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公开(公告)号:US20240271149A1
公开(公告)日:2024-08-15
申请号:US18413699
申请日:2024-01-16
Inventor: Kyle B. Reynolds , Thomas Vanhercke , Anna El Tahchy , Qing Liu , Surinder S. Singh , James R. Petrie
CPC classification number: C12N15/8247 , C10G3/00 , C10L1/02 , C10L1/026 , C12N9/1029 , C12N9/16 , C12N15/52 , C10L2200/0476 , C12Y203/01158 , C12Y301/02014
Abstract: The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biofuel, and processes for producing these products, as well as plants having an increased level medium chain fatty acids such as lauric acid and myristic acid. In one particular embodiment, the present invention relates to combinations of modifications in a fatty acid thioesterase and one or more acyltransferases. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biofuel.
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公开(公告)号:US20240150779A1
公开(公告)日:2024-05-09
申请号:US18409591
申请日:2024-01-10
Applicant: Commonwealth Scientific and Industrial Research Organisation , GRAINS RESEARCH AND DEVELOPMENT CORPORATION
Inventor: James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
IPC: C12N15/82 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472
CPC classification number: C12N15/8247 , C12P7/6427 , C12P7/6432 , C12P7/6434 , C12P7/6472 , C12Y602/01003
Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
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公开(公告)号:US11913006B2
公开(公告)日:2024-02-27
申请号:US16355215
申请日:2019-03-15
Inventor: Kyle B. Reynolds , Thomas Vanhercke , Anna El Tahchy , Qing Liu , Surinder S. Singh , James R. Petrie
CPC classification number: C12N15/8247 , C10G3/00 , C10L1/02 , C10L1/026 , C12N9/1029 , C12N9/16 , C12N15/52 , C10L2200/0476 , C12Y203/01158 , C12Y301/02014
Abstract: The present invention relates to methods of producing industrial products from plant lipids, particularly from vegetative parts of plants. In particular, the present invention provides oil products such as biofuel, and processes for producing these products, as well as plants having an increased level medium chain fatty acids such as lauric acid and myristic acid. In one particular embodiment, the present invention relates to combinations of modifications in a fatty acid thioesterase and one or more acyltransferases. In an embodiment, the present invention relates to a process for extracting lipids. In another embodiment, the lipid is converted to one or more hydrocarbon products in harvested plant vegetative parts to produce alkyl esters of the fatty acids which are suitable for use as a renewable biofuel.
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公开(公告)号:US11639507B2
公开(公告)日:2023-05-02
申请号:US16353697
申请日:2019-03-14
Inventor: Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C12N15/82 , C11B1/04 , A23K10/30 , C07K14/415 , C11B3/10 , C11B3/00 , C11B7/00 , C11B3/14 , C10L1/02 , C11C3/00 , A23K20/153 , C12P7/6463 , C10G2/00 , C10L5/44 , C11B1/10
Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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公开(公告)号:US10648046B2
公开(公告)日:2020-05-12
申请号:US15642223
申请日:2017-07-05
Applicant: Commonwealth Scientific and Industrial Research Organisation , Grains Research and Development Corporation
Inventor: James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
IPC: C12N15/82
Abstract: The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ.
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公开(公告)号:US20190300894A1
公开(公告)日:2019-10-03
申请号:US16353697
申请日:2019-03-14
Inventor: Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C12N15/82 , C11B1/10 , C07K14/415 , C11B1/04 , C11B3/10 , C11B3/00 , C11B7/00 , C11B3/14 , C10L1/02 , C11C3/00 , A23K20/153 , A23K10/30 , C12P7/64 , C10G2/00
Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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公开(公告)号:US10246718B2
公开(公告)日:2019-04-02
申请号:US15293032
申请日:2016-10-13
Inventor: Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
IPC: C12N15/82 , A23K10/30 , C11B1/10 , C07K14/415 , C11B3/00 , C11B3/10 , C11B3/14 , C11B7/00 , C10L1/02 , C11C3/00 , C10G2/00 , C12P7/64 , C11B1/04 , A23K20/153 , C10L5/44
Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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公开(公告)号:US20150037457A1
公开(公告)日:2015-02-05
申请号:US14462323
申请日:2014-08-18
Inventor: Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Pal Singh , Qing Liu
CPC classification number: C10L1/19 , A23K10/30 , A23K20/153 , C07K14/415 , C10G2/00 , C10L1/026 , C10L5/44 , C10L2200/0476 , C10L2290/24 , C10L2290/544 , C11B1/04 , C11B1/06 , C11B1/10 , C11B3/001 , C11B3/006 , C11B3/02 , C11B3/10 , C11B3/14 , C11B7/0008 , C11B7/0075 , C11C3/003 , C12N15/8218 , C12N15/8247 , C12P7/6463 , Y02E50/30 , Y02E50/343
Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
Abstract translation: 本发明涉及从营养植物部分如叶,茎,根和块茎中提取脂质的方法,以及从脂质生产工业产品如烃产品。 优选的工业产品包括可与石油基燃料混合的烷基酯。
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公开(公告)号:US10246641B2
公开(公告)日:2019-04-02
申请号:US15332654
申请日:2016-10-24
Inventor: Thomas Vanhercke , James Robertson Petrie , Anna El Tahchy , Surinder Singh , Qing Liu
IPC: C07K14/415 , C10B53/02 , C10L5/44 , C11B1/00 , C12N15/82 , C12P7/64 , C11B1/10 , C11B3/00 , C11B3/10 , C11B3/14 , C11B7/00 , C11C3/00 , C10L1/02 , C10G2/00 , C07C67/48 , C01B3/22 , C10J3/82 , C12N9/10 , C01B32/40
Abstract: The present invention relates to processes for producing industrial products such as hydrocarbon products from non-polar lipids in a vegetative plant part. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
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公开(公告)号:US09976107B2
公开(公告)日:2018-05-22
申请号:US15661673
申请日:2017-07-27
Applicant: Commonwealth Scientific and Industrial Research Organisation , Grains Research and Development Corporation
Inventor: James Robertson Petrie , Anne Maree Mackenzie , Qing Liu , Pushkar Shrestha , Peter David Nichols , Susan Irene Ellis Blackburn , Maged Peter Mansour , Stanley Suresh Robert , Dion Matthew Frederick Frampton , Xue-Rong Zhou , Surinder Pal Singh , Craig Christopher Wood
CPC classification number: C11B3/006 , C12N9/0071 , C12N9/0083 , C12N9/1029 , C12N9/93 , C12N15/52 , C12N15/8202 , C12N15/8205 , C12N15/8216 , C12N15/8218 , C12N15/8234 , C12N15/8247 , C12N15/8257 , C12P7/6427 , C12P7/6436 , C12P7/6463 , C12P7/6472 , C12Y114/00 , C12Y114/19 , C12Y114/19003 , C12Y602/01003
Abstract: The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desaturase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids. In particular, the present invention provides ω3 destaurases, Δ5 elongases and Δ6 desaturases with novel activities. Also provided are methods and DNA constructs for transiently and/or stably transforming cells, particularly plant cells, with multiple genes.
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