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公开(公告)号：US12269902B2
公开(公告)日：2025-04-08
申请号：US18240295
申请日：2023-08-30
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： Richard Béliveau , Borhane Annabi , Michel Demeule , Alain Larocque , Jean-Christophe Currie , Cyndia Charfi
Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer. For example, the compounds can comprise compounds of formula (SEQ ID NO: 1) X1X2X3X4X5GVX6AKAGVX7NX8FKSESY (I) (SEQ ID NO: 2) (X9)nGVX10AKAGVX11NX12FKSESY (II) (SEQ ID NO: 3) YKX13LRRX14APRWDX15PLRDPALRX16X17L (III) (SEQ ID NO: 4) YKX18LRR(X19)nPLRDPALRX20X21L (IV) (SEQ ID NO: 5) IKLSGGVQAKAGVINMDKSESM (V) (SEQ ID NO: 6) IKLSGGVQAKAGVINMFKSESY (VI) (SEQ ID NO: 7) IKLSGGVQAKAGVINMFKSESYK (VII) (SEQ ID NO: 8) GVQAKAGVINMFKSESY (VIII) (SEQ ID NO: 9) GVRAKAGVRNMFKSESY (IX) (SEQ ID NO: 10) GVRAKAGVRN(Nle)FKSESY (X) (SEQ ID NO: 11) YKSLRRKAPRWDAPLRDPALRQLL (XI) (SEQ ID NO: 12) YKSLRRKAPRWDAYLRDPALRQLL (XII) (SEQ ID NO: 13) YKSLRRKAPRWDAYLRDPALRPLL (XIII) wherein X1 to X21 and n can have various different values and wherein at least one protecting group and/or at least one labelling agent is optionally connected to said peptide compound at an N- and/or C-terminal end.
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公开(公告)号：US11081761B2
公开(公告)日：2021-08-03
申请号：US16318878
申请日：2017-07-21
Applicant: HYDRO-QUÉBEC , Transfert Plus, S.E.C.
Inventor： Nicolas Delaporte , Diby Benjamin Ossonon , Karim Zaghib , Daniel Belanger
IPC: H01M50/46 , H01M4/04 , H01M4/62 , H01M10/0525 , H01M4/13 , H01M4/1391 , H01M4/139 , H01M4/1397 , H01M50/403 , H01M50/411 , H01M10/052 , H01M4/131 , H01M4/136
Abstract: This application describes a process for the preparation of flexible electrode-separator elements or assemblies, which includes the application of an electrode material on the separator. The electrode material comprises graphene, for instance produced by graphite exfoliation. The electrode-separator elements obtained by the process as well as their use in electrochemical cells are also described.
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公开(公告)号：US20130287816A1
公开(公告)日：2013-10-31
申请号：US13872503
申请日：2013-04-29
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： DENIS ARCHAMBAULT , ELODIE ROQUES
IPC: C07K14/00
CPC classification number: C07K14/001 , C07K14/30
Abstract: Immunogenic compositions comprising a p97 adhesin adjuvant polypeptide, or a nucleic acid encoding said p97 adhesin adjuvant polypeptide, and a heterologous antigen are disclosed. Uses of the p97 adhesin adjuvant polypeptide or nucleic acid, or immunogenic compositions comprising same, for inducing an immune response against a heterologous antigen in a subject are also disclosed.
