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    Device and method for continuously producing emulsions or dispersions
    1.
    发明申请
    Device and method for continuously producing emulsions or dispersions 有权
    用于连续生产乳液或分散体的装置和方法

    公开(公告)号：US20070025177A1

    公开(公告)日：2007-02-01

    申请号：US10549700

    申请日：2003-03-21

    Applicant: Gerd Dahms ,  Helmut Hegmann

    Inventor： Gerd Dahms ,  Helmut Hegmann

    IPC: B01F11/00

    CPC classification number: B01F3/0807 ,  B01F3/0853 ,  B01F3/1221 ,  B01F7/00908 ,  B01F13/1013 ,  B01F13/1016 ,  B01F15/00207

    Abstract: A device for continuously producing emulsions or dispersions while excluding air comprises a mixing vessel, which is closed on all sides and which has supply tubes and discharge tubes for introducing and discharging fluid substances or compositions, and also an impeller, which permits an agitating input into the emulsion or dispersion without generating cavitation forces and without high-pressure homogenization. For preparing the cosmetic emulsions of the invention, as well, emulsifiers are generally used.

    Abstract translation: 用于在排除空气的同时连续生产乳液或分散体的装置包括混合容器，其在所有侧面都是封闭的，并且具有用于引入和排出流体物质或组合物的供应管和排放管，以及允许搅拌输入 乳液或分散体，而不会产生气蚀力而不产生高压均质。 为了制备本发明的化妆品乳液，通常也使用乳化剂。

    Mssn dispersion and method for producing the same
    2.
    发明申请
    Mssn dispersion and method for producing the same 审中-公开
    Mssn分散体及其制造方法

    公开(公告)号：US20060257334A1

    公开(公告)日：2006-11-16

    申请号：US10550193

    申请日：2004-02-19

    Applicant: Gerd Dahms ,  Holger Seidel

    Inventor： Gerd Dahms ,  Holger Seidel

    IPC: A61K8/18

    CPC classification number: A61K9/5123 ,  A61K9/5146

    Abstract: Membrane-structured solid nanoparticles having an average diameter in the range from 10 to 10 000 nm which are solid at 25° C. and have a combination of active compound vehicle particles and emulsifiers such as to form membranes which infiltrate the entire nanoparticles so that there are emulsifiers in the interior and on the surface of the nanoparticles are described. An aqueous vehicle dispersion in which there are solid active compound vehicle particles which are based on wax, polymer or lipid, have an average diameter in the range from 10 to 10 000 nm, and comprise at least one active pharmaceutical, cosmetic and/or food technology compound is produced by a) mixing the active compound with the wax-, polymer- or lipid-based active compound vehicle and at least one emulsifier which leads in stage b) to the formation of a lyotropic liquid-crystalline mixed phase, at a temperature above the melting or softening point of the active compound vehicle, to form a phase B, b) mechanically mixing the phase B with an aqueous phase A, which may comprise an emulsifier, at a temperature above the melting or softening point of the active compound vehicle, the weight ratio of phase B to phase A being 1:5 to 5:1, without high-pressure homogenization, to form a lyotropic liquid-crystalline mixed phase, c) diluting the mixed phase with an aqueous phase, which may comprise an emulsifier, at an aqueous-phase temperature which is below the melting or softening point of the active compound vehicle, with stirring and without high-pressure homogenization, to a desired final concentration of the dispersion.

    Abstract translation: 平均直径在10〜10000nm的膜结构固体纳米颗粒，其在25℃下是固体，并且具有活性化合物载体颗粒和乳化剂的组合，以形成渗透整个纳米颗粒的膜，使得在 是在纳米颗粒的内部和表面上的乳化剂。 其中存在基于蜡，聚合物或脂质的固体活性化合物载体颗粒的水性载体分散体，其平均直径在10至10000纳米的范围内，并且包含至少一种活性药物，化妆品和/或食物 通过以下方式制备技术化合物：a）将活性化合物与基于蜡，聚合物或脂质的活性化合物载体和至少一种在阶段b）中导致的乳化剂混合以形成溶致液晶混合相， 温度高于活性化合物载体的熔点或软化点，以形成B相，b）在高于活性成分的熔点或软化点的温度下，将B相与可能包含乳化剂的水相A机械混合 复合载体，B相至A相的重量比为1：5至5：1，无需高压均质，形成溶致液晶混合相，c）用水相稀释混合相， 公司 在搅拌和无高压均质化下，在低于活性化合物载体的熔点或软化点的水相温度下，使乳化剂达到期望的最终浓度的分散体。

    Composition and method employing membrane structured solid nanoparticles for enhanced delivery of oral care actives
    3.
    发明申请
    Composition and method employing membrane structured solid nanoparticles for enhanced delivery of oral care actives 审中-公开
    使用膜结构固体纳米颗粒增强口服护理活性物质的组合物和方法

    公开(公告)号：US20060024248A1

    公开(公告)日：2006-02-02

    申请号：US11232006

    申请日：2005-09-22

    Applicant: Eric Spengler ,  Gerd Dahms

    Inventor： Eric Spengler ,  Gerd Dahms

    IPC: A61K8/18

    CPC classification number: A61Q11/00 ,  A61K8/31 ,  A61K8/37 ,  A61K8/922 ,  A61K8/927 ,  A61K2800/413 ,  B82Y5/00

    Abstract: An oral care composition containing membrane-structured solid nanoparticles formed from a lyotropic liquid-crystalline mixed phase having an average particle diameter in the range of 10 to 1,000 nm. The nanoparticles are generally solid at 25° C. and are a combination of agent-carrier particles and emulsifiers. The membranes penetrate the nanoparticles so that the emulsifiers are present in the interior and on the surface of the nanoparticles.

    Abstract translation: 一种口腔护理组合物，其含有平均粒径在10〜1000nm范围内的溶致液晶混合相形成的膜结构固体纳米颗粒。 纳米颗粒在25℃下通常是固体，并且是试剂载体颗粒和乳化剂的组合。 膜渗透纳米颗粒，使得乳化剂存在于纳米颗粒的内部和表面。

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