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公开(公告)号：US20080115136A1
公开(公告)日：2008-05-15
申请号：US11969075
申请日：2008-01-03
Applicant: Alan Smith , James Wright
Inventor： Alan Smith , James Wright
IPC: G06F9/46
CPC classification number: G06F11/1438 , G06F2201/80
Abstract: A transfer of control to a batch application is intercepted, wherein a batch front-end routine receives control in place of the batch application and performs initialization processing. This initialization processing comprises issuing a DLI restart call and issuing a DLI checkpoint call. If the DLI restart call returns a checkpoint ID, then one or more databases associated with the batch application are repositioned. The transfer of control to the batch application is then resumed, whereby the batch application restarts from the checkpoint ID, if the checkpoint ID was returned by the DLI restart call, in a manner transparent to the batch application.
Abstract translation: 拦截对批处理应用程序的控制转移，其中批量前端程序代替批处理应用程序接收控制并执行初始化处理。 该初始化处理包括发出DLI重启呼叫并发出DLI检查点呼叫。 如果DLI重新启动调用返回检查点ID，则重新定位与批处理应用程序关联的一个或多个数据库。 然后恢复对批处理应用程序的转移，如果检查点ID由DLI重新启动调用返回，批处理应用程序将以批处理应用程序透明的方式从检查点ID重新启动。
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公开(公告)号：US20080104597A1
公开(公告)日：2008-05-01
申请号：US11969127
申请日：2008-01-03
Applicant: Alan Smith , James Wright
Inventor： Alan Smith , James Wright
IPC: G06F9/46
CPC classification number: G06F11/1438 , G06F2201/80
Abstract: A transfer of control to a batch application is intercepted, wherein a batch front-end routine receives control in place of the batch application and performs initialization processing. This initialization processing comprises issuing a DLI restart call and issuing a DLI checkpoint call. If the DLI restart call returns a checkpoint ID, then one or more databases associated with the batch application are repositioned. The transfer of control to the batch application is then resumed, whereby the batch application restarts from the checkpoint ID, if the checkpoint ID was returned by the DLI restart call, in a manner transparent to the batch application.
Abstract translation: 拦截对批处理应用程序的控制转移，其中批量前端程序代替批处理应用程序接收控制并执行初始化处理。 该初始化处理包括发出DLI重启呼叫并发出DLI检查点呼叫。 如果DLI重新启动调用返回检查点ID，则重新定位与批处理应用程序关联的一个或多个数据库。 然后恢复对批处理应用程序的转移，如果检查点ID由DLI重新启动调用返回，批处理应用程序将以批处理应用程序透明的方式从检查点ID重新启动。
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公开(公告)号：US09308179B2
公开(公告)日：2016-04-12
申请号：US13556647
申请日：2012-07-24
Applicant: Stephen E. Zale , Greg Troiano , Mir M. Ali , Jeff Hrkach , James Wright
Inventor： Stephen E. Zale , Greg Troiano , Mir M. Ali , Jeff Hrkach , James Wright
CPC classification number: A61K9/5153 , A61K9/0019 , A61K9/1641 , A61K31/337 , A61K31/436 , A61K31/475 , A61K31/519 , A61K47/542 , A61K47/593 , A61K47/60 , A61K47/6925 , A61K47/6937 , B82Y5/00
Abstract: The present disclosure is directed in part to a biocompatible nanoparticle composition comprising a plurality of non-colloidal long circulating nanoparticles, each comprising a α-hydroxy polyester-co-polyether and a therapeutic agent, wherein such disclosed compositions provide a therapeutic effect for at least 12 hours.
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4.发明授权Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers 有权具有高玻璃化转变温度或高分子量共聚物的治疗性聚合物纳米颗粒组合物公开(公告)号：US08518963B2
公开(公告)日：2013-08-27
申请号：US13372036
申请日：2012-02-13
Applicant: Mir Mukkaram Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Christina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh Christopher Campbell
Inventor： Mir Mukkaram Ali , Abhimanyu Sabnis , David Dewitt , Greg Troiano , James Wright , Maria Figueiredo , Michael Figa , Christina Van Geen Hoven , Young-Ho Song , Jason Auer , Tarikh Christopher Campbell
CPC classification number: G01N25/4866 , A61K9/0019 , A61K9/146 , A61K9/5153 , A61K31/00 , A61K31/337 , A61K31/427 , A61K31/436 , A61K31/475 , A61K31/573 , A61K31/58 , A61K31/585 , A61K31/69 , A61K47/34
Abstract: The present disclosure relates in part to pharmaceutical compositions comprising polymeric nanoparticles having certain glass transition temperatures. Other aspects of the invention include methods of making such nanoparticles.
