BIOINTERFACE MEMBRANES INCORPORATING BIOACTIVE AGENTS
    7.
    发明申请
    BIOINTERFACE MEMBRANES INCORPORATING BIOACTIVE AGENTS 审中-公开
    生物体膜生物活性剂

    公开(公告)号:US20140275900A1

    公开(公告)日:2014-09-18

    申请号:US14290842

    申请日:2014-05-29

    Applicant: DexCom, Inc.

    Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.

    Abstract translation: 一种用于可植入装置的生物界面膜,其包括不可再吸收的固体部分,其具有适于在体内支持组织向内生长的多个相互连接的空腔,以及并入生物界面膜中并适于修饰组织反应的生物活性剂。 可以选择生物活性剂以诱导血管形成和/或预防体内阻隔细胞层形成,并且当与其中溶质被输送穿过装置 - 组织界面的可植入装置一起使用时是有利的。

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