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    Touch input device having digital ambient light sampling
    1.
    发明授权
    Touch input device having digital ambient light sampling 失效
    具有数字环境光采样的触摸式输入设备

    公开(公告)号：US4943806A

    公开(公告)日：1990-07-24

    申请号：US394261

    申请日：1988-12-06

    Applicant: Timothy E. Masters ,  Paul B. Lucas ,  James E. Garrett ,  John K. Carstedt

    Inventor： Timothy E. Masters ,  Paul B. Lucas ,  James E. Garrett ,  John K. Carstedt

    IPC: G06F3/033 ,  G06F3/042

    CPC classification number: G06F3/0421

    Abstract: A touch input device which continuously samples and digitally stores ambient light readings and compares these with previously stored readings is taught. Briefly stated, a phototransistor is turned on before, during and after an LED emitter energization. An ambient value is calculated which is subtracted from the value obtained during LED firing so as to develop a signal indicative of the presence or absence of the LED pulse, irrespective of ambient light fluctuations. The ambient level is stored for comparison purposes during the next sampling of the associated phototransistor.

    Abstract translation: 教导了连续采样和数字存储环境光读数并将其与先前存储的读数进行比较的触摸输入装置。 简而言之，在LED发射极通电之前，期间和之后，光电晶体管导通。 计算环境值，其从在LED点火期间获得的值中减去，以便产生指示LED脉冲的存在或不存在的信号，而不管环境光波动。 在相关光电晶体管的下一次采样期间，存储环境电平用于比较目的。

    Methods and systems for altering the speaker orientation of a portable system
    2.
    发明授权
    Methods and systems for altering the speaker orientation of a portable system 有权
    用于改变便携式系统的扬声器方向的方法和系统

    公开(公告)号：US08600084B1

    公开(公告)日：2013-12-03

    申请号：US10984334

    申请日：2004-11-09

    Applicant: James E. Garrett

    Inventor： James E. Garrett

    IPC: H04R5/02 ,  H04R1/02 ,  H02B1/00

    CPC classification number: H04R5/04 ,  H04R2499/15

    Abstract: Computer-implemented methods are provided. One method includes determining an orientation of a display of a portable system. The method also includes altering an orientation of two speakers arranged along one side of the system based on the orientation of the display. Another method includes determining an orientation of a display of a portable system and determining an orientation of two speakers of the system based on the orientation of the display. If a current orientation of the two speakers differs from the determined orientation of the two speakers, the method includes altering the current orientation of the speakers such that they have the determined orientation. A portable system is also provided that includes means for determining an orientation of a display of the system. The system also includes means for altering an orientation of two speakers arranged along one side of the system based on the orientation of the display.

    Abstract translation: 提供了计算机实现的方法。 一种方法包括确定便携式系统的显示器的方向。 该方法还包括基于显示器的取向改变沿着系统的一侧布置的两个扬声器的取向。 另一种方法包括确定便携式系统的显示器的方向，并且基于显示器的取向来确定系统的两个扬声器的取向。 如果两个扬声器的当前定向方向与确定的两个扬声器方位不同，则该方法包括改变扬声器的当前方向以使其具有确定的方位。 还提供了一种便携式系统，其包括用于确定系统的显示器的方位的装置。 该系统还包括用于基于显示器的取向来改变沿着系统的一侧布置的两个扬声器的取向的装置。

    β-Superfamily conotoxins
    3.
    发明授权
    β-Superfamily conotoxins 有权
    β-超家族芋螺毒素

    公开(公告)号：US07115708B2

    公开(公告)日：2006-10-03

    申请号：US11198847

    申请日：2005-08-08

    Applicant: Robert M. Jones ,  Baldomero M. Olivera ,  Maren Watkins ,  James E. Garrett

    Inventor： Robert M. Jones ,  Baldomero M. Olivera ,  Maren Watkins ,  James E. Garrett

    IPC: C07K4/12 ,  A61K51/08

    CPC classification number: C07K14/43504

    Abstract: The present invention is directed to β-superfamily conotoxin peptides, derivatives or pharmaceutically acceptable salts thereof. The present invention is further directed to the use of this peptide, derivatives thereof and pharmaceutically acceptable salts thereof for the treatment of disorders associated with voltage-gated ion channels, ligand gated channels and other receptors. The invention is further directed to nucleic acid sequences encoding the β-superfamily conotoxin peptides and encoding β-superfamily conotoxin propeptides, as well as the β-superfamily conotoxin propeptides.

