公开(公告)号：US11572405B2

公开(公告)日：2023-02-07

申请号：US16768838

申请日：2019-01-11

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Michael Carleton ,  David Feltquate ,  Olivier De Henau ,  Timothy Patrick Reilly ,  Tian Chen ,  Ye Feng ,  Shu-Pang Ben Huang ,  Ming Zhou ,  Ramachandran Suresh

IPC: C07K16/24 ,  A61P35/04 ,  A61P35/00 ,  A61K39/395 ,  C07K16/28 ,  G01N33/68 ,  A61K39/00

Abstract: Provided herein are methods for the clinical treatment of tumors (e.g., advanced solid tumors) in patients having certain levels of serum IL-8 using an anti-IL-8 antibody in combination with an anti-PD-1 antibody.