公开(公告)号：US20140356446A1

公开(公告)日：2014-12-04

申请号：US14461845

申请日：2014-08-18

Applicant: Biomet Biologics, LLC

Inventor： Michael D. LEACH ,  Joel C. HIGGINS ,  Matthew SWIFT ,  Nathan GORDON

IPC: A61K35/12 ,  A61M1/36

CPC classification number: A61K35/12 ,  A61M1/3693 ,  B01L3/502 ,  B01L3/5021 ,  B01L3/50215 ,  B01L9/54 ,  B01L2200/026 ,  B01L2300/0681 ,  B01L2400/0409 ,  B01L2400/0478 ,  B01L2400/0605 ,  G01N33/491

Abstract: An apparatus may allow separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.

Abstract translation: 装置可以允许分离和收集样品的一部分。 当与离心机一起使用时，该装置允许在装置中产生至少三个级分。 它还提供了一种从全骨样细胞和骨髓间充质干细胞中提取血沉棕黄层的新方法。 可以使用可包括第一浮标部分和可操作地连接的第二浮标部件的浮标系统，以在基本上单个的离心过程期间从样品形成至少三个级分。 因此，各种馏分的分离可以基本上快速有效。

公开(公告)号：US20140322430A1

公开(公告)日：2014-10-30

申请号：US14330778

申请日：2014-07-14

Applicant: Biomet Biologics, LLC

Inventor： Matthew SWIFT

IPC: A61F13/00

CPC classification number: A61F13/00991 ,  A61F2/0063 ,  B05B7/08 ,  B05B12/16

Abstract: A device for spraying a biological substance onto a biocompatible implant. The device includes a housing that defines a sterile chamber. A spray head is within the chamber and proximate to a first end. A first conduit is configured to direct the biological substance into the chamber through a first spray tip of the spray head. A second conduit is configured to direct an activator into the chamber through a second spray tip of the spray head. A third conduit is configured to direct compressed air to the chamber through a third spray tip of the spay head. The spray head is configured to direct a coating of the biological substance as activated by the activator to the implant seated within the chamber at a second end that is opposite to the first end.

Abstract translation: 用于将生物物质喷洒到生物相容性植入物上的装置。 该装置包括限定无菌室的壳体。 喷雾头在腔室内并靠近第一端。 第一导管构造成通过喷头的第一喷嘴将生物物质引导到腔室中。 第二导管构造成通过喷头的第二喷嘴将活化剂引导到腔室中。 第三导管构造成通过喷头的第三喷嘴将压缩空气引导到腔室。 喷头被构造成将由激活剂激活的生物物质的涂层引导到位于腔室内的植入物处于与第一端相对的第二端。

公开(公告)号：US20140034567A1

公开(公告)日：2014-02-06

申请号：US14047363

申请日：2013-10-07

Applicant: Biomet Biologics, LLC

Inventor： Matthew SWIFT ,  Barry F. HECKER ,  Michael D. LEACH

IPC: A61M1/36

CPC classification number: A61M1/3679 ,  A61M2202/0427 ,  B01D15/00 ,  B01D17/0202 ,  B01D17/0217 ,  B01D17/10 ,  B01J20/046 ,  B01J20/10 ,  B01J20/26 ,  B01J20/261 ,  B01J20/262 ,  B01J2220/46

Abstract: A method and apparatus for obtaining various components of a multi-component material. Generally, a component of a whole blood sample may be concentrated from a patient and re-introduced to the same patient. For example, a clotting component, such as thrombin, from a whole blood sample may be extracted and concentrated in an apparatus and collection to be reapplied or reintroduced into a patient.

Abstract translation: 一种用于获得多组分材料的各种组分的方法和设备。 通常，全血样品的组分可以从患者集中并重新引入同一患者。 例如，来自全血样品的凝血组分（例如凝血酶）可以被提取并浓缩在装置和集合中以被重新施用或重新引入患者体内。