公开(公告)号：US20190012788A1

公开(公告)日：2019-01-10

申请号：US16031485

申请日：2018-07-10

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  AVALUN

Inventor： Jean-Guillaume COUTARD ,  Patrick POUTEAU ,  Myriam Laure CUBIZOLLES

IPC: G06T7/00 ,  G01N33/49 ,  G06T7/60 ,  G01N21/78 ,  G01N21/77

CPC classification number: G06T7/0016 ,  G01N21/78 ,  G01N33/49 ,  G01N2021/7773 ,  G01N2021/7783 ,  G06T7/60

Abstract: The invention is a method for estimating the amount of analyte in a fluid sample, and in particular in a bodily fluid. The sample is mixed with a reagent able to form a color indicator in the presence of the analyte. The sample is then illuminated by a light beam produced by a light source; an image sensor forms an image of the beam transmitted by the sample, from which image a concentration of the analyte in the fluid is estimated. The method is intended to be implemented in compact analyzing systems. One targeted application is the determination of the glucose concentration in blood.

公开(公告)号：US20220317028A1

公开(公告)日：2022-10-06

申请号：US17616908

申请日：2020-06-04

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  CPE LYON FORMATION CONTINUE ET RECHERCHE ,  ECOLE CENTRALE DE LYON ,  INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON ,  UNIVERSITE CLAUDE BERNARD LYON 1 ,  AVALUN ,  COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Inventor： Mathieu DUPOY ,  Taha BENYATTOU ,  Lotfi BERGUIGA ,  Jean-Marc FEDELI ,  Maryse FOURNIER ,  Nicolas GAIGNEBET ,  Cecile JAMOIS ,  Patrick POUTEAU

IPC: G01N21/31

Abstract: A method for analysing a sample uses a resonant support having a surface on which a plurality of separated photonic crystals extends. At least two crystals are configured to capture the same analyte. A resonance wavelength associated with each crystal varies with an amount of analyte in contact with the crystal. The wavelengths define a resonance spectral band between 200-1500 nm. The transmission/reflection of the light is maximum at an associated resonance wavelength. The method includes: illuminating the support in the resonance spectral band, the intensity of the lamination being variable in band; acquiring a measurement image using an image sensor, the image having different regions-of-interest each optically coupled to a photonic crystal; using a reference image representative of an image acquired by the image sensor, when the support is illuminated in the resonance spectral band in a reference configuration; and comparing the measurement image with the reference image.

公开(公告)号：US20180050339A1

公开(公告)日：2018-02-22

申请号：US15554783

申请日：2016-02-26

Applicant: AVALUN

Inventor： Patrick POUTEAU ,  Vincent POHER

IPC: B01L3/00 ,  A61B5/15 ,  A61B5/157 ,  A61B10/00

CPC classification number: B01L3/50273 ,  A61B5/1405 ,  A61B5/150022 ,  A61B5/150061 ,  A61B5/150343 ,  A61B5/150755 ,  A61B5/157 ,  A61B10/0045 ,  A61B10/007 ,  B01L2200/141 ,  B01L2300/042 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/069 ,  B01L2400/0406

Abstract: A device for collecting a liquid sample by capillarity includes distinct first and second elements having respective male and female parts. The male part comprises a channel having a transverse section. The female part comprises a peripheral wall that transversely delimits a cavity to house the male part. A part of the peripheral wall forms a cap to close the transverse section when the female part houses the male part.

公开(公告)号：US20170011517A1

公开(公告)日：2017-01-12

申请号：US15204300

申请日：2016-07-07

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  AVALUN

Inventor： Jean-Guillaume COUTARD ,  Patrick POUTEAU ,  Myriam Laure CUBIZOLLES

IPC: G06T7/00 ,  G06T7/40 ,  G06T7/60

CPC classification number: G06T7/0016 ,  G01N21/78 ,  G01N33/49 ,  G01N2021/7773 ,  G01N2021/7783 ,  G06T7/60

Abstract: The invention is a method for estimating the amount of analyte in a fluid sample, and in particular in a bodily fluid. The sample is mixed with a reagent able to form a color indicator in the presence of the analyte. The sample is then illuminated by a light beam produced by a light source; an image sensor forms an image of the beam transmitted by the sample, from which image a concentration of the analyte in the fluid is estimated. The method is intended to be implemented in compact analyzing systems. One targeted application is the determination of the glucose concentration in blood.

Abstract translation: 本发明是用于估计流体样品中特别是体液中分析物的量的方法。 将样品与分析物存在下能够形成颜色指示剂的试剂混合。 然后由光源产生的光束照射样品; 图像传感器形成由样品透射的光束的图像，从该图像估计流体中分析物的浓度。 该方法旨在在紧凑的分析系统中实现。 一个目标应用是测定血液中的葡萄糖浓度。