公开(公告)号：US20180126373A1

公开(公告)日：2018-05-10

申请号：US15680736

申请日：2017-08-18

Applicant: INVIDX CORP.

Inventor： James SAMSOONDAR

IPC: B01L3/00 ,  G01N33/86

CPC classification number: B01L3/502 ,  B01L2200/025 ,  B01L2200/0605 ,  B01L2200/0684 ,  B01L2300/042 ,  B01L2300/043 ,  B01L2300/046 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0487 ,  B01L2400/0688 ,  G01N33/86

Abstract: A disposable cartridge for rapidly metering a sample for measuring a property of the sample is described. The cartridge can receive a sample when it is in an unsealed configuration, and a cap is used to facilitate metering of the sample and sealing the cartridge. When the cartridge is in a sealed configuration, pressurised air is used to push the metered sample into a chamber containing at least one reagent, and subsequently into a detection chamber for measuring a property of the sample.

公开(公告)号：US20210088534A1

公开(公告)日：2021-03-25

申请号：US16575645

申请日：2019-09-19

Applicant: INVIDX CORP.

Inventor： James SAMSOONDAR

IPC: G01N33/80 ,  G01N33/569 ,  G01N33/49 ,  G01N33/555

Abstract: A joint point-of-care testing (POCT) analyzer, and a system comprising an analyzer and a cartridge, for measuring one or more analyte quantities per unit volume of blood and one or more formed element quantities per unit volume of blood, is described. Examples of formed elements of blood are red blood cells and white blood cells, and cell counts are determined by imaging using a two-dimensional multi-channel detector. Examples of analytes are hemoglobin and bilirubin, and hemoglobin and bilirubin concentrations are determined by spectroscopy using a one-dimensional multi-channel detector. Other examples of analytes are electrolytes, and electrolyte concentrations may be determined using biosensors incorporated in the cartridges.

公开(公告)号：US20210086173A1

公开(公告)日：2021-03-25

申请号：US16854201

申请日：2020-04-21

Applicant: INVIDX CORP.

Inventor： James SAMSOONDAR

IPC: B01L3/00 ,  G01N35/00

Abstract: A joint point-of-care testing (POCT) analyzer, and a system comprising an analyzer and a cartridge, for measuring one or more analyte quantities per unit volume of blood and one or more formed element quantities per unit volume of blood, is described. Examples of formed elements of blood are red blood cells and white blood cells, and cell counts are determined by imaging using a two-dimensional multi-channel detector. Examples of analytes are hemoglobin and bilirubin, and hemoglobin and bilirubin concentrations are determined by spectroscopy using a one-dimensional multi-channel detector. Other examples of analytes are electrolytes, and electrolyte concentrations may be determined using biosensors incorporated in the cartridges.

公开(公告)号：US20220091148A1

公开(公告)日：2022-03-24

申请号：US17394672

申请日：2021-08-05

Applicant: INVIDX CORP.

Inventor： James SAMSOONDAR

IPC: G01N35/10 ,  B01L3/00 ,  G01N21/03 ,  G01N21/25 ,  G01N27/416 ,  G01N33/49

Abstract: A point-of-care testing (POCT) system comprising an analyzer, a measurement cartridge, and a calibration cartridge for calibrating the measurement cartridge is described. The measurement cartridge comprises at least one electrochemical sensor for measuring the one or more properties of the blood sample, and the calibration cartridge comprises a similar at least one electrochemical sensor and at least one sealed blister containing calibration fluid for calibrating the measurement cartridge. Examples of properties of the blood sample may be pH, blood gases, electrolytes, and metabolites like glucose and creatinine. The measurement cartridge may also comprise an optical chamber for measuring for example, bilirubin and hemoglobin species, for which the analyzer comprises stored calibration algorithms. The optical chamber may be disposed in any location in the measurement cartridge, for receiving a portion of the blood sample.

公开(公告)号：US20190224667A1

公开(公告)日：2019-07-25

申请号：US16296539

申请日：2019-03-08

Applicant: INVIDX CORP.

Inventor： James SAMSOONDAR

IPC: B01L3/00 ,  G01N33/49

Abstract: Disposable cartridges comprising hinged caps and optical chambers for measuring one or more properties of a blood sample are described. Blood flow in the disposable cartridges may be regulated by either positive or negative pressure. Other embodiments of cartridges comprising a biosensor chamber disposed downstream of the optical chamber are also described. Methods for measuring one or more properties of a blood sample using different cartridge embodiments are provided.