公开(公告)号：US11578358B2

公开(公告)日：2023-02-14

申请号：US16312489

申请日：2017-09-14

Applicant: Abbott Laboratories

Inventor： Mark A. Hayden ,  Jeffrey B. Huff ,  Sophie Laurenson ,  Andrew Fischer ,  John Robinson ,  Shelley R. Holets-McCormack

IPC: C12Q1/6853

Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. The detection modules disclosed here can be used for detecting analytes of interest which analytes may have been enriched by amplification, isolation, or other techniques.

公开(公告)号：US20190153524A1

公开(公告)日：2019-05-23

申请号：US16312489

申请日：2017-09-14

Applicant: Abbott Laboratories

Inventor： Mark A. Hayden ,  Jeffrey B. Huff ,  Sophie Laurenson ,  Andrew Fischer ,  John Robinson ,  Shelley R. Holets-McCormack

IPC: C12Q1/6853

Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. The detection modules disclosed here can be used for detecting analytes of interest which analytes may have been enriched by amplification, isolation, or other techniques.