公开(公告)号：US09365866B2

公开(公告)日：2016-06-14

申请号：US13292953

申请日：2011-11-09

Applicant: Mahito Nakanishi ,  Ken Nishimura ,  Masayuki Sano ,  Manami Ohtaka

Inventor： Mahito Nakanishi ,  Ken Nishimura ,  Masayuki Sano ,  Manami Ohtaka

IPC: C12N15/63 ,  C12N7/01 ,  C12N15/864 ,  C12N5/0789 ,  C12N15/86 ,  C12N5/074 ,  C12N15/113 ,  C12N15/877

CPC classification number: C12N15/86 ,  C12N5/0696 ,  C12N15/1131 ,  C12N15/8775 ,  C12N15/8776 ,  C12N2310/14 ,  C12N2501/602 ,  C12N2501/603 ,  C12N2501/604 ,  C12N2501/606 ,  C12N2510/00 ,  C12N2760/18843

Abstract: A reprogramming gene-loaded Sendai viral vector comprising Sendai virus genes and reprogramming genes, wherein the Sendai virus genes include an NP gene, P/C gene, M gene, F gene, HN gene and L gene, wherein each of the M gene, the F gene and the FIN gene is from a Sendai virus strain Cl.151-derived gene and wherein at least one of the M gene, the F gene and the HN gene is functionally deleted and the L gene encodes the amino-acid sequence of the L protein in which the amino-acid residue at position 1618 is valine and a method of producing the same.

Abstract translation: 包含仙台病毒基因和重编程基因的重编程基因载体仙台病毒载体，其中仙台病毒基因包括NP基因，P / C基因，M基因，F基因，HN基因和L基因，其中M基因， F基因和FIN基因来自仙台病毒株Cl.151衍生的基因，其中M基因，F基因和HN基因中的至少一个在功能上被缺失，并且L基因编码氨基酸序列 1618位氨基酸残基为缬氨酸的L蛋白及其制备方法。

公开(公告)号：US09145564B2

公开(公告)日：2015-09-29

申请号：US12595497

申请日：2008-04-11

Applicant: Ken Nishimura ,  Hiroaki Segawa ,  Mahito Nakanishi

Inventor： Ken Nishimura ,  Hiroaki Segawa ,  Mahito Nakanishi

IPC: C12N15/00 ,  C07H21/02 ,  C12N7/01 ,  A61K39/12 ,  A61K39/155 ,  A01N63/00 ,  C12N15/86 ,  A61K38/16 ,  C12N7/00 ,  A61K35/12 ,  A61K35/13

CPC classification number: C12N15/86 ,  A61K35/12 ,  A61K35/13 ,  A61K38/162 ,  C12N7/00 ,  C12N2760/18821 ,  C12N2760/18843

Abstract: A persistently infective virus vector is produced by using a gene so modified as to encode an amino acid sequence including a valine substituted for an amino acid residue at position-1618 in the amino acid sequence for an L protein of a persistently non-infective Sendai virus. A non-transmissible, persistently infective virus vector is also produced by defecting or deleting at least one of M gene, F gene, and HN gene. These virus vectors have no cytotoxicity, can achieve the sustained gene expression over a long period of time, is safe, and is therefore useful.

Abstract translation: 通过使用如此修饰的基因来编码持续感染性病毒载体，以编码氨基酸序列，所述氨基酸序列包括取代氨基酸序列中位置1618处的氨基酸残基的氨基酸序列，用于持续非感染性仙台病毒的L蛋白 。 通过缺失或缺失M基因，F基因和HN基因中的至少一个也产生不可传播的持续感染性病毒载体。 这些病毒载体没有细胞毒性，可以长时间达到持续的基因表达，是安全的，因此是有用的。

公开(公告)号：US20070113681A1

公开(公告)日：2007-05-24

申请号：US11286193

申请日：2005-11-22

Applicant: Ken Nishimura ,  Ian Hardcastle

Inventor： Ken Nishimura ,  Ian Hardcastle

IPC: G01D7/00

CPC classification number: G06F3/0414

Abstract: A spatial pressure distribution sensor comprises a sensor array and a processor. The sensor array comprises an array of pressure sensors. Each of the pressure sensors is operable to generate a respective pressure signal in response to pressure applied to it. The pressure signal quantifies the pressure with greater than single-bit resolution. The processor is operable in response to the pressure signals to generate an information signal representing the spatial distribution of pressure applied to the sensor array.

