公开(公告)号：US20250019545A1

公开(公告)日：2025-01-16

申请号：US18771291

申请日：2024-07-12

Applicant: DOMINGOS DA SILVA TEIXEIRA, S.A. ,  UNIVERSIDADE DO MINHO ,  CVR - CENTRO PARA A VALORIZAÇÃO DE RESÍDUOS

Inventor： MAFALDA MARGARIDA MESQUITA RODRIGUES ,  JACINTO MANUEL CASTRO DE OLIVEIRA ,  JOSÉ MANUEL NOGUEIRA DA COSTA ,  HUGO MANUEL RIBEIRO DIAS DA SILVA ,  JOEL RICARDO MARTINS DE OLIVEIRA ,  CAROLINE FERNANDES NUNES DE MOURA ,  CARLOS DANIEL ALEIXO LOUREIRO ,  LUCAS PEREIRA DO NASCIMENTO

IPC: C08L95/00 ,  C04B26/26 ,  C08K3/08 ,  C08K3/34

Abstract: The present disclosure relates to an asphalt concrete mixture comprising: 50% to 75% (w/w) of steel slag aggregates, wherein the size of the steel slag aggregates is up to 20 mm, measured by sieving; 15% to 30% (w/w) of reclaimed asphalt, wherein the size of the of reclaimed asphalt is up to 14 mm, measured by sieving; 10% to 20% (w/w) of natural stone aggregates and/or filler; and 2% to 4% (w/w) of virgin bitumen. Infrastructures comprising the described asphalt concrete mixture are also disclosed.

公开(公告)号：US12115242B2

公开(公告)日：2024-10-15

申请号：US18334287

申请日：2023-06-13

Applicant: Universidade do Minho

Inventor： Artur Manuel Cavaco Paulo ,  Celia Freitas Da Cruz ,  Margarida Maria Macedo Francesko Fernandes

IPC: A61K8/64 ,  A61Q5/00 ,  A61Q5/04 ,  A61Q5/06

CPC classification number: A61K8/64 ,  A61K8/645 ,  A61Q5/002 ,  A61Q5/04 ,  A61Q5/06 ,  A61Q5/065 ,  A61K2800/30

Abstract: The current application discloses a composition that comprises at least one peptide with a sequence length of 6-12 amino acids, where 2-5 of those amino acids are cysteines for the treatment and cosmetics of animal hair, in preference human hair. There are several hair styling methods that involve breakage and reestablishment of disulfide bonds, allowing relaxation and straightening of the hair. However, the most effective methods currently used to modulate hair contain harmful chemicals. Thus, there is a constant demand for formulations that efficiently model the hair fiber without damage. Thus, the present invention aims to provide a composition for treatment of the hair, including animal and human hair, without the use of chemicals harmful to the hair fiber and consumer health and uses of said compositions in shampoo, lotion, serum, cream, conditioner, foam, elixir, oil, aerosol or mask.

公开(公告)号：US20240115481A1

公开(公告)日：2024-04-11

申请号：US18520428

申请日：2023-11-27

Applicant: Universidade do Minho

Inventor： Artur Manuel CAVACO PAULO ,  Filipa Daniela GOMES GONÇALVES ,  Artur Jorge ARAÚJO MAGALHÃES RIBEIRO ,  Carla Manuela PEREIRA MARINHO DA SILVA

IPC: A61K8/64 ,  A61K8/11 ,  A61Q15/00

CPC classification number: A61K8/64 ,  A61K8/11 ,  A61Q15/00

Abstract: The present disclosure relates to a release composition comprising a protein and an active agent, wherein the active agent is released when in presence of an electrolyte solution. A kit and an article comprising the release composition of the present-subject matter are also encompassed.

