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    Quinolone derivatives and processes for the preparation thereof
    1.
    发明授权
    Quinolone derivatives and processes for the preparation thereof 失效
    喹诺酮衍生物及其制备方法

    公开(公告)号：US5677456A

    公开(公告)日：1997-10-14

    申请号：US438886

    申请日：1995-05-10

    Applicant: Wan Joo Kim ,  Tae Ho Park ,  Moon Hwan Kim ,  Jewn Giew Park ,  Bong Jin Kim

    Inventor： Wan Joo Kim ,  Tae Ho Park ,  Moon Hwan Kim ,  Jewn Giew Park ,  Bong Jin Kim

    IPC: A61K31/435 ,  A61P31/04 ,  C07D471/04 ,  C07D519/00

    CPC classification number: C07D471/04 ,  Y02P20/55

    Abstract: The present invention relates to optical isomers of quinoline compounds of Formula (IA) or Formula (IA'), their pharmaceutically acceptable salts and their intermediates: ##STR1## In the above formulae, A represent nitrogen or ##STR2## in which Y represents hydrogen, halogen such as fluorine or chlorine, lower alkyl or lower alkoxy such as methoxy, or together with R.sub.1 forms --CH.sub.2 CH.sub.2 CH.sub.2 --, --CH.sub.2 CH.sub.2 CH(CH.sub.3)--, --OCH.sub.2 CH.sub.2 --, --OCH.sub.2 CH(CH.sub.3)--, --SCH.sub.2 CH.sub.2 -- or --SCH.sub.2 CH(CH.sub.3)--; R.sub.1 is as defined above or represents straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms, a straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms which is substituted with a halogen atom, a phenyl group or a phenyl group substituted with one or two halogen atoms, such as ethyl, cyclopropyl or 2,4-difluorophenyl; R.sup.4 represents hydrogen, lower alkyl, lower alkoxy, or an amino-protecting group, such as methyl, ethyl or butoxycarbonyl; R.sub.5, R.sub.6, R.sub.7 and R.sub.8 may be the same or different and represent independently hydrogen, lower alkyl optionally substituted by amino, hydroxy or halogen, such as methyl or ethyl; and X represents hydrogen, halogen such as fluorine or chlorine, amino or lower alkyl such as methyl.

    Abstract translation: 本发明涉及式（IA）或式（IA'）喹啉化合物及其药学上可接受的盐及其中间体的光学异构体：其中A表示 氮或其中Y表示氢的卤素，例如氟或氯的卤素，低级烷基或低级烷氧基如甲氧基，或与R 1一起形成-CH 2 CH 2 CH 2 - ， - CH 2 CH 2 CH（CH 3） - ， - OCH 2 CH 2 - ， - OCH 2 CH（ CH 3） - ， - SCH 2 CH 2 - 或-SCH 2 CH（CH 3） - ; R1如上所定义，或表示具有1至3个碳原子的直链或环状低级烷基，被卤素原子，苯基或苯基取代的具有1至3个碳原子的直链或环状低级烷基 被一个或两个卤素原子取代，例如乙基，环丙基或2,4-二氟苯基; R4表示氢，低级烷基，低级烷氧基或氨基保护基，例如甲基，乙基或丁氧基羰基; R5，R6，R7和R8可以相同或不同，独立地表示氢，任意被氨基，羟基或卤素取代的低级烷基如甲基或乙基; X表示氢，卤素如氟或氯，氨基或低级烷基如甲基。

    Quinolone derivatives and processes for the preparation thereof
    4.
    发明授权
    Quinolone derivatives and processes for the preparation thereof 失效
    新型喹诺酮衍生物及其制备方法

    公开(公告)号：US5817820A

    公开(公告)日：1998-10-06

    申请号：US277601

    申请日：1994-07-20

    Applicant: Wan Joo Kim ,  Tae Ho Park ,  Moon Hwan Kim ,  Jewn Giew Park ,  Bong Jin Kim

