公开(公告)号：US20230172927A1

公开(公告)日：2023-06-08

申请号：US17931468

申请日：2022-09-12

Applicant: CRITITECH, INC.

Inventor： Mike Baltezor ,  Gere diZerega ,  Charles Decedue ,  Sam Campbell ,  Matt McClorey

IPC: A61K31/475 ,  A61K9/00 ,  A61K47/26 ,  A61K9/10 ,  A61K9/14 ,  A61K33/243 ,  A61K31/337 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7068 ,  A61P35/00 ,  A61K9/08

CPC classification number: A61K31/475 ,  A61K9/0019 ,  A61K47/26 ,  A61K9/10 ,  A61K9/14 ,  A61K33/243 ,  A61K31/337 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7068 ,  A61P35/00 ,  A61K9/08 ,  A61K47/10

Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.

公开(公告)号：US10894045B2

公开(公告)日：2021-01-19

申请号：US16714151

申请日：2019-12-13

Applicant: CRITITECH, INC.

Inventor： Mike Baltezor ,  Gere diZerega ,  Charles Decedue ,  Sam Campbell ,  Matt McClorey

IPC: A61K31/475 ,  A61K9/00 ,  A61K47/26 ,  A61K9/10 ,  A61K9/14 ,  A61K33/243 ,  A61K31/337 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7068 ,  A61P35/00 ,  A61K9/08 ,  A61K47/10

Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.

公开(公告)号：US11737972B2

公开(公告)日：2023-08-29

申请号：US18046002

申请日：2022-10-12

Applicant: CRITITECH, INC.

Inventor： Gere S. diZerega ,  Michael Baltezor ,  Charles J. Decedue ,  Sam Campbell ,  Matthew McClorey ,  Marc Iacobucci ,  Holly Maulhardt

IPC: A61K9/10 ,  A61K9/00 ,  A61P35/00 ,  A61B8/08 ,  A61B8/12 ,  A61K9/107 ,  A61K9/14 ,  A61K31/337 ,  A61K47/26 ,  A61P1/18 ,  A61K9/16

CPC classification number: A61K9/0019 ,  A61B8/0841 ,  A61B8/12 ,  A61K9/10 ,  A61K9/107 ,  A61K9/14 ,  A61K31/337 ,  A61K47/26 ,  A61P1/18 ,  A61P35/00 ,  A61K9/1688

Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.

公开(公告)号：US20230111288A1

公开(公告)日：2023-04-13

申请号：US18046002

申请日：2022-10-12

Applicant: CRITITECH, INC.

Inventor： Gere S. diZerega ,  Michael Baltezor ,  Charles J. Decedue ,  Sam Campbell ,  Matthew McClorey ,  Marc Iacobucci ,  Holly Maulhardt

IPC: A61K9/00 ,  A61P35/00 ,  A61B8/08 ,  A61B8/12 ,  A61K9/107 ,  A61K9/14 ,  A61K31/337 ,  A61K47/26 ,  A61P1/18 ,  A61K9/10

Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.

公开(公告)号：US20200246326A1

公开(公告)日：2020-08-06

申请号：US16839737

申请日：2020-04-03

Applicant: CRITITECH, INC.

Inventor： Mike Baltezor ,  Gere diZerega ,  Charles Decedue ,  Sam Campbell ,  Matt McClorey

IPC: A61K31/475 ,  A61K9/00 ,  A61P35/00 ,  A61K47/26 ,  A61K33/243 ,  A61K31/7068 ,  A61K31/7048 ,  A61K31/704 ,  A61K31/555 ,  A61K31/513 ,  A61K31/4745 ,  A61K31/4439 ,  A61K31/337 ,  A61K9/14 ,  A61K9/10 ,  A61K9/08

Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small amounts of a polysorbate, and a carrier.

公开(公告)号：US10391090B2

公开(公告)日：2019-08-27

申请号：US16136502

申请日：2018-09-20

Applicant: CRITITECH, INC.

