公开(公告)号：US12180386B2

公开(公告)日：2024-12-31

申请号：US16900332

申请日：2020-06-12

Applicant: Covalon Technologies Inc.

Inventor： Vyacheslav Dudnyk ,  Valerio DiTizio

IPC: C09D175/04 ,  A61L29/04 ,  A61L29/08 ,  A61L29/16

Abstract: Provided herein is a method of grafting a polymeric coating onto a first side of a wall of a device. The method comprises: applying an initiator substantially only to a second side of the wall; applying a coating composition to the first side of the wall; and graft-polymerizing the coating composition.

公开(公告)号：US08628800B2

公开(公告)日：2014-01-14

申请号：US13750872

申请日：2013-01-25

Applicant: Covalon Technologies, Inc.

Inventor： Valerio DiTizio ,  Frank DiCosmo ,  Yuehua Xiao

IPC: A61K9/70

CPC classification number: A61K47/42 ,  A61K9/7007 ,  A61K47/10 ,  A61K47/36 ,  A61L15/225 ,  A61L15/325 ,  A61L15/425 ,  A61L31/041 ,  A61L31/045 ,  A61L31/146 ,  C08L5/00 ,  C08L5/04 ,  C08L5/08 ,  C08L71/00 ,  C08L89/00 ,  C08L89/06 ,  C08L2205/02 ,  C08L2666/26 ,  C08L2666/14 ,  C08L2666/02

Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.

Abstract translation: 本发明是基本上不粘的弹性明胶基体。 基质既不与伤口，组织和器官粘合，也具有弹性，使其柔韧。 基质是蛋白质，聚合物，交联剂和任选的增塑剂的冻干混合物。 本发明还提供了制造非粘性弹性明胶基质的方法。

公开(公告)号：US20130137780A1

公开(公告)日：2013-05-30

申请号：US13750872

申请日：2013-01-25

Applicant: COVALON TECHNOLOGIES, INC.

Inventor： Valerio DiTizio ,  Frank DiCosmo ,  Yuehua Xiao

IPC: A61K47/42

CPC classification number: A61K47/42 ,  A61K9/7007 ,  A61K47/10 ,  A61K47/36 ,  A61L15/225 ,  A61L15/325 ,  A61L15/425 ,  A61L31/041 ,  A61L31/045 ,  A61L31/146 ,  C08L5/00 ,  C08L5/04 ,  C08L5/08 ,  C08L71/00 ,  C08L89/00 ,  C08L89/06 ,  C08L2205/02 ,  C08L2666/26 ,  C08L2666/14 ,  C08L2666/02

Abstract: The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.

Abstract translation: 本发明是基本上不粘的弹性明胶基体。 基质既不与伤口，组织和器官粘合，也具有弹性，使其柔韧。 基质是蛋白质，聚合物，交联剂和任选的增塑剂的冻干混合物。 本发明还提供了制造非粘性弹性明胶基质的方法。

公开(公告)号：US20210299017A1

公开(公告)日：2021-09-30

申请号：US17213783

申请日：2021-03-26

Applicant: Covalon Technologies Inc.

Inventor： Valerio DiTizio ,  Brian Pedlar ,  Agnesa Shala-Lawrence ,  Vyacheslav Dudnyk ,  Genevieve Conant

IPC: A61K8/41 ,  A61Q17/00 ,  A61L2/18

Abstract: An antimicrobial composition is described herein. The composition comprises an antimicrobial agent, a sequestering agent, a release agent, and an optional dispersing agent. Hand sanitizers and sprays comprising the composition are also described, along with related methods of sanitizing items, such as hands, surfaces, and personal protective equipment.