公开(公告)号：US11213605B2

公开(公告)日：2022-01-04

申请号：US16875554

申请日：2020-05-15

Applicant: GREENBONE ORTHO S.P.A.

Inventor： Anna Tampieri ,  Simone Sprio ,  Andrea Ruffini

IPC: A61L27/12 ,  A61L27/36 ,  A61L27/56

Abstract: The present disclosure relates to a hydroxyapatite obtained from porous wood, having high compressive strength and dimensions suitable for clinical applications. The porous wood has a porosity of between about 60% and about 95%, said porosity being measured after subjecting the wood to a step of pyrolysis, and is selected from among rattan, pine, abachi, balsa, sipo, oak, rosewood, kempas and walnut wood. The hydroxyapatite may be substituted with one or more ions such as magnesium, strontium, silicon, titanium, carbonate, potassium, sodium, silver, gallium, copper, iron, zinc, manganese, europium, gadolinium. Also disclosed is a bone substitute comprising hydroxyapatite obtained from porous wood. The bone substitute is utilized for the substitution and regeneration of a bone or a bone portion, preferably for bones subjected to mechanical loads, such as long bones of the leg and arm, preferably the tibia, fibula, femur, humerus and radius. The invention relates also to a process for manufacturing a biomorphic hydroxyapatite scaffold from wood.

公开(公告)号：US12157103B2

公开(公告)日：2024-12-03

申请号：US17267301

申请日：2019-07-26

Applicant: GREENBONE ORTHO S.P.A.

Inventor： Lorenzo Giuseppe Pradella ,  Alberto Ballardini ,  Lorenzo Santi ,  Anna Tampieri ,  Simone Sprio ,  Andrea Ruffini

IPC: B01J3/03 ,  B01J3/00 ,  B01J3/02 ,  B01J3/04 ,  B01J19/00 ,  B01J19/18 ,  C01B21/064 ,  C01B21/068 ,  C01B21/072 ,  C01B21/076 ,  C01F11/18 ,  C01G23/00 ,  F27B5/04 ,  F27B5/16 ,  F27D5/00 ,  F27D7/02 ,  F27D7/04 ,  F27D7/06

Abstract: A system for chemical transformation of 3D state materials is disclosed wherein, a reaction group having a main body arranged to shape a reaction chamber in which a component configured to support a sample of 3D state arranged to be chemically transform is expected. The system further includes an oven arranged to heat the reaction chamber and a GAS supply group arranged to release a first gas in the reaction chamber and/or a casing component, inside the main body, which has a chemical agent suitable for releasing a second gas into the reaction chamber. The main body has at least two turbines arranged to converge into the reaction chamber, the first and/or the second gas on the samples. The invention relates also to a method for chemical transformation of 3D state materials.