公开(公告)号：US20250072926A1

公开(公告)日：2025-03-06

申请号：US18954086

申请日：2024-11-20

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Bezalel Haberman-Browns ,  Allen Jeong Keel ,  Mazen Saadi Albaghdadi ,  Gil Senesh ,  Yehoshua Strauss ,  Gideon Meyer-Brodnitz ,  Michael Lis ,  Atiya Makhdoom Ahmad ,  Zachary Christopher Berwick ,  Tal Reich

IPC: A61B17/32 ,  A61B17/00 ,  A61B17/3209 ,  A61M25/00

Abstract: Examples of transection devices are disclosed. One example includes an elongated body having a U-shaped notch, wherein the U-shaped notch includes a wall surface extending from a surface of the elongated body and an upper extension extending from the wall surface substantially parallel with the longitudinal axis of the elongated body. An incision member located in the U-shaped notch preferably extends from the elongated body toward the extension of the U-shaped notch at an angle. The incision member is well suited for cutting pericardial tissue as it passes through the U-shaped notch.

公开(公告)号：US12064348B2

公开(公告)日：2024-08-20

申请号：US18311880

申请日：2023-05-03

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Gil Senesh ,  Jeanette Jasmine Corona Kelly ,  Sandip Vasant Pawar

IPC: A61F2/24 ,  A61F2/00

CPC classification number: A61F2/2418 ,  A61F2/0077 ,  A61F2210/0076 ,  A61F2250/001

Abstract: A prosthetic heart valve including a frame, leaflet structure, and sealing member disposed around an outer surface of the frame is disclosed. As one example, the sealing member includes a knitted fabric layer, the knitted fabric layer comprising a base layer forming an inner surface of the knitted fabric layer, where the base layer has a mesh-like structure. The knitted fabric layer further comprises a plush outer surface comprising a plurality of pile yarns knit into loops and that extend outward from the base layer.

公开(公告)号：US20240216139A1

公开(公告)日：2024-07-04

申请号：US18607271

申请日：2024-03-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nicholas Brandon Aders ,  Kristen Hicks ,  Gil Senesh ,  Michael R. Bialas ,  Tung T. Le ,  Sean Chow ,  Thanh Huy Le

IPC: A61F2/24 ,  B23P11/00 ,  A61F2/95

CPC classification number: A61F2/2433 ,  B23P11/005 ,  A61F2/9524 ,  A61F2240/001 ,  A61F2250/0039

Abstract: Devices and methods for crimping a prosthetic heart valve onto a delivery device are described. In some embodiments, valves are crimped over an inflatable balloon and between proximal and distal shoulders mounted on a shaft inside the balloon. Crimping methods can include multiple compression steps with the valve located in different axial positions relative to the crimping jaws at each different step. In some methods, the valve may extend partially outside of the crimping jaws during certain crimping steps, such that the crimping force is only applied to the part of the valve that is inside the jaws. Exemplary crimping devices can include two or more adjacent sets of jaws that close down to different inner diameters, such that different parts of a valve get compressed to different outer diameters at the same time during a single crimping step.

公开(公告)号：US11872125B2

公开(公告)日：2024-01-16

申请号：US17659577

申请日：2022-04-18

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24 ,  A61F2/90

CPC classification number: A61F2/2418 ,  A61F2/2409 ,  A61F2/2433 ,  A61F2/2412 ,  A61F2/90 ,  A61F2220/0075 ,  A61F2230/0023 ,  A61F2230/0052 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069 ,  A61F2310/00017 ,  A61F2310/00029 ,  A61F2310/00059

Abstract: A system can include a delivery catheter comprising a balloon and an implantable prosthetic heart valve. The prosthetic valve can have a plastically expandable and compressible unitary frame comprising first, second, and third rows of angled struts that define two circumferentially extending rows of diamond-shaped cells that extend continuously around the frame, and a valvular structure comprising a plurality of leaflets. A cusp edge portion of each leaflet is connected to the frame by a skirt that is connected to and disposed between the frame and the cusp edge portions of the leaflets, the skirt being connected to consecutive struts in the first, second, and third rows of struts with sutures. The compressed prosthetic heart valve can be mounted around the balloon and radially expanded to the expanded configuration with the balloon inside a patient's body.

公开(公告)号：US20230277313A1

公开(公告)日：2023-09-07

申请号：US18316942

申请日：2023-05-12

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2/2409 ,  A61F2250/0069 ,  A61F2250/0003 ,  A61F2230/0052 ,  A61F2230/0023 ,  A61F2/2412 ,  A61F2/90

Abstract: A prosthetic heart valve can include a radially expandable and compressible frame having an inflow end, an outflow end, and a plurality of struts. The prosthetic valve can further include a valvular structure comprising a plurality of leaflets, each leaflet comprising a coaptation edge portion and a cusp edge portion. The cusp edge portion of each leaflet can be folded toward the outflow end of the frame along a bending axis and a reinforcing member extends along an outflow surface of the cusp edge portion along the bending axis. The prosthetic heart valve can include a plurality of connecting skirts, each disposed between the cusp edge portion of an adjacent leaflet and the frame. First stitching secures the reinforcing member and the connecting skirts to the cusp edge portions and second stitching secures the connecting skirts to selected struts of the frame.

