公开(公告)号：US20250057913A1

公开(公告)日：2025-02-20

申请号：US18721923

申请日：2022-12-22

Applicant: ITALFARMACO SPA

Inventor： Daniela MODENA ,  Giovanni SANDRONE ,  Andrea STEVENAZZI ,  Christian STEINKÜHLER ,  Natalia S. PELLEGATA ,  Stefan SCHULZ

IPC: A61K38/12 ,  A61K45/06 ,  A61P35/00

Abstract: The present invention relates to the use of the compound of formula (I) or the pharmaceutically acceptable salts and/or solvates thereof in the treatment of SSTR3 expressing tumors, selected from non-functioning pituitary adenomas (NFPAs) or other neuroendocrine-related malignancies, selected from pancreatic tumors, pheochromocytomas, paragangliomas, lung carcinoids or breast cancer. More specifically, the present invention provides to the use of pharmaceutical compositions comprising the compound of formula (I) or the pharmaceutically acceptable salts and/or solvates thereof and at least one physiologically acceptable excipient in the treatment of a patient affected by SSTR3 expressing tumors, selected from non-functioning pituitary adenomas (NFPAs) or other neuroendocrine-related malignancies, selected from pancreatic tumors, pheochromocytomas, paragangliomas, lung carcinoids or breast cancer.