公开(公告)号：US3703546A

公开(公告)日：1972-11-21

申请号：US3703546D

申请日：1968-10-24

Applicant: AMCHEM PROD

Inventor： LEAPER JOSEPH MICHAEL FARADAY ,  RAMAN HARVEY PETER JOHN

IPC: C07C63/70 ,  C07C205/58 ,  C07C101/54

CPC classification number: C07C67/14 ,  C07C201/08 ,  C07C201/16 ,  C07C205/58 ,  C07C69/76

Abstract: 3-AMINO-2,5-DICHLOROBENZOIC ACID IS PREPARED IN HIGH YIELD BY CHLORINATING BENZOYLCHLORIDE AND ESTERIFYING THE RESULTING MIXTURE, SEPARATING THE DESIRED 2,5-DICHLORO ISOMER FROM THE MIXTURE BY FREEZE CRYSTALLIZATION, NITRATING AND ISOLATING 3-NITRO-2,5-DICHLOROBENZOIC ACID FROM THE MIXTURE OF NITRO ISOMERS BY ACID HYDROLYSIS AND TREATING WITH A REDUCING AGENT.