公开(公告)号：US20230296617A1

公开(公告)日：2023-09-21

申请号：US17904503

申请日：2021-02-09

Applicant: East China University of Science and Technology

Inventor： Yi Yang ,  Yuzheng Zhao ,  Chenxia Zhang ,  Li Huang ,  Yejun Zou ,  Xie Li ,  Shuning Liu

IPC: G01N33/68 ,  G01N33/58 ,  C12N15/63

CPC classification number: G01N33/6812 ,  G01N33/582 ,  C12N15/63

Abstract: Disclosed is a tryptophan optical probe, a preparation method therefor and the use thereof. Disclosed is an optical probe, comprising a tryptophan-sensitive polypeptide or a functional variant thereof and an optically active polypeptide or a functional variant thereof, wherein the optically active polypeptide or the functional variant thereof is located in the sequence of the tryptophan-sensitive polypeptide or the functional variant thereof. Furthermore, disclosed are a method for preparing the above-mentioned probe and the use thereof in the detection of tryptophan.