公开(公告)号：US20200040039A1

公开(公告)日：2020-02-06

申请号：US16577517

申请日：2019-09-20

Applicant: FUJIFILM Corporation

Inventor： Masaaki INOUE ,  Takashi TAMURA ,  Yuji YOSHIMITSU ,  Takahiro HOHSAKA ,  Takayoshi WATANABE

IPC: C07K7/64

Abstract: An object of the present invention is to provide a novel cyclic peptide compound excellent in cell membrane permeability, a method for producing the same, a composition for screening use, and a method for selecting a cyclic peptide compound that binds to a target substance. According to the present invention, a peptide compound represented by Formula (1) or a salt thereof is provided. In the formula, the symbols have the meanings as defined in the specification of the present application.

公开(公告)号：US20240247253A1

公开(公告)日：2024-07-25

申请号：US18597128

申请日：2024-03-06

Applicant: FUJIFILM Corporation

Inventor： Ken MATSUI ,  Jo TOMINAGA ,  Shiori KIHARA ,  Takahiro HOSAKA ,  Takayoshi WATANABE

IPC: C12N15/10

CPC classification number: C12N15/1037 ,  C12N15/1065

Abstract: Provided is a production method of a polypeptide in which expressing a polypeptide as a tagged polypeptide is included, the method including expressing the tagged polypeptide from a nucleic acid containing a base sequence encoding a tag consisting of an amino acid sequence set forth in SEQ ID NO: 1, which is arranged immediately after a start codon, and a base sequence encoding a polypeptide that is arranged in-frame downstream of the base sequence encoding the tag,
SEQ ID NO: 1: Val-Lys-Lys-(Xaa)n. (Xaa)n is a chain of n pieces of any amino acids, where n is an integer of 1 to 8, and the amino acids constituting (Xaa)n may be one type of amino acid or two or more types of amino acids.

公开(公告)号：US20240229015A1

公开(公告)日：2024-07-11

申请号：US18611981

申请日：2024-03-21

Applicant: FUJIFILM Corporation

Inventor： Yukiko ISHII ,  Jo TOMINAGA ,  Shiori KIHARA ,  Takahiro HOHSAKA ,  Takayoshi WATANABE

IPC: C12N15/10 ,  C12N15/113

CPC classification number: C12N15/1062 ,  C12N15/1044 ,  C12N15/1096 ,  C12N15/113

Abstract: Provided are a tRNA obtained by modifying a tRNA for tryptophan of Mycoplasma pneumoniae, the tRNA including a UUA as an anticodon to pair with a UAA codon, and an application of the tRNA.