公开(公告)号：US20250164381A1

公开(公告)日：2025-05-22

申请号：US18951489

申请日：2024-11-18

Applicant: CYTEK BIOSCIENCES, INC.

Inventor： Bing Shan ,  Ming Yan ,  Han Zhang

IPC: G01N15/149 ,  G01N15/10 ,  G01N15/14 ,  G01N15/1429 ,  G01N15/1434

Abstract: A flow cytometer or cell sorting system includes a linear array detector having a plurality of detectors; a plurality of low noise gain amplifiers respectively coupled to the plurality of detectors in the linear array detector; a plurality of analog to digital converters respectively coupled to the plurality of detectors of the linear array detector; and image reconstruction logic coupled to the plurality of analog to digital converters. The linear array detector receives the brightfield image of each cell of the plurality of biological cells and transduces the light into analog signals representative of pixels in a plurality of brightfield image lines of each cell. The plurality of analog to digital converters transduce the analog signals into digital numeric signals for each pixel. The image reconstruction logic reconstructs the plurality of brightfield image lines of each cell over time periods into a single overall brightfield image of each cell.