公开(公告)号：US20230398021A1

公开(公告)日：2023-12-14

申请号：US18334256

申请日：2023-06-13

Applicant: Alcon Inc.

Inventor： Andrew T. SCHIEBER ,  Iqbal K. AHMED

IPC: A61F9/00 ,  A61F9/007

CPC classification number: A61F9/0017 ,  A61F9/00781

Abstract: An ocular implant adapted to be disposed within Schlemm's canal of a human eye with a body extending along a curved longitudinal central axis in a curvature plane, a first strut on one side of the implant and a second strut on an opposite side of the implant, the circumferential extent of the first strut with respect to the plane of curvature being greater than the circumferential extent of the second strut with respect to the plane of curvature. The invention also includes methods of using the implant.

公开(公告)号：US20240307225A1

公开(公告)日：2024-09-19

申请号：US18585332

申请日：2024-02-23

Applicant: Alcon Inc.

Inventor： Andrew T. SCHIEBER ,  Charles L. EUTENEUER ,  David T. VAN METER ,  Kenneth M. GALT

IPC: A61F9/007 ,  A61B3/16 ,  A61M5/00 ,  A61M25/00

CPC classification number: A61F9/00781 ,  A61B3/16 ,  A61M5/00 ,  A61M25/00

Abstract: An illustrative method for reducing intraocular pressure in a patient may comprise deploying an ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye and administering a therapeutic agent comprising a Rho kinase (ROCK) inhibitor to the patient. The ocular implant may be configured to lower the intraocular pressure from an initial to a second pressure within a first range and the therapeutic agent may lower an intraocular pressure to a third pressure within a second range, the third pressure lower than the second pressure.

公开(公告)号：US20240390184A1

公开(公告)日：2024-11-28

申请号：US18792833

申请日：2024-08-02

Applicant: Alcon Inc.

Inventor： John WARDLE ,  Andrew T. SCHIEBER

IPC: A61F9/00 ,  A61B17/34 ,  A61F9/007

Abstract: A method of deploying an ocular implant into Schlemm's canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm's canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.

公开(公告)号：US20240293260A1

公开(公告)日：2024-09-05

申请号：US18658669

申请日：2024-05-08

Applicant: Alcon Inc.

Inventor： Andrew T. SCHIEBER ,  Charles L. EUTENEUER

IPC: A61F9/007

CPC classification number: A61F9/00781

Abstract: A method of inserting an ocular implant into Schlemm's canal, the method comprising: moving the ocular implant into Schlemm's canal; and injecting a visco-elastic medium in front of the implant.

公开(公告)号：US20240216172A1

公开(公告)日：2024-07-04

申请号：US18426851

申请日：2024-01-30

Applicant: Alcon Inc.

Inventor： John WARDLE ,  Andrew T. SCHIEBER

IPC: A61F9/007 ,  A61F9/00

CPC classification number: A61F9/00781 ,  A61F9/0017

Abstract: An ocular implant delivery system is provided with a number of features. In some embodiments, the delivery system comprises a rotation mechanism configured to rotate and orient a cannula of the system, and an advancement mechanism configured to advance and retract an ocular implant through the delivery system and into an eye of a patient. In some embodiments, the cannula is sized and configured to be inserted into Schlemm's canal of the eye. The ocular implant is configured to maintain its orientation within the delivery system as the cannula is rotated. In some embodiments, the ocular implant automatically disengages the delivery system when it is advanced beyond a distal tip of the delivery system. Methods of implanting an ocular implant are also provided.