公开(公告)号：US20210018465A1

公开(公告)日：2021-01-21

申请号：US17030285

申请日：2020-09-23

Applicant: DH Technologies Development PTE Ltd.

Inventor： David D. Y. Chen ,  Chang Liu

IPC: G01N27/447 ,  G01N30/00 ,  G01N1/40

Abstract: Provided is the processing of sample fluids containing one or more analytes of interest and to methods and devices for separating and/or purifying components of a sample fluid using electric and hydrodynamic forces. Though the fluid processing systems and methods are generally described herein as applied to microfluidics, it will be appreciated that the fluid processing systems may process any fluid volume suitable for use in embodiments described herein. Y-shaped and multiple-branched shaped 2-D EFD devices have been used to separate and/or purify one or more analytes from a mixture. Systems and methods in accordance with various aspects of the present teachings utilize hydrodynamic pressure (e.g., using a pump) to drive the sample liquid from the sample inlet to the separation stream, and can, in some aspects, provide improved control of the movement of the analytes, improved processing times, and decreased buffer depletion.

公开(公告)号：US20170212076A1

公开(公告)日：2017-07-27

申请号：US15329268

申请日：2015-07-29

Applicant: DH Technologies Development PTE Ltd.

Inventor： David D. Y. Chen ,  Chang Liu

IPC: G01N27/447 ,  G01N1/40 ,  G01N30/00

CPC classification number: G01N27/44765 ,  B01L3/502715 ,  G01N1/40 ,  G01N27/44743 ,  G01N27/44769 ,  G01N27/44791 ,  G01N30/0005 ,  G01N2001/4038

Abstract: Provided is the processing of sample fluids containing one or more analytes of interest and to methods and devices for separating and/or purifying components of a sample fluid using electric and hydrodynamic forces. Though the fluid processing systems and methods are generally described herein as applied to microfluidics, it will be appreciated that the fluid processing systems may process any fluid volume suitable for use in embodiments described herein. Y-shaped and multiple-branched shaped 2-D EFD devices have been used to separate and/or purify one or more analytes from a mixture. Systems and methods in accordance with various aspects of the present teachings utilize hydrodynamic pressure (e.g., using a pump) to drive the sample liquid from the sample inlet to the separation stream, and can, in some aspects, provide improved control of the movement of the analytes, improved processing times, and decreased buffer depletion.