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1.发明授权Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway 有权用于从类异戊二烯途径生产化学和药物产品的微生物工程公开(公告)号：US08927241B2
公开(公告)日：2015-01-06
申请号：US13249388
申请日：2011-09-30
Applicant: Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
Inventor： Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
CPC classification number: C12P5/007 , C12N15/70 , C12P7/42 , C12P9/00 , C12P15/00 , C12P17/02 , C12P19/56 , C12P23/00 , C12Q1/689 , C12Q2600/158
Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
Abstract translation: 本发明涉及通过微生物工程生产一种或多种萜类化合物，涉及包含萜类化合物的产品的制造。
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公开(公告)号：US20120315672A1
公开(公告)日：2012-12-13
申请号：US13509032
申请日：2010-11-10
Applicant: Effendi Leonard , Parayil K. Ajikumar , Kristala Lanett Jones Prather , Gregory Stephanopoulos , Kelly Thayer
Inventor： Effendi Leonard , Parayil K. Ajikumar , Kristala Lanett Jones Prather , Gregory Stephanopoulos , Kelly Thayer
CPC classification number: C12N9/88 , C12N9/1085 , C12P15/00 , C12Y205/01029
Abstract: The invention relates to recombinant expression of terpenoid synthase enzymes and geranylgeranyl diphosphate synthase (GGPPS) enzymes in cells and the production of diterpenoids.
Abstract translation: 本发明涉及细胞中萜类合酶和香叶基香叶基二磷酸合成酶（GGPPS）酶的重组表达和二萜类化合物的生成。
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3.发明授权公开(公告)号：US09284570B2
公开(公告)日：2016-03-15
申请号：US13306633
申请日：2011-11-29
Applicant: Gregory Stephanopoulos , Parayil K. Ajikumar
Inventor： Gregory Stephanopoulos , Parayil K. Ajikumar
IPC: C12P15/00 , C12N9/90 , C12N9/88 , C12N9/10 , C12N9/02 , C12N9/12 , C12N15/00 , C12N1/20 , C07H21/04 , C12N15/82 , C12N15/70 , A01H5/00 , A01H13/00 , A23L1/236 , A23L2/60 , C12P7/42 , C12P17/02
CPC classification number: C12N15/8243 , A01H5/00 , A01H13/00 , A23L2/60 , A23L27/36 , C12N9/0042 , C12N9/0073 , C12N9/0085 , C12N9/1085 , C12N9/1288 , C12N9/88 , C12N9/90 , C12N15/70 , C12P7/42 , C12P15/00 , C12P17/02 , C12Y106/02004 , C12Y114/13 , C12Y114/13076 , C12Y114/13078 , C12Y114/99009 , C12Y205/01029 , C12Y402/03019 , C12Y505/01012 , C12Y505/01013 , Y02P20/52
Abstract: The invention relates to recombinant expression of a steviol or steviol glycosides biosynthetic pathway enzymes in cells and the production of steviol or steviol glycosides.
Abstract translation: 本发明涉及细胞中甜菊醇或甜菊糖苷苷合成途径酶的重组表达，以及甜菊醇或甜菊糖苷的生产。
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Patent Agency Ranking
4.发明授权Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway 有权用于从类异戊二烯途径生产化学和药物产品的微生物工程公开(公告)号：US08512988B2
公开(公告)日：2013-08-20
申请号：US12943477
申请日：2010-11-10
Applicant: Parayil K. Ajikumar , Gregory Stephanopoulos , Heng Phon Too
Inventor： Parayil K. Ajikumar , Gregory Stephanopoulos , Heng Phon Too
Abstract: The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.
Abstract translation: 本发明涉及一种紫杉二烯合酶和一种香叶基香叶基二磷酸合成酶（GGPPS）在细胞中的表达和萜类化合物的产生。
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5.发明申请MICROBIAL PRODUCTION OF NATURAL SWEETENERS, DITERPENOID STEVIOL GLYCOSIDES 有权微生物生产天然维生素DITERPENOID STEVIOL GLYCOSIDES公开(公告)号：US20120164678A1
公开(公告)日：2012-06-28
申请号：US13306633
申请日：2011-11-29
Applicant: Gregory Stephanopoulos , Parayil K. Ajikumar
Inventor： Gregory Stephanopoulos , Parayil K. Ajikumar
CPC classification number: C12N15/8243 , A01H5/00 , A01H13/00 , A23L2/60 , A23L27/36 , C12N9/0042 , C12N9/0073 , C12N9/0085 , C12N9/1085 , C12N9/1288 , C12N9/88 , C12N9/90 , C12N15/70 , C12P7/42 , C12P15/00 , C12P17/02 , C12Y106/02004 , C12Y114/13 , C12Y114/13076 , C12Y114/13078 , C12Y114/99009 , C12Y205/01029 , C12Y402/03019 , C12Y505/01012 , C12Y505/01013 , Y02P20/52
Abstract: The invention relates to recombinant expression of a steviol or steviol glycosides biosynthetic pathway enzymes in cells and the production of steviol or steviol glycosides.
Abstract translation: 本发明涉及细胞中甜菊醇或甜菊糖苷苷合成途径酶的重组表达，以及甜菊醇或甜菊糖苷的生产。
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公开(公告)号：US08062878B2
公开(公告)日：2011-11-22
申请号：US12615985
申请日：2009-11-10
Applicant: Effendi Leonard , Parayil K. Ajikumar , Kristala Lanett Jones Prather , Gregory Stephanopoulos , Kelly Thayer
Inventor： Effendi Leonard , Parayil K. Ajikumar , Kristala Lanett Jones Prather , Gregory Stephanopoulos , Kelly Thayer
CPC classification number: C12N9/88 , C12N9/1085 , C12P15/00 , C12Y205/01029
Abstract: The invention relates to recombinant expression of terpenoid synthase enzymes and geranylgeranyl diphosphate synthase (GGPPS) enzymes in cells and the production of diterpenoids.
Abstract translation: 本发明涉及细胞中萜类合酶和香叶基香叶基二磷酸合成酶（GGPPS）酶的重组表达和二萜类化合物的生成。
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7.发明申请公开(公告)号：US20120107893A1
公开(公告)日：2012-05-03
申请号：US13249388
申请日：2011-09-30
Applicant: Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
Inventor： Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
IPC: C12P5/00
CPC classification number: C12P5/007 , C12N15/70 , C12P7/42 , C12P9/00 , C12P15/00 , C12P17/02 , C12P19/56 , C12P23/00 , C12Q1/689 , C12Q2600/158
Abstract: The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
Abstract translation: 本发明涉及通过微生物工程生产一种或多种萜类化合物，涉及包含萜类化合物的产品的制造。
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8.发明申请公开(公告)号：US20110189717A1
公开(公告)日：2011-08-04
申请号：US12943477
申请日：2010-11-10
Applicant: Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
Inventor： Parayil K. Ajikumar , Gregory Stephanopoulos , Too Heng Phon
Abstract: The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.
Abstract translation: 本发明涉及一种紫杉二烯合酶和一种香叶基香叶基二磷酸合成酶（GGPPS）在细胞中的表达和萜类化合物的产生。
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