Inventor： Mike Baltezor ,  Gere diZerega ,  Charles Decedue ,  Sam Campbell ,  Matt McClorey

IPC: A61K9/51 ,  A61K9/16 ,  A61K31/337 ,  A61K31/475 ,  A61K9/00 ,  A61K47/26 ,  A61K9/10 ,  A61K9/14 ,  A61P35/00 ,  A61K9/08 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7068 ,  A61K33/243 ,  A61K47/10

Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small, amounts of a polysorbate, and a carrier.

公开(公告)号：US12128131B2

公开(公告)日：2024-10-29

申请号：US18351711

申请日：2023-07-13

Applicant: CRITITECH, INC.

Inventor： Gere S. diZerega ,  Michael Baltezor ,  Charles J. Decedue ,  Sam Campbell ,  Matthew McClorey ,  Marc Iacobucci ,  Holly Maulhardt

IPC: A61K9/10 ,  A61B8/08 ,  A61B8/12 ,  A61K9/00 ,  A61K9/107 ,  A61K9/14 ,  A61K31/337 ,  A61K47/26 ,  A61P1/18 ,  A61P35/00 ,  A61K9/16

CPC classification number: A61K9/0019 ,  A61B8/0841 ,  A61B8/12 ,  A61K9/10 ,  A61K9/107 ,  A61K9/14 ,  A61K31/337 ,  A61K47/26 ,  A61P1/18 ,  A61P35/00 ,  A61K9/1688

Abstract: Disclosed herein are methods for treating epithelial cysts, including pancreatic cysts, in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.

公开(公告)号：US11058639B2

公开(公告)日：2021-07-13

申请号：US16834155

申请日：2020-03-30

Applicant: CRITITECH, INC.

Inventor： Gere S. Dizerega ,  Michael Baltezor ,  Sam Campbell ,  Charles J. Decedue ,  Matthew McClorey

IPC: A61K9/16 ,  A61K31/337 ,  C07K16/28 ,  A61K9/00 ,  A61K39/00

Abstract: Disclosed are combination therapy methods useful for the therapeutic treatment of cancer by combining local administration of compositions containing antineoplastic particles, such as taxane particles, with systemic administration of compositions containing immunotherapeutic agents. Local administration methods include topical application, pulmonary administration, intratumoral injection, intraperitoneal injection, and intracystic injection.

公开(公告)号：US20190254957A1

公开(公告)日：2019-08-22

申请号：US16382446

申请日：2019-04-12

Applicant: CRITITECH, INC.

Inventor： Gere S. diZerega ,  Michael Baltezor ,  Charles J. Decedue ,  Sam Campbell ,  Matthew McClorey ,  Marc Iacobucci ,  Holly Maulhardt

IPC: A61K9/00 ,  A61B8/08 ,  A61B8/12 ,  A61K9/107 ,  A61K47/26 ,  A61K9/14 ,  A61K31/337 ,  A61P35/00

Abstract: Disclosed herein are methods for treating epithelial cysts including pancreatic cysts in a subject by intracystic injection of compositions comprising antineoplastic particles, including taxane particles such as paclitaxel particles and docetaxel particles.

公开(公告)号：US20190022081A1

公开(公告)日：2019-01-24

申请号：US16136502

申请日：2018-09-20

Applicant: CRITITECH, INC.

Inventor： Mike Baltezor ,  Gere diZerega ,  Charles Decedue ,  Sam Campbell ,  Matt McClorey

IPC: A61K31/475 ,  A61P35/00 ,  A61K47/10 ,  A61K47/26 ,  A61K9/10 ,  A61K9/00 ,  A61K9/14 ,  A61K9/08

CPC classification number: A61K31/475 ,  A61K9/0019 ,  A61K9/08 ,  A61K9/10 ,  A61K9/14 ,  A61K31/337 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/513 ,  A61K31/555 ,  A61K31/704 ,  A61K31/7048 ,  A61K31/7068 ,  A61K33/243 ,  A61K47/10 ,  A61K47/26 ,  A61P35/00

Abstract: Disclosed herein are methods for treating solid tumors by direct injection into the tumors of chemotherapeutic particles, methods for inhibiting tumor metastasis by administering chemotherapeutic particles to a subject having a tumor, and compositions that include chemotherapeutic particles, small, amounts of a polysorbate, and a carrier.