公开(公告)号：US20210238667A1

公开(公告)日：2021-08-05

申请号：US16973415

申请日：2019-06-07

Applicant: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

Inventor： Pantelis GEORGIOU ,  Ling-Shan YU ,  Kenny Malpartida CARDENAS ,  Matthew C. FISHER ,  Jesus Rodriguez MANZANO ,  Nicolas MOSER

IPC: C12Q1/6858 ,  C12Q1/6876

Abstract: The present application relates to methods for detecting a first allele of a single nucleotide polymorphism (SNP) in a nucleic acid sequence under isothermal conditions using primers specific for said first allele, in particular using Loop mediated isothermal amplification (LAMP), wherein the amplification of a second allele is prevented by using blocking primers.

公开(公告)号：US20210172030A1

公开(公告)日：2021-06-10

申请号：US16973414

申请日：2019-06-07

Applicant: IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

Inventor： Pantelis GEORGIOU ,  Ling-Shan YU ,  Kenny Malpartida CARDENAS ,  Matthew C. FISHER ,  Jesus Rodriguez MANZANO ,  Nicolas MOSER

IPC: C12Q1/6895 ,  C12Q1/6858

Abstract: The present application relates to methods for detecting a tandem repeat in a nucleic acid sequence under isothermal conditions using primers.