公开(公告)号：US20240092793A1

公开(公告)日：2024-03-21

申请号：US17560859

申请日：2020-06-29

Applicant: UNIVERSIDADE DO MINHO

Inventor： Marta Sílvia Freitas Da Costa ,  Maria De Fátima Monginho Baltazar ,  Maria Fernanda De Jesus Rego Paiva Proença ,  Patrícia Maciel ,  Olívia Alexandra Elias Pontes

IPC: C07D491/052 ,  C07D519/00

CPC classification number: C07D491/052 ,  C07D519/00

Abstract: The present disclosure relates to a compound or a pharmaceutically acceptable salt, hydrate, solvate, N-oxide, stereoisomer, diastereoisomer, enantiomer, atropisomer, dimer, or polymorph for use in medicine comprising the following formula:






wherein
R1, R2 and R3 are independently selected from each other;
R1 is selected from an aryl, or heterocyclic ring;
R2 is selected from a H, alkyl, aryl, alcoxyl, halogen, hydroxyl, amine, carbonyl, or heterocyclic ring;
R3 is selected from a H, or

公开(公告)号：US20230338263A1

公开(公告)日：2023-10-26

申请号：US18194372

申请日：2023-03-31

Applicant: Universidade do Minho

Inventor： Artur Manuel CAVACO PAULO ,  Celia FREITAS DA CRUZ ,  Margarida Maria MACEDO FRANCESKO FERNANDES

IPC: A61K8/64 ,  A61Q5/00 ,  A61Q5/04 ,  A61Q5/06

CPC classification number: A61K8/64 ,  A61Q5/002 ,  A61K8/645 ,  A61Q5/04 ,  A61Q5/065 ,  A61Q5/06 ,  A61K2800/30

Abstract: The current application discloses a composition that comprises at least one peptide with a sequence length of 6-12 amino acids, where 2-5 of those amino acids are cysteines for the treatment and cosmetics of animal hair, in preference human hair. There are several hair styling methods that involve breakage and reestablishment of disulfide bonds, allowing relaxation and straightening of the hair. However, the most effective methods currently used to modulate hair contain harmful chemicals. Thus there is a constant demand for formulations that efficiently model the hair fiber without damage. Thus, the present invention aims to provide a composition for treatment of the hair, including animal and human hair, without the use of chemicals harmful to the hair fiber and consumer health and uses of said compositions in shampoo, lotion, serum, cream, conditioner, foam, elixir, oil, aerosol or mask.

公开(公告)号：US11435284B2

公开(公告)日：2022-09-06

申请号：US16275791

申请日：2019-02-14

Applicant: UNIVERSIDADE DO MINHO ,  Nuno Jorge Carvalho Sousa ,  Rui Miguel Da Costa Martins

Inventor： Nuno Jorge Carvalho Sousa ,  Rui Miguel Da Costa Martins ,  Ricardo Alberto Alvarez Osorio

IPC: G01N21/25 ,  A61B5/00 ,  G01N21/31 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495 ,  G01N21/65 ,  G01N33/483

Abstract: Biophotonic device for the point-of-care, real-time, non-invasive determination of parameters with diagnostic relevance, in particular an optical system for parameter characterization of an element of body fluid or tissue comprising an optical device which comprises: a light source for emitting light onto the element; and a spectrometer for recording the spectrum of light from the element, said light from the element being of transmittance, reflectance or Raman scattering of the emitted light by said element; the optical system further comprising a data processing module configured to: convert the recorded spectrum by a conversion matrix into a standardized spectrum, wherein said conversion matrix has been obtained by calibrating the optical system spectrum response against a spectrum reference; pre-process the converted spectrum; correlate, for parameter quantification, the converted pre-processed spectrum with pre-obtained spectral bands for each parameter; said spectrum being contained within uv-vis-nir wavelengths. Also methods of operating said system.

公开(公告)号：US20220202540A1

公开(公告)日：2022-06-30

申请号：US17604101

申请日：2019-05-02

Applicant: UNIVERSIDADE DO MINHO

Inventor： FILIPE SAMUEL CORREIA PEREIRA SILVA ,  PAULO FILIPE SALGADO PINTO ,  ÓSCAR SAMUEL NOVAIS CARVALHO ,  TELMA SOFIA ALVES DANTAS

IPC: A61C8/00

Abstract: A dental implant supported on the cortical bone is implanted in the socket from which the tooth was extracted, if this hole still exists, or in the remaining socket when the tooth was extracted some time before, or alternatively in a hole made for placement of the implant, at cortical bone level, and externally, between the cortical bone and the gingiva, slightly embracing the mandible and the maxilla.
In one embodiment, in order to enhance the fixation and implant lifetime vascularization, the implant of the present disclosure for fitting in an intraosseous zone of a dental socket includes a plurality of raised platforms with a flat top such that said tops form an external surface of the implant for contacting with the intraosseous zone and the spaces between said platforms form a network of channels for revascularisation fluid flow with capillarity properties.