    Abstract translation: 本发明涉及β-超家族荚果毒素肽，其衍生物或药学上可接受的盐。 本发明进一步涉及该肽，其衍生物和其药学上可接受的盐在治疗与电压门控离子通道，配体门控通道和其它受体相关的病症中的用途。 本发明还涉及编码β-超家族荚果毒素肽和编码β-超家族荚果毒素前肽以及β-超家族荚果毒素前肽的核酸序列。

    G-protein fusion receptors and constructs encoding same
    6.
    发明授权
    G-protein fusion receptors and constructs encoding same 失效
    G蛋白融合受体和编码相同的构建体

    公开(公告)号：US07262280B1

    公开(公告)日：2007-08-28

    申请号：US09679664

    申请日：2000-10-03

    Applicant: Thomas M. Stormann ,  Lance G. Hammerland ,  Laura L. Storjohann ,  James G. Busby ,  James E. Garrett ,  Rachel T. Simin

    Inventor： Thomas M. Stormann ,  Lance G. Hammerland ,  Laura L. Storjohann ,  James G. Busby ,  James E. Garrett ,  Rachel T. Simin

    IPC: C07K1/00 ,  C08H1/00 ,  C07H21/04 ,  C12P21/06 ,  C12N1/20

    CPC classification number: C07K14/723 ,  C08H1/00

    Abstract: The present invention features G-protein fusion receptors and chimeric GABAB receptors (GABABRs), nucleic acid encoding such receptors, and the use of such receptors and nucleic acid. G-protein fusion receptors comprise at least one domain from a CaR, an mGluR, and/or a GABAB receptor fused directly or through a linker to a guanine nucleotide-binding protein (G-protein). Chimeric GABABRs comprise at least one of a GABABR extracellular domain, a GABABR transmembrane domain, or a GABABR intracellular domain and one or more domains from a mGluR subtype 8 (mGluR8) and/or a CaR.

    Abstract translation: 本发明的特征在于G蛋白融合受体和嵌合GABA B受体（GABA B R Rs），编码这些受体的核酸，以及这些受体和核酸的用途。 G-蛋白融合受体包含至少一个直接或通过接头与鸟嘌呤核苷酸结合蛋白（G-蛋白）融合的CaR，mGluR和/或GABA B B受体的结构域。 嵌合的GABA B R Rs包含GABA B R R胞外域，GABA B R R跨膜结构域或GABA B跨膜结构域中的至少一种， B细胞内结构域和来自mGluR亚型8（mGluR8）和/或CaR的一个或多个结构域。

    System and method for identifying expansion devices in a computer system
    7.
    发明授权
    System and method for identifying expansion devices in a computer system 失效
    用于识别计算机系统中的扩展设备的系统和方法

    公开(公告)号：US5594873A

    公开(公告)日：1997-01-14

    申请号：US353047

    申请日：1994-12-08

    Applicant: James E. Garrett

    Inventor： James E. Garrett

    IPC: G06F9/445 ,  H01J13/00

    CPC classification number: G06F9/4411

    Abstract: A method and apparatus for identifying option modules or expansion devices coupled to an expansion bus using time domain methods. According to the present invention, each expansion device includes logic circuitry that asserts an identification signal a preset time duration after a host reset signal is pulsed. A unique preset time duration or time constant is designated for each expansion device, and the host computer identifies each expansion device by the length or duration of the identification signal. In the preferred embodiment, during the power-on sequence the computer system asserts a reset signal pulse to the identification logic in each respective expansion device which directs the expansion device to assert its identifying signal. The host computer determines the length of time between assertion of the reset signal pulse and assertion of the identification signal and uses this information to determine the type of expansion device.

