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    UNCOUPLED CELL CULTURE METHOD
    1.
    发明申请
    UNCOUPLED CELL CULTURE METHOD 审中-公开
    未解密的细胞培养方法

    公开(公告)号：US20160145668A1

    公开(公告)日：2016-05-26

    申请号：US14904381

    申请日：2014-07-15

    Applicant: FERMENTALG

    Inventor： Patrice GARNIER ,  Julien PAGLIARDINI ,  Pierre CALLEJA

    IPC: C12P23/00 ,  C12P7/64

    CPC classification number: C12P23/00 ,  A01G33/00 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N13/00 ,  C12P7/6427 ,  C12P7/6472

    Abstract: Disclosed is a method for producing biomass by culturing cells in mixotrophic conditions, in particular in the presence of discontinuous and/or variable lighting conditions, and/or in heterotrophic conditions, making it possible to obtain an increase in both the cellular concentration and the production of molecules of interest.

    Abstract translation: 公开了通过在混合营养条件下培养细胞，特别是在不连续和/或可变照明条件存在下和/或异养条件下生产生物质的方法，使得可以获得细胞浓度和生产两者的增加 的感兴趣的分子。

    REACTOR WITH INTEGRATED ILLUMINATION
    2.
    发明申请
    REACTOR WITH INTEGRATED ILLUMINATION 审中-公开
    具有集成照明的反应器

    公开(公告)号：US20160046899A1

    公开(公告)日：2016-02-18

    申请号：US14784241

    申请日：2014-04-11

    Applicant: FERMENTALG ,  PIERRE GUERIN

    Inventor： Patrice GARNIER ,  Francois GODART ,  Pierre CALLEJA ,  Samuel GIRAUD ,  Doru FELEZEU

    IPC: C12M1/00 ,  C12M1/06

    CPC classification number: C12M31/10 ,  C12M21/02 ,  C12M27/02 ,  C12M27/20

    Abstract: A reactor includes a tank intended to contain a mass to be treated, for example formed from microorganisms, an assembly that rotates about an axis to ensure stirring of this mass, and a plurality of illumination sources to assist the treatment of this mass. The tank has an inner wall with plates fixed thereto, whose planes are oriented towards the axis of the rotating assembly and parallel to same, so as to prevent the formation of a vortex within the mass under the action of the rotating assembly; the illumination sources are carried by the plates, being encapsulated, with at least the part of the plates that carries them, in a material compatible with the mass treated and in a thickness that allows light to be diffused into the tank. This configuration may be scaled, while keeping the ratio of the illumination surface relative to the tank volume approximately constant.

    Abstract translation: 反应器包括用于容纳例如由微生物形成的待处理物料的罐，围绕轴旋转以确保搅拌该物料的组件以及多个照明源以协助处理该物料。 罐具有固定有板的内壁，其平面朝向旋转组件的轴线定向并平行于其，以防止在旋转组件的作用下在质量块内形成涡流; 照明源由板承载，至少部分装有板的板，以与所处理的物质相适应的材料和允许光扩散到罐中的厚度进行封装。 这种配置可以缩放，同时保持照明表面相对于容器容积的比率近似恒定。

    METHOD FOR CULTURING MICROALGAE OF THE AURANTIOCHYTRIUM GENUS IN A CULTURE MEDIUM WITHOUT CHLORIDE AND WITHOUT SODIUM FOR THE PRODUCTION OF DHA
    6.
    发明申请
    METHOD FOR CULTURING MICROALGAE OF THE AURANTIOCHYTRIUM GENUS IN A CULTURE MEDIUM WITHOUT CHLORIDE AND WITHOUT SODIUM FOR THE PRODUCTION OF DHA 审中-公开
    用于培养不含氯离子的培养基中的芳香化合物微生物的方法，用于生产DHA的方法

    公开(公告)号：US20170016036A1

    公开(公告)日：2017-01-19

    申请号：US15301091

    申请日：2015-04-03

    Applicant: FERMENTALG

    Inventor： Pierre CALLEJA ,  Julien PAGLIARDINI ,  Olivier CAGNAC ,  Francois GODART

    IPC: C12P7/64

    CPC classification number: C12P7/6427 ,  A23D9/00 ,  A23K20/158 ,  A23K50/80 ,  A23L33/115 ,  C11B1/10 ,  C12N1/12

    Abstract: A method for culturing a protist of the Aurantiochytrium mangrovei genus. The genus is characterized genetically and by virtue of the lipid profile thereof. The method makes it possible to obtain a high biomass yield and a lipid, and more particularly docosahexaenoic acid (DHA), enrichment of the protists thus cultured. The development of a culture medium allows the production, at high cell density, of a DHA-rich protest of the Aurantiochytrium mangrovei genus. The medium is chemically defined at low sodium ion (Na+) and chloride ion (Cl−) content.

    Abstract translation: 一种培养红曲霉属的原始生物的方法。 该属的遗传特征及其脂质谱。 该方法可以获得高生物质产量和脂质，特别是二十二碳六烯酸（DHA），这样培养的原生生物的富集。 培养基的开发允许在高细胞密度下生产红曲霉属的富含DHA的抗体。 该介质在低钠离子（Na +）和氯离子（Cl-）含量下化学定义。

    NOVEL STRAIN OF AURANTIOCHYTRIUM
    10.
    发明申请
    NOVEL STRAIN OF AURANTIOCHYTRIUM 审中-公开
    新亚洲新菌株

    公开(公告)号：US20160153021A1

    公开(公告)日：2016-06-02

    申请号：US14904369

    申请日：2014-07-15

    Applicant: FERMENTALG

    Inventor： Francois GODART ,  Julien PAGLIARDINI ,  Cyril ROLS ,  Pierre CALLEJA

    IPC: C12P23/00 ,  C12P7/64

    CPC classification number: C12P23/00 ,  C12N1/12 ,  C12N13/00 ,  C12P7/6427 ,  C12P7/6472 ,  C12R1/89

    Abstract: Disclosed are novel strains of protists belonging to the Aurantiochytrium genus that allow the high yield production of lipids and carotenoids, in particular docosahexaenoic acid (DHA) and canthaxanthin and/or astaxanthin, in mixotrophic mode, in particular, using variable and/or discontinuous provision of light, in particular in the form of flashes.

    Abstract translation: 公开了属于Aurantiochytrium属的新生抗原素菌株，其特别是使用可变和/或不连续条件，允许在混合营养模式下高产量产生脂质和类胡萝卜素，特别是二十二碳六烯酸（DHA）和角黄素和/或虾青素 光，特别是以闪光的形式。

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