公开(公告)号：US3910995A

公开(公告)日：1975-10-07

申请号：US39568173

申请日：1973-09-10

Applicant: HOOKER CHEMICALS PLASTICS CORP

Inventor： GELFAND SAMUEL

IPC: C07C205/58 ,  C07C79/46

CPC classification number: C07C205/58 ,  C07C201/08

Abstract: A novel process for the preparation of 2,5-dihalo-3-nitrobenzoic acid and derivatives thereof is provided. The process comprises treating a compound of the formula

WHEREIN X and Y are halogen, and Z is selected from the group consisting of halogen and anhydride, namely 2,5-dihalobenzoyloxywithout an intermediate hydrolysis step, with a sulfur-containing compound selected from the group of sulfur trioxide, oleum, chloro-sulfonic acid and mixtures thereof and a nitrating agent to produce 2,5-dihalo-3-nitrobenzoic acid. The process gives an increased yield of the desired 3-nitro- isomer product thereby decreasing the amount of undesired by-product isomers.

Abstract translation: 提供了一种制备2,5-二卤代-3-硝基 - 苯甲酸及其衍生物的新方法。 该方法包括处理式WHEREIN X和Y为卤素的化合物，Z选自卤素和酸酐，即不含中间水解步骤的2,5-二卤代苯甲酰氧基，其中含硫化合物选自 三氧化硫，发烟硫酸，氯磺酸及其混合物的组和硝化剂以产生2,5-二卤代-3-硝基苯甲酸。 该方法产生所需3-硝基异构体产物的产率增加，从而减少不需要的副产物异构体的量。

公开(公告)号：US3869510A

公开(公告)日：1975-03-04

申请号：US36420073

申请日：1973-05-25

Applicant: HOOKER CHEMICALS PLASTICS CORP

Inventor： GELFAND SAMUEL ,  GRAHAM JOHN C

IPC: C07C63/70 ,  B01J27/00 ,  C07B61/00 ,  C07C51/00 ,  C07C51/58 ,  C07C51/62 ,  C07C67/00 ,  C07C63/10

CPC classification number: C07C51/58 ,  C07C51/62 ,  C07C51/64 ,  C07C63/70

Abstract: An improved process is disclosed for the preparation of 3,5dichlorobenzoyl chloride which comprises decarbonylating 5chloroisophthaloyl chloride in the presence of a catalytic amount of a compound selected from the group consisting of palladium chloride, palladium/barium sulfate, palladium/aluminum oxide and mixtures thereof, at a temperature of not less than about 245 degrees centigrade.

Abstract translation: 公开了用于制备3,5-二氯苯甲酰氯的改进方法，其包括在催化量的选自氯化钯，钯/硫酸钡，钯/氧化铝的化合物存在下，使5-氯间苯二甲酰氯脱碳化 及其混合物，温度不低于约245摄氏度。