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公开(公告)号：US11499142B2
公开(公告)日：2022-11-15
申请号：US16463074
申请日：2017-11-23
Applicant: DSM IP Assets B.V.
Inventor： Loes Elizabeth Bevers , Maaike Appeldoorn , Margot Elisabeth Francoise Schooneveld-Bergmans , Herman Jan Pel
IPC: C12N9/00 , C12N9/42 , C12N9/02 , C12N9/26 , C12P19/00 , C12N9/24 , C12P7/10 , C12P19/02 , C12P19/14 , C12N9/18
Abstract: The application relates to an enzyme composition, a process for the preparation thereof and the use of the enzyme composition in enzymatic hydrolysis.
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Patent Agency Ranking
公开(公告)号：US09738890B2
公开(公告)日：2017-08-22
申请号：US14386354
申请日：2013-03-27
Applicant: DSM IP ASSETS B.V.
Inventor： Johannes Andries Roubos , Herman Jan Pel , Bernard Meijrink
CPC classification number: C12N15/1024 , C12N15/66 , C12N15/90 , C12N2800/30 , C12N2800/40 , C12N2800/50 , C12N2800/80
Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via cleavage sites, thereby to prepare two or more standardized expression cassettes.
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公开(公告)号：US20150050696A1
公开(公告)日：2015-02-19
申请号：US14386354
申请日：2013-03-27
Applicant: DSM IP ASSETS B.V.
Inventor： Johannes Andries Roubos , Herman Jan Pel , Bernard Meijrink
IPC: C12N15/10
CPC classification number: C12N15/1024 , C12N15/66 , C12N15/90 , C12N2800/30 , C12N2800/40 , C12N2800/50 , C12N2800/80
Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via cleavage sites, thereby to prepare two or more standardized expression cassettes.
Abstract translation: 本发明涉及一种基于限制酶消化和通过切割位点连接的方法，从而制备两个或多个标准化表达盒。
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公开(公告)号：US20150197760A1
公开(公告)日：2015-07-16
申请号：US14408089
申请日：2013-06-17
Applicant: DSM IP ASSETS B.V.
Inventor： Alrik Pieter Los , Wilbert Herman Marie Heijne , Herman Jan Pel , Robbertus Antonius Damveld , Brenda Vonk
CPC classification number: C12N15/80 , C12N9/18 , C12N9/2408 , C12N9/2428 , C12N9/2434 , C12P1/02 , C12P21/02
Abstract: The present invention relates to isolated Rasamsonia promoter DNA sequences, to DNA constructs, vectors, and host cells comprising these promoters in operative association with coding sequences. The present invention also relates to methods for expressing a gene and/or producing a biological compound using the new promoters isolated. The present invention also relates to methods for altering the transcription level and/or regulation of an endogenous gene using the new promoter of the invention.
Abstract translation: 本发明涉及分离的Rasamsonia启动子DNA序列，涉及包含这些启动子的DNA构建体，载体和宿主细胞，其与编码序列有效结合。 本发明还涉及使用分离的新启动子来表达基因和/或生产生物化合物的方法。 本发明还涉及使用本发明的新启动子改变内源基因的转录水平和/或调节的方法。
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公开(公告)号：US20170314011A1
公开(公告)日：2017-11-02
申请号：US15648983
申请日：2017-07-13
Applicant: DSM IP ASSETS B.V.
Inventor： Johannes Andries ROUBOS , Herman Jan Pel , Bernard Meijrink
CPC classification number: C12N15/1024 , C12N15/66 , C12N15/90 , C12N2800/30 , C12N2800/40 , C12N2800/50 , C12N2800/80
Abstract: The present invention relates to a method based on the use of restriction enzyme digestion and ligation via the cleavage sites, thereby to prepare two or more standardized expression cassettes.
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公开(公告)号：US09322045B2
公开(公告)日：2016-04-26
申请号：US14249587
申请日：2014-04-10
Applicant: DSM IP ASSETS B.V.
Inventor： Noël Nicolaas Maria Elisabeth Van Peij , Herman Jan Pel , Thibaut José Wenzel , Adriana Marina Riemens , Ilse De Lange
CPC classification number: C12P21/00 , A01K2267/01 , C12N9/2428 , C12N15/80 , C12N15/8509 , C12N15/902
Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.
Abstract translation: 本发明涉及用于生产感兴趣的化合物的重组宿主细胞。 本发明还涉及生产这种宿主细胞的方法。 本发明还涉及生产感兴趣的化合物。 本发明还涉及分离的多核苷酸和包含所述多核苷酸的载体和宿主细胞。
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