Abstract translation: 公开了包含p97粘附素佐剂多肽或编码所述p97粘附素佐剂多肽的核酸和异源抗原的免疫原性组合物。 还公开了p97粘附素佐剂多肽或核酸或包含其的免疫原性组合物用于诱导受试者中异源抗原的免疫应答的用途。
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4.发明公开公开(公告)号：US20240199695A1
公开(公告)日：2024-06-20
申请号：US18240295
申请日：2023-08-30
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： Richard BÉLIVEAU , Borhane ANNABI , Michel DEMEULE , Alain LAROCQUE , Jean-Christophe CURRIE , Cyndia CHARFI
CPC classification number: C07K7/08 , A61K31/337 , A61K47/64 , A61P35/00 , C07K1/061 , C07K14/001 , A61K38/00
Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer. For example, the compounds can comprise compounds of formula
(SEQ ID NO: 1)
X1X2X3X4X5GVX6AKAGVX7NX8FKSESY
(I)
(SEQ ID NO: 2)
(X9)nGVX10AKAGVX11NX12FKSESY
(II)
(SEQ ID NO: 3)
YKX13LRRX14APRWDX15PLRDPALRX16X17L
(III)
(SEQ ID NO: 4)
YKX18LRR(X19)nPLRDPALRX20X21L
(IV)
(SEQ ID NO: 5)
IKLSGGVQAKAGVINMDKSESM
(V)
(SEQ ID NO: 6)
IKLSGGVQAKAGVINMFKSESY
(VI)
(SEQ ID NO: 7)
IKLSGGVQAKAGVINMFKSESYK
(VII)
(SEQ ID NO: 8)
GVQAKAGVINMFKSESY
(VIII)
(SEQ ID NO: 9)
GVRAKAGVRNMFKSESY
(IX)
(SEQ ID NO: 10)
GVRAKAGVRN(Nle)FKSESY
(X)
(SEQ ID NO: 11)
YKSLRRKAPRWDAPLRDPALRQLL
(XI)
(SEQ ID NO: 12)
YKSLRRKAPRWDAYLRDPALRQLL
(XII)
(SEQ ID NO: 13)
YKSLRRKAPRWDAYLRDPALRPLL
(XIII)
wherein X1 to X21 and n can have various different values
and wherein at least one protecting group and/or at least one labelling agent is optionally connected to said peptide compound at an N- and/or C-terminal end.-
公开(公告)号：US20220356209A1
公开(公告)日：2022-11-10
申请号：US17239544
申请日：2021-04-23
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： Richard BÉLIVEAU , Borhane ANNABI , Michel DEMEULE , Alain LAROCQUE , Jean-Christophe CURRIE , Cyndia CHARFI
Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer. For example, the compounds can comprise compounds of formula X1X2X3X4X5GVX6AKAGVX7NX8FKSESY
(I)
(SEQ ID NO: 1) (X9)nGVX10AKAGVX11NX12FKSESY
(II)
(SEQ ID NO: 2) YKX13LRRX14APRWDX15PLRDPALRX16X17L
(III)
(SEQ ID NO: 3) YKX18LRR(X19)nPLRDPALRX20X21L
(IV)
(SEQ ID NO: 4) IKLSGGVQAKAGVINMDKSESM
(V)
(SEQ ID NO: 5) IKLSGGVQAKAGVINMFKSESY
(VI)
(SEQ ID NO: 6) IKLSGGVQAKAGVINMFKSESYK
(VII)
(SEQ ID NO: 7) GVQAKAGVINMFKSESY
(VIII)
(SEQ ID NO: 8) GVRAKAGVRNMFKSESY
(IX)
(SEQ ID NO: 9) GVRAKAGVRN(Nle)FKSESY
(X)
(SEQ ID NO: 10) YKSLRRKAPRWDAPLRDPALRQLL
(XI)
(SEQ ID NO: 11) YKSLRRKAPRWDAYLRDPALRQLL
(XII)
(SEQ ID NO: 12) YKSLRRKAPRWDAYLRDPALRPLL
(XIII)
(SEQ ID NO: 13) wherein X1 to X21 and n can have various different values and wherein at least one protecting group and/or at least one labelling agent is optionally connected to said peptide compound at an N- and/or C-terminal end.-
Patent Agency Ranking
6.发明申请公开(公告)号：US20220000971A1
公开(公告)日：2022-01-06
申请号：US17270787
申请日：2019-08-26
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： Richard BÉLIVEAU , Borhane ANNABI , Michel DEMEULE , Alain LAROCQUE , Jean-Christophe CURRIE , Alain ZGHEIB
Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treatment of cancer or aggressive cancer. For example, the compounds can comprise compounds of formula X1X2X3X4X5GVX6AKAGVX7NX8FKSESY (I) (SEQ ID NO: 1) (X9)nGVX10AKAGVX11NX12FKSESY (II) (SEQ ID NO: 2) YKX13LRRX14APRWDX15PLRDPALRX16X17L (III) (SEQ ID NO: 3) YKX18LRR(X19)nPLRDPALRX20X21L (IV) (SEQ ID NO: 4) IKLSGGVQAKAGVINMDKSESM (V) (SEQ ID NO: 5) IKLSGGVQAKAGVINMFKSESY (VI) (SEQ ID NO: 6) IKLSGGVQAKAGVINMFKSESYK (VII) (SEQ ID NO: 7) GVQAKAGVINMFKSESY (VIII) (SEQ ID NO: 8) GVRAKAGVRNMFKSESY (IX) (SEQ ID NO: 9) GVRAKAGVRN(Nle)FKSESY (X) (SEQ ID NO: 10) YKSLRRKAPRWDAPLRDPALRQLL (XI) (SEQ ID NO: 11) YKSLRRKAPRWDAYLRDPALRQLL (XII) (SEQ ID NO: 12) YKSLRRKAPRWDAYLRDPALRPLL (XIII) (SEQ ID NO: 13) wherein X1 to X21 and n can have various different values and wherein at least one protecting group and/or at least one labelling agent is optionally connected to said peptide compound at an N- and/or C-terminal end, for use in inhibiting vasculogenic mimicry and/or for treating a cancer.
