公开(公告)号：US11104663B2

公开(公告)日：2021-08-31

申请号：US16650670

申请日：2018-09-28

Applicant: CRITITECH, INC.

Inventor： Mark Williams ,  Jacob Sittenauer ,  Shelby Clark ,  Joseph Farthing ,  Michael Baltezor ,  Matthew McClorey

IPC: C07D401/10 ,  A61K9/14 ,  A61K9/00 ,  A61P31/04

Abstract: The present disclosure relates to ciprofloxacin polymorphs and their use in treating infections.

公开(公告)号：US11738029B2

公开(公告)日：2023-08-29

申请号：US18053557

申请日：2022-11-08

Applicant: CRITITECH, INC.

Inventor： Jacob Sittenauer ,  Aranza Barreda Abarca ,  Shelby Clark ,  Joseph Farthing ,  Mark Williams ,  Gere Dizerega ,  Michael Baltezor

IPC: A61K31/55 ,  A61K9/16

CPC classification number: A61K31/55 ,  A61K9/16 ,  A61K9/1688

Abstract: Compositions of particles having at least 95% by weight of rucaparib and a specific surface area (SSA) of at least 12 m2/g, methods for their use, and methods for their production are provided.

公开(公告)号：US11738014B2

公开(公告)日：2023-08-29

申请号：US18053491

申请日：2022-11-08

Applicant: CRITITECH, INC.

Inventor： Jacob Sittenauer ,  Aranza Barreda Abarca ,  Shelby Clark ,  Joseph Farthing ,  Mark Williams ,  Gere Dizerega ,  Michael Baltezor

IPC: A61K31/454 ,  A61K9/16 ,  A61K9/00

CPC classification number: A61K31/454 ,  A61K9/008 ,  A61K9/1688

Abstract: Compositions of particles having at least 95% by weight of niraparib and a specific surface area (SSA) of at least 5 m2/g, methods for their use, and methods for their production are provided.

公开(公告)号：US12029818B2

公开(公告)日：2024-07-09

申请号：US17812479

申请日：2022-07-14

Applicant: CRITITECH, INC.

Inventor： Jacob Sittenauer ,  Joseph Farthing ,  Mark Williams ,  Michael Baltezor ,  Gere Dizerega ,  Aranza Barreda Abarca ,  Shelby Clark

IPC: A61K9/14 ,  A61K31/5365 ,  A61K47/26

CPC classification number: A61K9/14 ,  A61K31/5365 ,  A61K47/26

Abstract: The disclosure provides particles of at least 95% by weight of lapatinib, or a pharmaceutically acceptable salt thereof, wherein the particles have a specific surface area (SSA) of at least 10 m2/g and have a mean particle size by volume distribution of between about 0.7 μm and about 8 μm.

公开(公告)号：US20240156861A1

公开(公告)日：2024-05-16

申请号：US18492232

申请日：2023-10-23

Applicant: CRITITECH, INC.

Inventor： Michael Baltezor ,  Holly Maulhardt ,  Maria Montes-Gonzalez ,  Jahna Espinosa ,  Mark Williams ,  Joseph Farthing ,  Jacob Sittenauer

IPC: A61K33/243 ,  A61K9/10 ,  A61K47/10 ,  A61P35/00

CPC classification number: A61K33/243 ,  A61K9/10 ,  A61K47/10 ,  A61P35/00

Abstract: Suspensions and their use for treating tumors are provided, where the suspensions include (a) particles of at least 95% by weight of cisplatin, wherein the particles have a specific surface area (SSA) of at least 3.5 m2/g, (b) about 40% to about 60% w/w of glycerin, (c) about 20% to about 40% w/w of propylene glycol, (d) about 5% to about 20% w/w of ethanol, and (e) about 5% to about 10% w/w of 0.9% sodium chloride in water.

公开(公告)号：US11931368B2

公开(公告)日：2024-03-19

申请号：US16650961

申请日：2018-09-28

Applicant: CRITITECH, INC.

Inventor： Michael Baltezor ,  Matthew McClorey ,  Joseph S. Farthing ,  Mark Williams ,  Jacob Sittenauer

IPC: A61K31/569 ,  A61K9/00 ,  A61K9/16 ,  A61K31/496 ,  A61P9/00

CPC classification number: A61K31/569 ,  A61K9/0075 ,  A61K9/1688 ,  A61K31/496 ,  A61P9/00

Abstract: Disclosed herein are particles of at least 95% by weight of a glucocorticoid that have a specific surface area of at least 10 m2/g, methods for making, such particles, and methods for their use as therapeutics. Also disclosed herein are particles of at least 95% by weight of an indolinone that have a specific surface area of at least 10 m2/g, methods for making such particles, and methods for-their use as therapeutics.