公开(公告)号：US20180037862A1

公开(公告)日：2018-02-08

申请号：US15550537

申请日：2016-03-16

Applicant: Iogen Corporation

Inventor： Brian Foody ,  Jeffrey S. Tolan ,  Daniel MacDonald ,  Patrick J. Foody

IPC: C12M1/00 ,  C12P7/14 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12M45/03 ,  B01D53/002 ,  B01D2257/302 ,  C12M45/09 ,  C12M45/20 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12Y302/01004 ,  D21C1/02 ,  D21C1/04 ,  D21C3/06 ,  Y02E50/16

Abstract: The present invention provides a process for producing a fermentation product from a lignocellulosic feedstock. The process comprises soaking a lignocellulosic feedstock in an aqueous solution to produce a soaked feedstock. The soaked feedstock is at least partially dewatered and the at least partially dewatered feedstock is subjected to pretreating in the presence of sulfur dioxide, sulfurous acid or a combination thereof to produce a pretreated feedstock composition. The pretreated feedstock composition is fed to an enzymatic hydrolysis in which the concentration of dissolved solids fed to the enzymatic hydrolysis is at least 50% (w/w) of the concentration of dissolved solids in the pretreated feedstock composition. The cellulose in the pretreated feedstock composition is hydrolyzed with cellulase enzymes in the presence of the dissolved solids to produce glucose. The glucose is fermented to produce the fermentation product.

公开(公告)号：US09574212B2

公开(公告)日：2017-02-21

申请号：US15199638

申请日：2016-06-30

Applicant: Iogen Corporation

Inventor： Brian Foody ,  Jeffrey S. Tolan ,  Daniel MacDonald ,  Patrick J. Foody

IPC: C12P7/14 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  C12M1/00 ,  D21C1/02 ,  D21C1/04 ,  B01D53/00

CPC classification number: C12M45/03 ,  B01D53/002 ,  B01D2257/302 ,  C12M45/09 ,  C12M45/20 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12Y302/01004 ,  D21C1/02 ,  D21C1/04 ,  D21C3/06 ,  Y02E50/16

Abstract: The disclosure provides a process for producing a fermentation product from a lignocellulosic feedstock. The process describes soaking a lignocellulosic feedstock in an aqueous solution to produce a soaked feedstock. The soaked feedstock is at least partially dewatered and the at least partially dewatered feedstock is subjected to pretreating in the presence of sulfur dioxide, sulfurous acid or a combination thereof to produce a pretreated feedstock composition. The pretreated feedstock composition is fed to an enzymatic hydrolysis in which the concentration of dissolved solids fed to the enzymatic hydrolysis is at least 50% (w/w) of the concentration of dissolved solids in the pretreated feedstock composition. The cellulose in the pretreated feedstock composition is hydrolyzed with cellulase enzymes in the presence of the dissolved solids to produce glucose. The glucose is fermented to produce the fermentation product.

Abstract translation: 本公开提供了从木质纤维素原料生产发酵产物的方法。 该方法描述了将木质纤维素原料浸泡在水溶液中以产生浸渍的原料。 浸渍的原料至少部分脱水，并且在二氧化硫，亚硫酸或其组合的存在下对至少部分脱水的原料进行预处理以产生预处理的原料组合物。 将预处理的原料组合物加入酶水解，其中进料到酶水解的溶解固体的浓度为预处理的原料组合物中溶解固体浓度的至少50％（w / w）。 预处理的原料组合物中的纤维素在溶解的固体存在下用纤维素酶水解以产生葡萄糖。 葡萄糖被发酵以产生发酵产物。

公开(公告)号：US20160312249A1

公开(公告)日：2016-10-27

申请号：US15199638

申请日：2016-06-30

Applicant: Iogen Corporation

Inventor： Brian Foody ,  Jeffrey S. Tolan ,  Daniel MacDonald ,  Patrick J. Foody

IPC: C12P7/14 ,  C12M1/00

CPC classification number: C12M45/03 ,  B01D53/002 ,  B01D2257/302 ,  C12M45/09 ,  C12M45/20 ,  C12P7/10 ,  C12P7/14 ,  C12P19/02 ,  C12P19/14 ,  C12P2201/00 ,  C12Y302/01004 ,  D21C1/02 ,  D21C1/04 ,  D21C3/06 ,  Y02E50/16

Abstract: The present invention provides a process for producing a fermentation product from a lignocellulosic feedstock. The process comprises soaking a lignocellulosic feedstock in an aqueous solution to produce a soaked feedstock. The soaked feedstock is at least partially dewatered and the at least partially dewatered feedstock is subjected to pretreating in the presence of sulfur dioxide, sulfurous acid or a combination thereof to produce a pretreated feedstock composition. The pretreated feedstock composition is fed to an enzymatic hydrolysis in which the concentration of dissolved solids fed to the enzymatic hydrolysis is at least 50% (w/w) of the concentration of dissolved solids in the pretreated feedstock composition. The cellulose in the pretreated feedstock composition is hydrolyzed with cellulase enzymes in the presence of the dissolved solids to produce glucose. The glucose is fermented to produce the fermentation product.

Abstract translation: 本发明提供从木质纤维素原料生产发酵产物的方法。 该方法包括将木质纤维素原料浸泡在水溶液中以产生浸泡的原料。 浸渍的原料至少部分脱水，并且在二氧化硫，亚硫酸或其组合的存在下对至少部分脱水的原料进行预处理以产生预处理的原料组合物。 将预处理的原料组合物加入酶水解，其中进料到酶水解的溶解固体的浓度为预处理的原料组合物中溶解固体浓度的至少50％（w / w）。 预处理的原料组合物中的纤维素在溶解的固体存在下用纤维素酶水解以产生葡萄糖。 葡萄糖被发酵以产生发酵产物。