公开(公告)号：US20230286972A1

公开(公告)日：2023-09-14

申请号：US18019270

申请日：2021-08-03

Applicant: BIOGEN MA INC.

Inventor： Asmerom Weldeab ,  Tae Kim Correia ,  Aireal Diane Jenkins ,  Yiqing Lin ,  Chaomin Li

IPC: C07D417/14

CPC classification number: C07D417/14 ,  C07B2200/13

Abstract: Described herein are solid forms of N-(4-fluoro-5-(((2S,4R)-4-46-methoxypyrimidin-4-yl)oxy)-2-methylpyrrolidin-1-yl)methyl)thiazol-2-yl)acetamide, compound (I): (I) and the process of making said solid forms of compound (I). The present invention further relates to a pharmaceutical composition comprising crystalline Form A and Form B of compound (I), and methods of using said form and pharmaceutical composition in the treatment and prevention of Alzheimer's disease and related neurological disorders.