公开(公告)号：US20220227780A1

公开(公告)日：2022-07-21

申请号：US16648865

申请日：2018-09-25

Applicant: IDEAYA BIOSCIENCES, INC.

Inventor： Hilary Plake BECK ,  Leah Brigit CLEARY ,  Michael Patrick DILLON ,  Marcos GONZALES-LOPEZ ,  Luis Ruben P. MARTINEZ ,  James Clifford SUTTON

IPC: C07D495/04 ,  A61K31/4365 ,  C07D519/00 ,  A61K31/437 ,  A61K31/5025 ,  A61K31/519 ,  A61P35/00

Abstract: Compounds are provided having Formula (I): wherein R, R1, Cyc and A have the meanings provided herein. The compounds have utility in the treatment of diseases, either alone or in combination with other agents.