    Abstract translation: 一种用于识别使用时域方法耦合到扩展总线的选项模块或扩展设备的方法和装置。 根据本发明，每个扩展装置包括逻辑电路，其在主机复位信号被脉冲之后断言识别信号预设的持续时间。 为每个扩展设备指定唯一的预设持续时间或时间常数，并且主计算机根据识别信号的长度或持续时间来识别每个扩展设备。 在优选实施例中，在上电序列期间，计算机系统向每个相应的扩展装置中的识别逻辑断言复位信号脉冲，其指导扩展装置断言其识别信号。 主计算机确定重置信号脉冲的断言和识别信号的断言之间的时间长度，并使用该信息来确定扩展设备的类型。

    Touch input device
    8.
    发明授权
    Touch input device 失效
    触摸输入设备

    公开(公告)号：US4761637A

    公开(公告)日：1988-08-02

    申请号：US928652

    申请日：1986-11-05

    Applicant: Paul B. Lucas ,  James E. Garrett

    Inventor： Paul B. Lucas ,  James E. Garrett

    IPC: G06F3/033 ,  G06F3/042 ,  G08C9/00 ,  G08C21/00

    CPC classification number: G06F3/0421

    Abstract: An infrared touch input system is taught. Briefly stated, the system comprises a four-sided frame having an infrared transparent bezel along the inside thereof and having infrared emitters along the top and one side of the frame with infrared detectors along the sides opposite the emitters. Darlington transitor arrays are used as source and sink drivers for driving the LED's in an array. The I/O lines of a microprocessor in conjunction with the source and sink drivers are used to selectively energize each LED. Additional I/O lines of the microprocessor in conjunction with BCD decoders are used to selectively energize corresponding infrared detecting phototransistors before, during and after LED turn-on. A host computer supplies a clocking signal for the microprocessor with programming in the microprocessor thereby automatically performing the selection and deselection of emitters and detectors. A serial data stream is outputted from the microprocessor which indicates to the host computer the location of any broken light beams thereby indicating a stylus hit.

    Abstract translation: 教导了红外触摸输入系统。 简而言之，该系统包括四边框架，其四周框架具有沿着其内部的红外透明边框，并且沿着框架的顶部和一侧具有红外发射器，其具有沿着与发射器相对的侧面的红外探测器。 达林顿滤波器阵列用作驱动LED阵列的源极和吸收驱动器。 微处理器与源和宿驱动器的I / O线用于选择性地激励每个LED。 微处理器的附加I / O线与BCD解码器结合使用，可以在LED开启之前，期间和之后选择性地激励相应的红外检测光电晶体管。 主计算机为微处理器提供时钟信号，在微处理器中编程，从而自动执行发射器和检测器的选择和取消选择。 从微处理器输出串行数据流，其向主计算机指示任何破碎的光束的位置，从而指示触针被击中。

    Nucleic acid sequences encoding Conus protein disulfide isomerase
    9.
    发明授权
    Nucleic acid sequences encoding Conus protein disulfide isomerase 有权
    编码Conus蛋白二硫键异构酶的核酸序列

    公开(公告)号：US07238513B2

    公开(公告)日：2007-07-03

    申请号：US11216937

    申请日：2005-08-31

    Applicant: Grzegorz Bulaj ,  Baldomero M. Olivera ,  Olga Buczek ,  James E. Garrett ,  Ian Goodsell

    Inventor： Grzegorz Bulaj ,  Baldomero M. Olivera ,  Olga Buczek ,  James E. Garrett ,  Ian Goodsell

    IPC: C12N9/00 ,  C12N9/90 ,  C07H21/04 ,  C12P21/06

    CPC classification number: C07H21/04 ,  C12N9/90 ,  C12Y503/04001

    Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.

    Abstract translation: 蛋白二硫键异构酶是Conus毒液管的主要成分。 本发明涉及来自Conus蜗牛的蛋白质二硫键异构酶（PDI），编码康科斯蛋白二硫键异构酶的核酸序列，以及使用蛋白质二硫键异构酶折叠富含二硫键的肽的方法。 通过PDI催化的芋螺毒素前体的氧化折叠更有效，并且减少了瞬时积累的折叠物质的数量和浓度。 脯氨酸的PDI辅助氧化折叠也受到前肽相对于成熟肽的影响。

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