公开(公告)号：US20180133362A1

公开(公告)日：2018-05-17

申请号：US15809022

申请日：2017-11-10

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Young-Min KIM ,  ChangHo KIM

IPC: A61L26/00 ,  C08G79/025 ,  A61L24/04

CPC classification number: A61L26/0014 ,  A61L24/046 ,  A61L2400/04 ,  C08G79/025 ,  C08L85/02

Abstract: The present invention relates to a phosphazene-based polymer comprising an amino acid ester, polyethylene glycol, a group comprising a functional group, and a catechol group linked directly or by a linker to a part of or an entire functional group, in a predetermined ratio. In addition, the present invention relates to a preparation method thereof, and a tissue-adhesive composition comprising the same as an active ingredient.

公开(公告)号：US20230219251A1

公开(公告)日：2023-07-13

申请号：US17707975

申请日：2022-03-30

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jinqyu KIM ,  Jae-Gwan PARK ,  Kyung Tae HONG ,  Soo Chang SONG ,  Jin Gu KANG

IPC: B27K3/16 ,  A01N59/14 ,  A01P17/00 ,  A01P3/00

CPC classification number: B27K3/163 ,  A01N59/14 ,  A01P17/00 ,  A01P3/00 ,  B27K2240/20 ,  B27K2240/30

Abstract: The present invention relates to a multifunctional wood preservative composition containing a compound prepared by reaction of hydrazine hydrate and boric acid and to a method for wood preservation treatment using the same.
The wood preservative composition of the present invention can not only impart flame retardant, insect-repellent, rot-resistant, insect-repellent, and rust-proof effects to wood, such as various wooden structures including wooden cultural assets, but also causes no whitening and makes relatively fewer color changes for dancheong. Furthermore, the wood preservative composition of the present invention is provided as a one-component type liquid and thus can save time and costs for wood treatment and is convenient to use.

公开(公告)号：US20250163223A1

公开(公告)日：2025-05-22

申请号：US19019853

申请日：2025-01-14

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Ki Hyun HONG

IPC: C08G79/025 ,  A61K9/50 ,  A61K38/04 ,  A61K45/06 ,  C08J3/075 ,  C08J3/20 ,  C08J3/24

Abstract: Provided is a hydrogel composition including thermosensitive poly(phosphazene) to which a plurality of hydrophobic amino acids, hydrophilic polymers, and host molecules are substituted; and a physiologically active material linked to a guest molecule, wherein the poly(phosphazene) and the physiologically active material form a conjugate by inclusion of the guest molecule in the host molecule via a host-guest interaction.

公开(公告)号：US20210163691A1

公开(公告)日：2021-06-03

申请号：US16986507

申请日：2020-08-06

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Bo-Bae SEO

IPC: C08G79/025 ,  B33Y70/10 ,  A61L27/18 ,  A61L27/52 ,  B33Y80/00

Abstract: The present invention relates to a thermosensitive hydrogel composition, which while comprising an amino acid ester, polyethylene glycol, and a functional group for the introduction of a functional moiety at an end thereof at a predetermined ratio, comprises a polyphosphazene-based polymer having a controlled length and a content of polyethylene glycol contained therein, in which a reversible sol-gel transition character is altered; a medical polymer hydrogel comprising the polyphosphazene-based polymer; or an ink composition for 3D printing.

公开(公告)号：US20210009763A1

公开(公告)日：2021-01-14

申请号：US16906028

申请日：2020-06-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Ki Hyun HONG

IPC: C08G79/025 ,  C08J3/075 ,  C08J3/20 ,  C08J3/24 ,  A61K38/04 ,  A61K9/50

Abstract: Provided is a hydrogel composition including thermosensitive poly(phosphazene) to which a plurality of hydrophobic amino acids, hydrophilic polymers, and host molecules are substituted; and a physiologically active material linked to a guest molecule, wherein the poly(phosphazene) and the physiologically active material form a conjugate by inclusion of the guest molecule in the host molecule via a host-guest interaction.

公开(公告)号：US20200085860A1

公开(公告)日：2020-03-19

申请号：US16567027

申请日：2019-09-11

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Soo Chang SONG ,  Young-min KIM

IPC: A61K31/80 ,  A61P25/00

Abstract: The present disclosure relates to a pharmaceutical composition for preventing or treating spinal cord injury comprising an imidazole-poly(organophosphazene) hydrogel or a pharmaceutically acceptable salt thereof, a method for preventing or treating spinal cord injury, and a food composition for preventing or ameliorating spinal cord injury.The imidazole-poly(organophosphazene) hydrogel of the present disclosure has the effect of regenerating the extracellular matrix (ECM) by filling cystic cavities and can thus be effectively used for the prevention and treatment of spinal cord injury by a simple injection method.