Robert Sibley , Holia Hatoum-Mokdad , Mary-Katherine Monahan , David Gunn , Timotthy Lowinger , William Scott , Roger Smith , Jill Wood
IPC: A61K31/4709 , A61K31/444 , C07D401/02
CPC classification number: C07D213/40
Abstract: The invention relates to a group of quinolyl, isoquinolyl and pyridyl ureas, their the use in treating raf mediated diseases, and pharmaceutical compositions which contain these ureas for use in such therapy.
Abstract translation: 本发明涉及一组喹啉基,异喹啉基和吡啶基脲,它们在治疗raf介导的疾病中的用途,以及含有用于这种治疗的这些尿素的药物组合物。