公开(公告)号：US12084427B2

公开(公告)日：2024-09-10

申请号：US17740275

申请日：2022-05-09

Applicant: Fudan University

Inventor： Fener Chen ,  Liangchuan Lai ,  Baijun Ye ,  Meifen Jiang

IPC: C07D401/12 ,  B01J4/00 ,  B01J8/02

CPC classification number: C07D401/12 ,  B01J4/001 ,  B01J4/008 ,  B01J8/02

Abstract: Disclosed is a method of continuously preparing N,N-Bis(2,2,6,6-tetramethyl-4-piperidyl)-1,6-hexamethylenediamine, which relates to chemical engineering. The Pt/C catalyst and the quartz sand are mixed uniformly and loaded to the continuous-flow fixed-bed reactor. Then, hydrogen gas and a substrate solution containing 2,2,6,6-tetramethyl-4-piperidinone and 1,6-hexanediamine are simultaneously fed to the micro-mixer and the continuous-flow fixed-bed reactor in sequence to undergo a continuous catalytic reductive amination to obtain the N,N-Bis(2,2,6,6-tetramethyl-4-piperidyl)-1,6-hexamethylenediamine.