公开(公告)号：US12216135B2

公开(公告)日：2025-02-04

申请号：US18489516

申请日：2023-10-18

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  HongRan Peng ,  David Aaron Buse ,  David H. Combs

IPC: G01N35/04 ,  B01L3/00 ,  B01L9/06 ,  B65G43/08 ,  B65G47/90 ,  G01N35/00 ,  G01N35/10

Abstract: A receptacle delivery system that includes a rail extending between first and second locations of an instrument and a carriage configured to move on the rail between the first and second locations of the instrument. The carriage includes a bracket having opposed first and second sidewalls and a base extending between the first and second sidewalls, where the carriage is configured to support a receptacle. The carriage further includes a pair of opposed support pads, where the pair of support pads are configured to (a) move toward a receptacle supported by the carriage as the carriage moves from the first location toward the second location, and (b) move away from a receptacle supported by the carriage as the carriage moves from the second location toward the first location. The carriage also includes a pair of meshed cam gears rotatably coupled to the first sidewall, where each cam gear is coupled to a different one of the support pads.

公开(公告)号：US10921338B2

公开(公告)日：2021-02-16

申请号：US16127939

申请日：2018-09-11

Applicant: Gen-Probe Incorporated

Inventor： Rolf Silbert ,  David Opalsky ,  David Aaron Buse ,  Robert J. Rosati ,  Olev Tammer ,  Richard Capella ,  Matthias Merten

IPC: G01N1/28 ,  G01N1/31 ,  G01N35/10 ,  G01N35/02 ,  G01N35/00 ,  G01F23/26 ,  G01N35/04 ,  C40B60/12

Abstract: A sample processing station includes two or more container holders on a platform that is rotatable about a central axis of rotation. Each holder is configured to rotate about a secondary axis of rotation. The station includes a capping/decapping mechanism to cap or decap a container held in one of the container holders and a drip tray movable between a first position not under the capping/decapping mechanism and a second position under the capping/decamping mechanism.

公开(公告)号：US12210028B2

公开(公告)日：2025-01-28

申请号：US17608745

申请日：2020-04-29

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  HongRan Peng ,  David Aaron Buse ,  David H. Combs

IPC: B65G47/90 ,  B01L3/00 ,  B01L9/06 ,  B65G43/08 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

Abstract: A receptacle delivery system includes a carriage configured to move from a first to a second location of an instrument. The carriage may be configured to removably support a receptacle and may include a receptacle clamping mechanism. The receptacle mechanism may be configured to apply a clamping force to the receptacle as the carriage moves from the first to the second location and release the clamping force as the carriage moves from the second to the first location.

公开(公告)号：US11614454B2

公开(公告)日：2023-03-28

申请号：US17129522

申请日：2020-12-21

Applicant: Gen-Probe Incorporated

Inventor： Rolf Silbert ,  David Opalsky ,  David Aaron Buse ,  Robert J. Rosati ,  Olev Tammer ,  Richard Capella ,  Matthias Merten

IPC: G01N1/28 ,  G01N1/31 ,  G01N35/10 ,  G01N35/02 ,  G01N35/00 ,  G01F23/263 ,  G01N35/04 ,  C40B60/12

Abstract: A sample processing station includes two or more container holders on a platform that is rotatable about a central axis of rotation. Each holder is configured to rotate about a secondary axis of rotation. The station includes a capping/decapping mechanism to cap or decap a container held in one of the container holders and an elevator with a chuck guide that contact the container holder as the chuck is lowered by the elevator to position the chuck with respect to the cap of the container held in the holder and to hold jaws of the container holder in a closed position. In embodiment, the chuck guide includes a yoke with opposed arms and spindles located near distal ends of the arms that engage beveled shoulders of the container holder.

公开(公告)号：US20180292427A1

公开(公告)日：2018-10-11

申请号：US16008731

申请日：2018-06-14

Applicant: Gen-Probe Incorporated

Inventor： Rolf Silbert ,  David Aaron Buse ,  Robert J. Rosati ,  Olev Tammer ,  Matthias Merten

IPC: G01N35/10 ,  G01F23/26 ,  G01N35/00 ,  G01N35/04 ,  C40B60/12

Abstract: A sample container of patient sample material includes a sample container barcode containing patient-identifying information. The sample container barcode on the sample container is read, and a tubular reaction vessel is provided to a printer module configured to print a barcode directly onto a surface of the tubular reaction vessel. The printer module prints a barcode on the surface of the reaction vessel by a thermal printing method, and the barcode printed onto the reaction vessel is associated with the sample container barcode.

