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    Device for tissue condition measurement
    1.
    发明授权
    Device for tissue condition measurement 有权

    公开(公告)号：US10980478B2

    公开(公告)日：2021-04-20

    申请号：US15781868

    申请日：2016-12-20

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Shrutin Ulman ,  Sindhu Priyadarshini Nellur Prakash ,  Ratheesh Narayanan ,  Shashidharan Arputha

    IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455

    Abstract: Peripheral oedema causes a swelling of the legs of a patient due to an abnormal accumulation of fluids in the interstitium of the patient. Oedema is directly related to heart diseases, kidney and liver problems and pathological conditions. As such, is a useful indicator of a person's overall health. Oedema is typically assessed by a subjective manual test administered by a medical professional. As such, an objective assessment of oedema is often difficult to make. The present disclosure concerns a device for tissue condition measurement. The device enables an objective assessment of oedema to be made, by providing to a medical professional, or a medical ancillary worker, with information useful to judge the presence of oedema. This is achieved by performing a photoacoustic analysis of biological components present in the tissue, and then by performing a physical test by advancing a blunt instrument onto the area suspected of oedema, withdraw blunt instrument, and then assessing the depth and/or rebound characteristics of the pit.

    METHOD AND APPARATUS FOR SEPARATING PLASMA FROM BLOOD FOR BILIRUBIN LEVEL ESTIMATION
    2.
    发明申请
    METHOD AND APPARATUS FOR SEPARATING PLASMA FROM BLOOD FOR BILIRUBIN LEVEL ESTIMATION 审中-公开
    用于从血液分离等离子体水平估计的方法和装置

    公开(公告)号：US20150185233A1

    公开(公告)日：2015-07-02

    申请号：US14418497

    申请日：2013-07-17

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Anil Shivram Raiker ,  Ravindra Bhat ,  Shrutin Ulman

    IPC: G01N33/72 ,  G01N1/28 ,  G01N21/05 ,  A61B5/15 ,  G01N21/25

    CPC classification number: G01N33/728 ,  A61B5/150022 ,  A61B5/150343 ,  A61B5/150755 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0481 ,  G01N1/28 ,  G01N21/05 ,  G01N21/25 ,  G01N33/491 ,  G01N2201/02 ,  G01N2201/061

    Abstract: The present disclosure pertains to a system for separating plasma and/or serum from blood. The system is configured to separate plasma and/or serum from between about 20 and about 50 μl of blood. Separating plasma and/or serum from that amount of blood may be useful during a bilirubin level estimation in newborn babies. The system alleviates the need to centrifuge a sample of blood to separate the blood plasma and/or serum. The system is configured such that the separated serum is held by the system during an optical analysis to estimate bilirubin levels, thus eliminating the need to transfer the serum sample to a cuvette for analysis. In some embodiments, the system comprises a cartridge body, a filter, a serum pathway, an analysis port, a negative pressure source, a suction connector port, and/or other components.

    Abstract translation: 本公开涉及用于从血液中分离血浆和/或血清的系统。 该系统被配置为将血浆和/或血清从约20至约50μl的血液分离。 在新生婴儿的胆红素水平估计中，将血浆和/或血清与该量的血液分离可能是有用的。 该系统减轻了离心血液样品以分离血浆和/或血清的需要。 该系统被配置为使得分离的血清在光学分析期间由系统保持以估计胆红素水平，因此不需要将血清样品转移到比色皿进行分析。 在一些实施例中，该系统包括筒体，过滤器，血清通路，分析端口，负压源，吸入连接器端口和/或其他部件。

    Identifying an optimal image from a number of ultrasound images
    4.
    发明授权
    Identifying an optimal image from a number of ultrasound images 有权

    公开(公告)号：US12004901B2

    公开(公告)日：2024-06-11

    申请号：US17257656

    申请日：2019-07-05

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Shrutin Ulman ,  Navaneetha Krishnan Santhana Naidu ,  Girish Krishnamurthy

    IPC: A61B8/08 ,  A61B8/00 ,  G06T5/40 ,  G06T7/00 ,  G16H30/20 ,  G16H50/30

    CPC classification number: A61B8/0866 ,  A61B8/4236 ,  A61B8/5292 ,  G06T5/40 ,  G06T7/0014 ,  G16H30/20 ,  G16H50/30 ,  G06T2207/10132 ,  G06T2207/30044

    Abstract: The invention relates to a method of identifying, from a number of ultrasound images (34) acquired during an ultrasound examination of a subject (6), the ultrasound image best suited to analyze a pre-determined anatomical structure of the subject. The method comprises the steps of (a) Providing a number of ultrasound images (34) acquired during an ultrasound examination of the subject; (b) Deriving at least one biometric parameter (96) related to the anatomical structure from a physical examination of the subject, (c) Retrieving a reference image (38) showing a target view of the anatomical structure (35); (d) For each of the number of ultrasound images (34), calculating an image similarity index between the ultrasound image and the reference image, (e) For at least the ultrasound image(s) having the best image similarity index, determining (100) a biometric parameter from the ultrasound image, and calculating a biometric similarity index, i.e. a measure of the agreement between the biometric parameter, as determined from the ultrasound image, and the corresponding biometric parameter as derived from the physical examination; and (f) selecting the optimal ultrasound image based on the biometric similarity index, and optionally on the image similarity index.

    IDENTIFYING AN OPTIMAL IMAGE FROM A NUMBER OF ULTRASOUND IMAGES
    5.
    发明申请
    IDENTIFYING AN OPTIMAL IMAGE FROM A NUMBER OF ULTRASOUND IMAGES 有权

    公开(公告)号：US20210267570A1

    公开(公告)日：2021-09-02

    申请号：US17257656

    申请日：2019-07-05

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Shrutin Ulman ,  Navaneetha Krishnan Santhana Naidu ,  Girish Krishnamurthy

    IPC: A61B8/08 ,  A61B8/00 ,  G16H50/30 ,  G16H30/20 ,  G06T7/00 ,  G06T5/40

    Abstract: The invention relates to a method of identifying, from a number of ultrasound images (34) acquired during an ultrasound examination of a subject (6), the ultrasound image best suited to analyze a pre-determined anatomical structure of the subject. The method comprises the steps of (a) Providing a number of ultrasound images (34) acquired during an ultrasound examination of the subject; (b) Deriving at least one biometric parameter (96) related to the anatomical structure from a physical examination of the subject, (c) Retrieving a reference image (38) showing a target view of the anatomical structure (35); (d) For each of the number of ultrasound images (34), calculating an image similarity index between the ultrasound image and the reference image, (e) For at least the ultrasound image(s) having the best image similarity index, determining (100) a biometric parameter from the ultrasound image, and calculating a biometric similarity index, i.e. a measure of the agreement between the biometric parameter, as determined from the ultrasound image, and the corresponding biometric parameter as derived from the physical examination; and (f) selecting the optimal ultrasound image based on the biometric similarity index, and optionally on the image similarity index.

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