公开(公告)号：US11096781B2

公开(公告)日：2021-08-24

申请号：US15664430

申请日：2017-07-31

Applicant: Edwards Lifesciences Corporation

Inventor： Nikolay Gurovich ,  Michael Bukin ,  Elena Sherman ,  Tamir S. Levi ,  Ziv Yohanan ,  Gil Senesh ,  Dikla Kersh ,  Alexey M. Tsypenyuk ,  Waina Michelle Chu ,  Alexander Barash

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame. The prosthetic heart valve can also include a sealing member mounted on the frame and having an inner layer and an outer layer. At least the outer layer is mounted on the outside of the frame, and the inner layer covers at least the openings in the frame between adjacent cusp portions of adjacent leaflets and the inner layer does not cover one or more openings in the frame at locations facing the outflow surfaces of the leaflets to permit retrograde blood to flow through the one or more uncovered openings in the frame and into space between the outer layer and the frame.

公开(公告)号：US12257149B2

公开(公告)日：2025-03-25

申请号：US18478083

申请日：2023-09-29

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Arvin T. Chang ,  Yair A. Neumann ,  Gil Senesh ,  Hernan Altman ,  Scott Louis Pool ,  Hannah Gibson ,  Amanda Kristine Anderson White ,  Peter Phong Tran ,  Ly Th Phan

IPC: A61F2/24

Abstract: A delivery apparatus for a medical device can include a handle, a shaft, a plurality of sleeves, and a suture. The shaft includes a proximal end portion coupled to the handle and is configured to be disposed outside of a patient's body during an implantation procedure and a distal end portion configured to be disposed inside a patient's body during the implantation procedure. Each of the sleeves includes a connection portion coupled to the distal end portion of the shaft and a receiving portion configured to receive an apex of a stent or a prosthetic heart valve. The suture extends through the shaft and the sleeves and is configured for releasably securing the stent or the prosthetic heart valve to the receiving portions of the sleeves.

公开(公告)号：US12161551B2

公开(公告)日：2024-12-10

申请号：US16551634

申请日：2019-08-26

Applicant: Edwards Lifesciences Corporation

Inventor： Michael R. Bialas ,  Robert James Gerard ,  Gil Senesh

IPC: A61F2/24 ,  A61B5/107

Abstract: A method of implanting a prosthetic heart valve includes selecting a prosthetic heart valve. The selected prosthetic heart valve has a nominal diameter that is greater than a native annulus diameter of a native annulus by up to forty percent. The method further comprises compressing the selected prosthetic heart valve to a radially compressed configuration in which the selected prosthetic heart valve has a first diameter that is less than the nominal diameter, positioning the selected prosthetic heart valve within the native annulus, and expanding the selected prosthetic heart valve from the radially compressed configuration to a radially expanded configuration in which the selected prosthetic heart valve has a second diameter which is less than the nominal diameter by up to ten percent and which is greater than the first diameter.

公开(公告)号：US20240261089A1

公开(公告)日：2024-08-08

申请号：US18614255

申请日：2024-03-22

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael R. Bialas ,  Kristen Hicks ,  Michael C. Murad ,  Gil Senesh ,  Quang Ngoc Vu ,  Gonzalo German Angelico ,  Carla Susana Cerqueira ,  Victoria Mariko Low ,  Andrea Fernandez ,  Karl J. Britzman ,  Shannon Nicole Ash (formerly Hoye) ,  Haley Nicole Whitehead

IPC: A61F2/24 ,  A61B50/30 ,  A61F2/95 ,  A61F2/958 ,  A61M25/10

CPC classification number: A61F2/24 ,  A61B50/30 ,  A61F2/2418 ,  A61F2/2436 ,  A61M25/10 ,  A61F2/2433 ,  A61F2/9517 ,  A61F2002/9583 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0002 ,  A61F2250/0098

Abstract: Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.

公开(公告)号：US20240024106A1

公开(公告)日：2024-01-25

申请号：US18477329

申请日：2023-09-28

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael R. Bialas ,  Robert James Gerard ,  Gil Senesh

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2412 ,  A61F2/2445 ,  A61F2/2472 ,  A61F2/2409 ,  A61F2/2439 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2250/0069 ,  A61B5/1075

Abstract: A method of implanting a prosthetic heart valve includes determining from a set of expandable prosthetic heart valves a first prosthetic heart valve. The first prosthetic heart valve has a first nominal diameter less than a native annulus diameter. The method further includes determining a first suggested expanded diameter for the first prosthetic heart valve based on the native annulus diameter, wherein the first suggested expanded diameter is greater than the first nominal diameter, and determining a pressure gradient across the first prosthetic heart valve at the first suggested expanded diameter based at least in part on pressure values from hemodynamic data of the first prosthetic heart valve. The method further includes selecting the prosthetic heart valve from the set of expandable prosthetic heart valves with the suggested expanded diameter resulting in the lowest pressure gradient for implantation from the set of prosthetic heart valves.