公开(公告)号：US11248591B2

公开(公告)日：2022-02-15

申请号：US16621556

申请日：2018-06-11

Applicant: CENTITVC-CENTRO DE NANOTECNOLOGIA E MATERIAIS TÉCNICOS,FUNCIONAIS E INTELIGENTES ,  UNIVERSIDADE DO MINHO ,  IPCA—INSTITUTO POLITÉCNICO DO CÁVADO E AVE

Inventor： Carlos Diogo Alves Da Costa Gonçalves ,  Ricardo João Ferreira Simões ,  Alexandre Manuel Teixeira De Barros Ferreira Da Silva ,  João Manuel De Carvalho Gomes

IPC: A61F13/08 ,  A61F13/00 ,  F03G7/06 ,  A61H1/00

Abstract: A textile contractible band for use in a wearable garment for applying pressure to a subject body part includes a shape memory material, in particular a shape memory alloy, or shape memory polymer, part and a textile part, said parts being successively coupled to form said contractible band, wherein the shape memory material part has an electrically-contractible shape memory material and a spring arranged to reverse the contraction of the shape memory material, and wherein the textile part has an elastic fabric band and an optical fiber strain sensor arranged to sense the fabric band strain. The sensor can be a lossy optical fiber arranged in meandering layout such that variation of band extension causes variation of transmitted light. The contractual band can be used for lymphedema or venous return.

公开(公告)号：US20210187159A1

公开(公告)日：2021-06-24

申请号：US16755811

申请日：2018-10-15

Applicant: UNIVERSIDADE DO MINHO ,  ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEERING AND CELL BASED TECHNOLOGIES & THERAPIES (A4TEC

Inventor： Ana Rita CRUZ DUARTE ,  Rui L. REIS ,  Jorge Manuel NUNES CORREIA PINTO ,  Rui Miguel FERNANDES DUARTE

IPC: A61L27/18 ,  A61L27/34 ,  A61L27/54 ,  C08L67/04 ,  C08L33/00 ,  C08L77/04 ,  A61M5/20

Abstract: The present disclosure relates to injectable and expandable compositions, devices, kits and methods for use in an approach for the in-situ foaming of polymers for bone or tissue defects, namely to fill and/or fuse a tissue defect. The present disclosure relates to compositions, devices, kits and methods for use in an approach for the in-situ foaming of polymers for bone or tissue defects, namely for bone tissue defect filling/fusion. The design of extendable and expandable compositions for bone fusion is one of the most challenging fields in the intersection of polymer and biomedical engineering. An aspect of the present disclosure relates to an injectable expandable composition for use in medicine, veterinary or cosmetic, comprising a polycaprolactone particle filler; a polydopamine adhesive bound to said filler; a polymethacrylic acid plasticizer bound to said polydopamine adhesive.

公开(公告)号：US11033526B2

公开(公告)日：2021-06-15

申请号：US15559241

申请日：2016-03-17

Applicant: UNIVERSIDADE DO MINHO

Inventor： Patricia Espinheira De Sá Maciel ,  Andreia Cristiana Teixeira De Castro ,  Ana Luísa De Jales Monteiro De Sousa ,  Ana Sofia Teixeira Esteves ,  Nuno Jorge Carvalho Sousa

IPC: A61K31/343 ,  A61P25/28 ,  A61K9/00

Abstract: Citalopram or escitalopram, pharmaceutically acceptable salts or derivatives thereof for use in the treatment of neurodegenerative diseases The disclosure subject matter is related to the use of citalopram or escitalopram, pharmaceutically acceptable salts or derivatives thereof, in the treatment of neurodegenerative diseases that are positively influenced by the decrease of protein misfolding and/or aggregation, in particular by oral administration.