System and method for determining a force applied to or generated by a cell or tissue culture

    公开(公告)号:US11685887B2

    公开(公告)日:2023-06-27

    申请号:US15781454

    申请日:2016-12-02

    CPC classification number: C12M35/04 C12M35/06 G01L1/127

    Abstract: Technologies and implementations for a system and method for determining a force applied to a cell or tissue culture is disclosed. The system and method may include an elastic element mounted in or suitable for mounting in a culture chamber. The elastic element may be adapted to be coupled with the cell or the tissue culture such that a force applied to the cell or the tissue culture leads to a deflection of the elastic element against a restoring force. A magnetic field sensor may be mounted outside said culture chamber. The magnetic field sensor may be adapted to detect a change of magnetic field attributable to a corresponding movement of a magnetic element upon deflection.

    SYSTEM AND METHOD FOR DETERMINING A FORCE APPLIED TO OR GENERATED BY A CELL OR TISSUE CULTURE

    公开(公告)号:US20240150700A1

    公开(公告)日:2024-05-09

    申请号:US18213126

    申请日:2023-06-22

    CPC classification number: C12M35/04 C12M35/06 G01L1/127

    Abstract: The invention relates to a system (10) for determining a force applied to a cell or tissue culture (14) arranged in a culture chamber (12), comprising an elastic element (30) mounted in or suitable for mounting in said culture chamber (12), said elastic element (30) being adapted to be coupled with said cell or tissue culture (14) such that a force applied to said cell or tissue culture (14) leads to a deflection of said elastic element (30) against a restoring force thereof, and said elastic element comprising a magnetic element (34) arranged such as to be moved upon deflection of said elastic element (30), a magnetic field sensor (42) mounted or suitable for mounting outside said culture chamber (12), said magnetic field sensor (42), when mounted outside said culture chamber (12), being adapted to detect a change of magnetic field attributable to a corresponding movement of said magnetic element (34) upon deflection of said elastic element (30).

    A SYSTEM AND METHOD FOR DETERMINING A FORCE APPLIED TO OR GENERATED BY A CELL OR TISSUE CULTURE

    公开(公告)号:US20200255789A1

    公开(公告)日:2020-08-13

    申请号:US15781454

    申请日:2016-12-02

    Abstract: The invention relates to a system (10) for determining a force applied to a cell or tissue culture (14) arranged in a culture chamber (12), comprising an elastic element (30) mounted in or suitable for mounting in said culture chamber (12), said elastic element (30) being adapted to be coupled with said cell or tissue culture (14) such that a force applied to said cell or tissue culture (14) leads to a deflection of said elastic element (30) against a restoring force thereof, and said elastic element comprising a magnetic element (34) arranged such as to be moved upon deflection of said elastic element (30), a magnetic field sensor (42) mounted or suitable for mounting outside said culture chamber (12), said magnetic field sensor (42), when mounted outside said culture chamber (12), being adapted to detect a change of magnetic field attributable to a corresponding movement of said magnetic element (34) upon deflection of said elastic element (30).

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