Abstract translation: 本公开部分涉及包含具有某些玻璃化转变温度的聚合物纳米颗粒的药物组合物。 本发明的其它方面包括制备这种纳米颗粒的方法。
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公开(公告)号：US20130023898A9
公开(公告)日：2013-01-24
申请号：US12173963
申请日：2008-07-16
Applicant: Yulun Wang , Modjtaba Ghodoussi , Darrin Uecker , James Wright , Amante Mangaser , Ranjan Mukherjee
Inventor： Yulun Wang , Modjtaba Ghodoussi , Darrin Uecker , James Wright , Amante Mangaser , Ranjan Mukherjee
IPC: A61B19/00
CPC classification number: G09B23/28 , A61B34/30 , A61B34/35 , A61B34/37 , A61B34/70 , A61B34/76 , A61B34/77 , A61B90/06 , A61B90/361 , A61B2017/00707 , A61B2034/305 , A61B2090/064 , G05B15/02 , G06F19/00 , G06F19/3418
Abstract: A medical system that allows a mentor to teach a pupil how to use a robotically controlled medical instrument. The system may include a first handle that can be controlled by a mentor to move the medical instrument. The system may further have a second handle that can be moved by a pupil to control the same instrument. Deviations between movement of the handles by the mentor and the pupil can be provided as force feedback to the pupil and mentor handles. The force feedback pushes the pupil's hand to correspond with the mentor's handle movement. The force feedback will also push the mentor's hand to provide information to the mentor on pupil's movements. The mentor is thus able to guide the pupil's hands through force feedback of the pupil handles to teach the pupil how to use the system.
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Patent Agency Ranking
6.发明授权Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same 有权包括长春花生物碱的治疗性聚合物纳米颗粒及其制备和使用方法公开(公告)号：US08318211B2
公开(公告)日：2012-11-27
申请号：US12485467
申请日：2009-06-16
Applicant: Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
Inventor： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
CPC classification number: A61K9/1647 , A61K9/14 , A61K9/1694 , A61K9/19 , A61K9/5153 , A61K31/4745 , A61K31/475 , A61K31/55 , A61K47/26
Abstract: The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer.
Abstract translation: 本公开一般涉及治疗性纳米颗粒。 本文公开的示例性纳米颗粒可包括约1至约20重量％的长春花生物碱; 和约50至约99重量％的生物相容性聚合物。
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7.发明申请公开(公告)号：US20120288541A1
公开(公告)日：2012-11-15
申请号：US13553210
申请日：2012-07-19
Applicant: Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
Inventor： Stephen E. Zale , Greg Troiano , Mir Mukkaram Ali , Jeff Hrkach , James Wright
IPC: A61K9/14 , A61P35/00 , A61K31/337 , B82Y5/00
CPC classification number: A61K47/34 , A61J3/00 , A61K9/10 , A61K9/107 , A61K9/1647 , A61K9/19 , A61K9/5146 , A61K9/5153 , A61K31/337 , A61K31/4355 , A61K31/436 , A61K31/437 , A61K31/439 , A61K31/475 , A61K31/704 , A61K31/7068 , A61K47/6915 , A61K47/6925 , A61K47/6937 , B82Y5/00 , C07C59/08 , Y10S977/773
Abstract: The present disclosure generally relates to nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of biocompatible polymer such as a diblock poly(lactic) acid-poly(ethylene)glycol. Other aspects of the invention include methods of making such nanoparticles.
