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    Dialkyl sulfosuccinate compositions, method of making, and method of use
    1.
    发明授权
    Dialkyl sulfosuccinate compositions, method of making, and method of use 有权

    公开(公告)号：US10022328B2

    公开(公告)日：2018-07-17

    申请号：US15046648

    申请日：2016-02-18

    Applicant: CYTEC INDUSTRIES INC.

    Inventor： Eric Saly ,  Maureen Mackay ,  Matthias Rischer ,  Wolfgang Mohr ,  Lena Kurz

    IPC: A61K9/16 ,  A61K9/14 ,  A61K31/192 ,  A61K31/235 ,  A61K31/64 ,  A61K38/05

    Abstract: A particulate solid composition comprises a blend of dialkyl sulfosuccinate and a water-soluble polymer. The water-soluble polymer can be a cellulose ether, a polysaccharide, a polyvinyl alcohol homopolymer or copolymer, a polyvinyl pyrrolidone homopolymer or copolymer, a polyvinyl caprolactam polymer or copolymer, a poly(meth)acrylate, a poly(alkylene oxide) graft copolymer, or a combination thereof. The particulate solid composition is free flowing, water-soluble, and dissolves rapidly in water. It can be made by drying a solution of dialkyl sulfosuccinate and a water-soluble polymer. The particulate solid composition can be mixed with organic substances having low water solubility, for example a generic, a biologic, a biosimilar, an excipient, a nutraceutical, a medical diagnostic agent, an agricultural chemical, or a combination thereof, to form water-soluble compositions.

    DIALKYL SULFOSUCCINATE COMPOSITIONS, METHOD OF MAKING, AND METHOD OF USE
    2.
    发明申请
    DIALKYL SULFOSUCCINATE COMPOSITIONS, METHOD OF MAKING, AND METHOD OF USE 有权
    二乙基硫代磷酸酯组合物，制备方法和使用方法

    公开(公告)号：US20160317445A1

    公开(公告)日：2016-11-03

    申请号：US15046648

    申请日：2016-02-18

    Applicant: CYTEC INDUSTRIES INC.

    Inventor： Eric Saly ,  Maureen Mackay ,  Matthias Rischer ,  Wolfgang Mohr ,  Lena Kurz

    IPC: A61K9/16 ,  A61K31/64 ,  A61K38/05 ,  A61K31/192 ,  A61K31/235

    CPC classification number: A61K9/1617 ,  A61K9/145 ,  A61K9/146 ,  A61K9/1623 ,  A61K9/1635 ,  A61K9/1641 ,  A61K9/1647 ,  A61K9/1652 ,  A61K31/192 ,  A61K31/235 ,  A61K31/64 ,  A61K38/05

    Abstract: A particulate solid composition comprises a blend of dialkyl sulfosuccinate and a water-soluble polymer. The water-soluble polymer can be a cellulose ether, a polysaccharide, a polyvinyl alcohol homopolymer or copolymer, a polyvinyl pyrrolidone homopolymer or copolymer, a polyvinyl caprolactam polymer or copolymer, a poly(meth)acrylate, a poly(alkylene oxide) graft copolymer, or a combination thereof. The particulate solid composition is free flowing, water-soluble, and dissolves rapidly in water. It can be made by drying a solution of dialkyl sulfosuccinate and a water-soluble polymer. The particulate solid composition can be mixed with organic substances having low water solubility, for example a generic, a biologic, a biosimilar, an excipient, a nutraceutical, a medical diagnostic agent, an agricultural chemical, or a combination thereof, to form water-soluble compositions.

    Abstract translation: 颗粒状固体组合物包含二烷基磺基琥珀酸盐和水溶性聚合物的共混物。 水溶性聚合物可以是纤维素醚，多糖，聚乙烯醇均聚物或共聚物，聚乙烯吡咯烷酮均聚物或共聚物，聚乙烯基己内酰胺聚合物或共聚物，聚（甲基）丙烯酸酯，聚（环氧烷）接枝共聚物 ，或其组合。 颗粒状固体组合物是自由流动的，水溶性的并迅速溶于水。 可以通过干燥二烷基磺基琥珀酸盐和水溶性聚合物的溶液来制备。 颗粒状固体组合物可与具有低水溶性的有机物质混合，例如通用生物制剂，生物仿制药，赋形剂，营养药物，医学诊断剂，农药或其组合， 可溶性组合物。

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