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    FORMATION OF PARTICLES INCLUDING AGENTS
    2.
    发明申请
    FORMATION OF PARTICLES INCLUDING AGENTS 有权

    公开(公告)号：US20210322317A1

    公开(公告)日：2021-10-21

    申请号：US17364770

    申请日：2021-06-30

    Applicant: Elektrofi, Inc.

    Inventor： Chase Spenser Coffman ,  Lyndon Fitzgerald Charles, JR. ,  Paul Brown ,  Daniel Benjamin Dadon ,  Lisa Liu ,  Cory Robinson ,  Dale Arlington Thomas, III

    IPC: A61K9/14 ,  B01J2/06

    Abstract: The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

    Formation of particles including agents
    4.
    发明授权
    Formation of particles including agents 有权

    公开(公告)号：US12263249B2

    公开(公告)日：2025-04-01

    申请号：US17364770

    申请日：2021-06-30

    Applicant: Elektrofi, Inc.

    Inventor： Chase Spenser Coffman ,  Lyndon Fitzgerald Charles, Jr. ,  Paul Brown ,  Daniel Benjamin Dadon ,  Lisa Liu ,  Cory Robinson ,  Dale Arlington Thomas, III

    IPC: A61K9/14 ,  B01J2/06

    Abstract: The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

    Electrospraying formation of particles including agents
    5.
    发明授权
    Electrospraying formation of particles including agents 有权

    公开(公告)号：US11077059B2

    公开(公告)日：2021-08-03

    申请号：US16633097

    申请日：2018-07-25

    Applicant: Elektrofi, Inc.

    Inventor： Chase Spenser Coffman ,  Lyndon Fitzgerald Charles, Jr. ,  Paul Brown ,  Daniel Benjamin Dadon ,  Lisa Liu ,  Cory Robinson ,  Dale Arlington Thomas, III

    IPC: A61K9/14 ,  B01J2/06

    Abstract: The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

    FORMATION OF PARTICLES INCLUDING AGENTS
    7.
    发明申请
    FORMATION OF PARTICLES INCLUDING AGENTS 审中-公开

    公开(公告)号：US20200253875A1

    公开(公告)日：2020-08-13

    申请号：US16633097

    申请日：2018-07-25

    Applicant: Elektrofi, Inc.

    Inventor： Chase Spenser Coffman ,  Lyndon Fitzgerald Charles, Jr. ,  Paul Brown ,  Daniel Benjamin Dadon ,  Lisa Liu ,  Cory Robinson ,  Dale Arlington Thomas, III

    IPC: A61K9/14 ,  B01J2/06

    Abstract: The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and/or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

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