公开(公告)号：USD907465S1

公开(公告)日：2021-01-12

申请号：US29682739

申请日：2019-03-07

Applicant: Gen-Probe Incorporated

Designer： David Aaron Buse

公开(公告)号：US10132821B2

公开(公告)日：2018-11-20

申请号：US15054943

申请日：2016-02-26

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  David Opalsky ,  David Aaron Buse ,  Robert J. Rosati ,  Olev Tammer ,  Richard Capella ,  Matthias Merten

IPC: G01N35/00 ,  G01N35/10 ,  G01F23/26 ,  G01N1/28 ,  C40B60/12 ,  G01N35/04

Abstract: The present invention provides a processing station for automatically processing a biological sample, a system for automated real-time inventory control of consumables within a biological sample handling or assay instrument, a high throughput random access automated instrument for processing biological samples, an automated instrument for processing or analysis of a sample, and processes for automated mucoid detection and elimination. Methods of using the disclosed instruments, mucoid detection processes, and systems to process and/or analyze samples are also disclosed.

公开(公告)号：US09604185B2

公开(公告)日：2017-03-28

申请号：US14211056

申请日：2014-03-14

Applicant: GEN-PROBE INCORPORATED

Inventor： David Aaron Buse ,  Byron J. Knight

IPC: B01F9/22 ,  B01F15/00 ,  B01F9/00 ,  B65D23/00 ,  B01F11/00 ,  B01L3/00 ,  G01N35/00

CPC classification number: B01F15/00837 ,  B01F9/0016 ,  B01F9/22 ,  B01F11/0014 ,  B01L3/523 ,  B01L2200/026 ,  B01L2200/142 ,  B65D23/00 ,  G01N2035/00524

Abstract: An apparatus configured for mixing the contents of one or more fluid containers includes a fluid container support platform configured to hold one or more fluid containers. The fluid container support platform is configured to index the container to one or more specified locations and to be moved in an orbital path about an orbital center independently of the rotation about the central axis of rotation. The apparatus further includes an indexing drive system configured to effect indexing movement of the container support platform and a vortex drive system configured to effect powered orbital movement of the container support platform about the orbital center. An evaporation limiting insert placed within containers reduces exposure of the fluid contents of the container to atmospheric air, thereby reducing susceptibility of the fluid contents to evaporation.

公开(公告)号：US12210031B2

公开(公告)日：2025-01-28

申请号：US18489478

申请日：2023-10-18

Applicant: GEN-PROBE INCORPORATED

Inventor： Rolf Silbert ,  HongRan Peng ,  David Aaron Buse ,  David H. Combs

IPC: G01N35/04 ,  B01L3/00 ,  B01L9/06 ,  B65G43/08 ,  B65G47/90 ,  G01N35/00 ,  G01N35/10

Abstract: A receptacle-supporting puck includes spring-biased fingers arranged about a vertical axis, each finger having a contact surface to contact a receptacle seated in the puck. A supporting disc of the puck includes a disc sidewall projecting from a base and defining a pocket for seating a receptacle, first cavities in the base extending toward the vertical axis, and a puck passageway extending through opposed portions of the disc sidewall transversely to and offset from the vertical axis. Each finger is rotatably coupled to the supporting disc at a corresponding first cavity. A synchronization disc is positioned in the pocket, and each of the fingers is coupled to the synchronization disc such that the contact surfaces of the fingers move synchronously toward and away from the vertical axis. A retaining ring couples the fingers, the supporting disc, and the synchronization disc together.

公开(公告)号：US12210030B2

公开(公告)日：2025-01-28

申请号：US18429318

申请日：2024-01-31

Applicant: Gen-Probe Incorporated

Inventor： Rolf Silbert ,  HongRan Peng ,  David Aaron Buse ,  David H. Combs

IPC: G01N35/04 ,  B01L3/00 ,  B01L9/06 ,  B65G43/08 ,  B65G47/90 ,  G01N35/00 ,  G01N35/10

Abstract: A method of delivering a receptacle to an instrument includes the steps of supporting a receptacle containing a fluid on a carrier, transporting the carrier supporting the receptacle on a conveyor extending adjacent to each of a plurality of instruments, transferring the receptacle from the carrier to a puck supported on a carriage when the carriage is positioned at a first location, moving the carriage with the receptacle seated in the puck from the first location to a second location within an instrument of the plurality of instruments, and drawing at least a portion of the fluid from the receptacle seated in the puck into a tip associated with a fluid extraction device of the instrument when the carriage is positioned at the second location.