    Inventor： Wan Joo Kim ,  Tae Ho Park ,  Moon Hwan Kim ,  Jewn Giew Park ,  Bong Jin Kim

    IPC: A61K31/435 ,  A61P31/04 ,  C07D471/04 ,  C07D519/00 ,  C07D215/56

    CPC classification number: C07D471/04 ,  Y02P20/55

    Abstract: The present invention relates to optical isomers of quinoline compounds of Formula (IA) or Formula (IA'), their pharmaceutically acceptable salts and their intermediates: ##STR1## In the above formulae, A represent nitrogen or ##STR2## in which Y represents hydrogen, halogen such as fluorine or chlorine, lower alkyl or lower alkoxy such as methoxy, or together with R.sub.1 forms --CH.sub.2 CH.sub.2 CH.sub.2 --, CH.sub.2 CH.sub.2 CH(CH.sub.3)--, --OCH.sub.2 CH.sub.2 --, --OCH.sub.2 CH(CH.sub.3)--, --SCH.sub.2 CH.sub.2 -- or --SCH.sub.2 CH(CH.sub.3)--; R.sub.1 is as defined above or represents straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms, a straight chain or cyclic lower alkyl group having 1 to 3 carbon atoms which is substituted with a halogen atom, a phenyl group or a phenyl group substituted with one or two halogen atoms, such as ethyl, cyclopropyl or 2,4-difluorophenyl; R.sub.4 represents hydrogen, lower alkyl, lower alkoxy, or an amino-protecting group, such as methyl, ethyl or butoxycarbonyl; R.sub.5, R.sub.6, R.sub.7 and R.sub.8 may be the same or different and represent independently hydrogen, lower alkyl optionally substituted by amino, hydroxy or halogen, such as methyl or ethyl; and X represents hydrogen, halogen such as fluorine or chlorine, amino or lower alkyl such as methyl.

    Abstract translation: 本发明涉及式（IA）或式（IA'）喹啉化合物及其药学上可接受的盐及其中间体的光学异构体：其中A表示 氮或其中Y代表氢，卤素如氟或氯，低级烷基或低级烷氧基如甲氧基，或与R 1一起形成-CH 2 CH 2 CH 2 - ，CH 2 CH 2 CH（CH 3） - ， - OCH 2 CH 2 - ， - OCH 2 CH（CH 3） ） - ， - SCH 2 CH 2 - 或-SCH 2 CH（CH 3） - ; R1如上所定义，或表示具有1至3个碳原子的直链或环状低级烷基，被卤原子，苯基或苯基取代的具有1至3个碳原子的直链或环状低级烷基 被一个或两个卤素原子取代，例如乙基，环丙基或2,4-二氟苯基; R4表示氢，低级烷基，低级烷氧基或氨基保护基，例如甲基，乙基或丁氧基羰基; R5，R6，R7和R8可以相同或不同，独立地表示氢，任意被氨基，羟基或卤素取代的低级烷基如甲基或乙基; X表示氢，卤素如氟或氯，氨基或低级烷基如甲基。

    Artificial turf system having shock absorbing pad
    5.
    发明授权
    Artificial turf system having shock absorbing pad 有权

    公开(公告)号：US12195930B1

    公开(公告)日：2025-01-14

    申请号：US18235926

    申请日：2023-08-21

    Applicant: Bong Jin Kim

    Inventor： Bong Jin Kim ,  Soo Hyoung Kim

    IPC: E01C13/08

    Abstract: An artificial turf system includes: a lower member located to come into close contact with the ground; an upper member spaced apart from the lower member; the shock absorbing pad placed between the lower member and the upper member and made of materials having given elasticity to absorb the shock received from the artificial turf assembly; and the artificial turf assembly seated onto the top of the upper member and having a backing cloth having brushes located on one surface thereof, silica sand poured inside the brushes where artificial turf is planted, and the artificial turf fixed to the inside of the brushes and made of an antibacterial material.

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