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公开(公告)号：US09028828B2
公开(公告)日：2015-05-12
申请号：US13872503
申请日：2013-04-29
Applicant: Transfert Plus, S.E.C.
Inventor： Denis Archambault , Elodie Roques
CPC classification number: C07K14/001 , C07K14/30
Abstract: Immunogenic compositions comprising a p97 adhesin adjuvant polypeptide, or a nucleic acid encoding said p97 adhesin adjuvant polypeptide, and a heterologous antigen are disclosed. Uses of the p97 adhesin adjuvant polypeptide or nucleic acid, or immunogenic compositions comprising same, for inducing an immune response against a heterologous antigen in a subject are also disclosed.
Abstract translation: 公开了包含p97粘附素佐剂多肽或编码所述p97粘附素佐剂多肽的核酸和异源抗原的免疫原性组合物。 还公开了p97粘附素佐剂多肽或核酸或包含其的免疫原性组合物用于诱导受试者中异源抗原的免疫应答的用途。
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公开(公告)号：US11034727B2
公开(公告)日：2021-06-15
申请号：US15778626
申请日：2016-11-24
Applicant: TRANSFERT PLUS, S.E.C.
Inventor： Richard Béliveau , Borhane Annabi , Michel Demeule , Alain Larocque , Jean-Christophe Currie , Cyndia Charfi
Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating cancer and increasing cellular internalization of said peptide compounds. The peptide compounds are selected from the following group consisting of; GVRAKAGVRNMFKSESY as set forth in SEQ ID NO: 9; GVRAKAGVRN(Nle)FKSESY as set forth in SEQ ID NO: 10; and YKSLRRKAPRWDAPLRDPALRQLL as set forth in SEQ ID NO: 11; and wherein at least one protecting group and/or at least one labelling agent is connected to said peptide compound.
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公开(公告)号：US10811736B2
公开(公告)日：2020-10-20
申请号：US16318826
申请日：2017-07-21
Applicant: HYDRO-QUÉBEC , TRANSFERT PLUS, S.E.C.
Inventor： Nicolas Delaporte , Diby Benjamin Ossonon , Karim Zaghib , Daniel Belanger
Abstract: A process for recycling an electrode material comprising graphene and an electrochemically active material is described. The process comprises a step of adding, in any order, water and a non-miscible solvent to the electrode material, thereby forming a biphasic system comprising an organic phase and an aqueous phase; and a step of separating and filtering the organic phase to recover graphene. The process optionally comprises additional steps of washing, drying, and/or thermally treating. Also described are electrodes including the recycled graphene, as well as the electrochemical cells and their uses.
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公开(公告)号：US20190288260A1
公开(公告)日：2019-09-19
申请号：US16318878
申请日：2017-07-21
Applicant: HYDRO-QUÉBEC , Transfert Plus, S.E.C.
Inventor： Nicolas DELAPORTE , Diby Benjamin OSSONON , Karim ZAGHIB , Daniel BELANGER
IPC: H01M2/16 , H01M2/14 , H01M4/62 , H01M10/0525 , H01M4/04
Abstract: This application describes a process for the preparation of flexible electrode-separator elements or assemblies, which includes the application of an electrode material on the separator. The electrode material comprises graphene, for instance produced by graphite exfoliation. The electrode-separator elements obtained by the process as well as their use in electrochemical cells are also described.
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