Abstract translation: 本公开内容通常涉及具有约0.2至约35重量％的治疗剂的纳米颗粒; 和约10至约99重量％的生物相容性聚合物，例如二嵌段聚（乳酸） - 聚（乙烯）二醇。 本发明的其它方面包括制备这种纳米颗粒的方法。
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8.发明授权Method for operating a medical robotic system by stopping movement of a surgical instrument about a pivot point or issuing a warning if the pivot point moves beyond a threshold value 有权用于通过停止手术器械关于枢转点的运动来操作医疗机器人系统的方法或者如果枢转点移动超过阈值则发出警告公开(公告)号：US07785320B2
公开(公告)日：2010-08-31
申请号：US12051957
申请日：2008-03-20
Applicant: Yulun Wang , Darrin R Uecker , Jeff Wilson , Keith Philip Laby , Steve Jordan , James Wright
Inventor： Yulun Wang , Darrin R Uecker , Jeff Wilson , Keith Philip Laby , Steve Jordan , James Wright
IPC: A61B17/00
CPC classification number: A61B17/11 , A61B17/0469 , A61B17/29 , A61B34/30 , A61B34/35 , A61B34/37 , A61B34/70 , A61B34/71 , A61B34/72 , A61B34/75 , A61B34/76 , A61B34/77 , A61B46/10 , A61B50/00 , A61B90/361 , A61B2017/00199 , A61B2017/00243 , A61B2017/00252 , A61B2017/0046 , A61B2017/00477 , A61B2017/00703 , A61B2017/00973 , A61B2017/1107 , A61B2017/1135 , A61B2017/2927 , A61B2017/2929 , A61B2034/2059 , A61B2034/742 , A61B2090/064 , B25J9/1689 , G05B2219/45119
Abstract: A system for performing minimally invasive cardiac procedures. The system includes a pair of surgical instruments that are coupled to a pair of robotic arms. The instruments have end effectors that can be manipulated to hold and suture tissue. The robotic arms are coupled to pair of master handles by a controller. The handles can be moved by the surgeon to produce a corresponding movement of the end effectors. The controller controls and limits movement of robotic arms relative to the patient.
Abstract translation: 用于执行微创心脏手术的系统。 该系统包括耦合到一对机器人臂的一对外科器械。 仪器具有能够被操纵以保持和缝合组织的末端效应器。 机器臂通过控制器耦合到一对主手柄。 手柄可由外科医生移动以产生末端执行器的相应运动。 控制器控制和限制机器人臂相对于患者的运动。
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9.发明申请公开(公告)号：US20100216804A1
公开(公告)日：2010-08-26
申请号：US12638297
申请日：2009-12-15
Applicant: Stephen E. Zale , Greg Troiano , Mir M. Ali , Jeff Hrkach , James Wright , Susan Low
Inventor： Stephen E. Zale , Greg Troiano , Mir M. Ali , Jeff Hrkach , James Wright , Susan Low
IPC: A61K9/14 , A61K31/337 , A61K31/4745 , A61K31/519 , A61K31/436 , A61P35/00
CPC classification number: A61K9/5153 , A61K9/0019 , A61K9/1641 , A61K31/337 , A61K31/436 , A61K31/475 , A61K31/519 , A61K47/542 , A61K47/593 , A61K47/60 , A61K47/6925 , A61K47/6937 , B82Y5/00
Abstract: The present disclosure is directed in part to a biocompatible nanoparticle composition comprising a plurality of non-colloidal long circulating nanoparticles, each comprising a α-hydroxy polyester-co-polyether and a therapeutic agent, wherein such disclosed compositions provide a therapeutic effect for at least 12 hours.
Abstract translation: 本公开部分地涉及生物相容性纳米颗粒组合物，其包含多个非胶体长循环纳米颗粒，每个非胶体长循环纳米颗粒包含α-羟基聚酯 - 共聚醚和治疗剂，其中所述公开的组合物至少提供治疗效果 12小时。
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公开(公告)号：US20090012544A1
公开(公告)日：2009-01-08
申请号：US12135989
申请日：2008-06-09
Applicant: Chris Thompson , Mitchell Roslin , Mitchell Dann , Greg Fluet , James Wright
Inventor： Chris Thompson , Mitchell Roslin , Mitchell Dann , Greg Fluet , James Wright
IPC: A61B17/11
CPC classification number: A61B17/1114 , A61B17/11 , A61B2017/00557 , A61B2017/0647 , A61F2002/045
Abstract: Disclosed herein are systems and methods for treating a patient that has undergone a bariatric surgical procedure, to promote weight loss in the patient. The systems and methods can involve positioning a gastrointestinal bypass sleeve within a portion of the altered GI anatomy to create or restore a restriction, and/or create a malabsorptive effect via a gastric and partial intestinal bypass. The bypass sleeve can include a proximal attachment element for attaching the proximal end of the sleeve in a penetrating or non-penetrating manner at the gastroesophageal junction, stomach, neo-stomach, or other locations. The bypass can be placed during the same operative session as the bariatric surgical procedure, or alternatively at a later date.
Abstract translation: 本文公开了用于治疗已经进行减肥手术的患者的系统和方法，以促进患者的体重减轻。 系统和方法可以包括将胃肠旁路套管定位在改变的GI解剖结构的一部分内以产生或恢复限制，和/或通过胃和部分肠旁路产生吸收不良的作用。 旁路套管可以包括用于以穿透或非穿透方式在胃食管接合部，胃，新胃或其他位置附接套筒的近端的近端附接元件。 旁路可以在与减肥手术相同的手术期间放置，或者在稍后的日期。
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