Abstract translation: 空间压力分布传感器包括传感器阵列和处理器。 传感器阵列包括压力传感器阵列。 每个压力传感器可操作以响应于施加到其上的压力产生相应的压力信号。 压力信号以大于单位分辨率量化压力。 处理器响应于压力信号而可操作以产生表示施加到传感器阵列的压力的空间分布的信息信号。

公开(公告)号：US20070058707A1

公开(公告)日：2007-03-15

申请号：US11226974

申请日：2005-09-15

Applicant: William Trutna ,  Steven Rosenau ,  Ken Nishimura ,  Graham Flower ,  Richard Ruby ,  Michael Frank ,  Mark Unkrich

Inventor： William Trutna ,  Steven Rosenau ,  Ken Nishimura ,  Graham Flower ,  Richard Ruby ,  Michael Frank ,  Mark Unkrich

IPC: H04B17/00

CPC classification number: H04W72/02 ,  H04W72/085

Abstract: Systems and methods of detecting wireless channel status from acoustic discrimination of spectral content are described. In one aspect, a wireless system includes a spectrum analyzer, a detector, and a controller. The spectrum analyzer is operable to acoustically discriminate spectral content of an input electrical signal in multiple discrete frequency channels. The detector is operable to determine respective statuses of the frequency channels from the acoustically discriminated spectral content. The controller is operable to select one of the frequency channels based on the determined statuses of the frequency channels.

Abstract translation: 描述了从频谱内容的声学鉴别中检测无线信道状态的系统和方法。 一方面，无线系统包括频谱分析仪，检测器和控制器。 频谱分析仪可用于在多个离散频道中声学地区分输入电信号的频谱含量。 检测器可操作以从声学鉴别的频谱内容确定频道的各自状态。 控制器可操作以基于所确定的频率信道的状态来选择一个频率信道。

公开(公告)号：US07106512B2

公开(公告)日：2006-09-12

申请号：US11255502

申请日：2005-10-21

Applicant: Rene Helbing ,  Charles D. Hoke ,  Ken Nishimura

Inventor： Rene Helbing ,  Charles D. Hoke ,  Ken Nishimura

IPC: G02B5/18 ,  G02B27/44

CPC classification number: G02F1/31 ,  H04Q11/0005 ,  H04Q2011/0026 ,  H04Q2011/0035

Abstract: A wavelength selective switching device and method for selectively transmitting optical signals based on wavelength utilizes diffraction to spatially separate the optical signals of different wavelengths such that the optical signal of a selected wavelength can be selectively transmitted. The wavelength selective switching device selectively rotates the polarization components of the optical signals such that the polarization states of the polarization components are the same in both incoming and outgoing directions at the diffraction grating. Thus, a diffraction grating with a high grating line frequency (e.g. greater than 900 grating lines per mm for signals in the 1550 nm wavelength range) can be used for diffracting the polarization components of the optical signals in both the incoming and outgoing directions.

Abstract translation: 用于基于波长选择性地发射光信号的波长选择性开关装置和方法利用衍射来空间分离不同波长的光信号，使得可以选择性地发射所选波长的光信号。 波长选择开关器件选择性地旋转光信号的偏振分量，使得偏振分量的偏振状态在衍射光栅的入射方向和出射方向都相同。 因此，可以使用具有高光栅线频率（例如，对于1550nm波长范围内的信号来说，每毫米大于900个光栅线数）的衍射光栅来衍射光信号在入射和出射方向上的偏振分量。

公开(公告)号：US20060167731A1

公开(公告)日：2006-07-27

申请号：US11044342

申请日：2005-01-27

Applicant: Ken Nishimura ,  Ian Hardcastle

Inventor： Ken Nishimura ,  Ian Hardcastle

IPC: G05B19/418

CPC classification number: G06Q10/109 ,  G06Q10/06314 ,  G06Q10/1095

Abstract: Methods, machines, and machine-readable media storing machine-readable instructions for automatically scheduling meetings are described. In one aspect, a meeting request is received. The meeting request specifies a meeting duration, a set of non-fungible resources, and a number of required fungible resources of a specified type. A potential-meeting-time set of timeslots is determined. The potential-meeting-time set corresponding to a union of a first set of timeslots during each of which at least some of the non-fungible resources are available and a second set of timeslots corresponding to an intersection of each timeslot during which at least the specified number of fungible resources of the specified type are available. At least one timeslot having a duration at least as long as the specified meeting duration is identified in the potential-meeting-time set.

Abstract translation: 描述了存储用于自动安排会议的机器可读指令的方法，机器和机器可读介质。 一方面，接收会议请求。 会议请求规定会议期限，一组不可替代资源和指定类型的所需可替代资源的数量。 确定一个潜在会议时间的一组时隙。 所述潜在会议时间集合对应于其中至少一些非可替代资源可用的第一组时隙的并集，以及对应于每个时隙的交集的第二组时隙，其中至少 指定数量的可指定类型的可替代资源可用。 在潜在会议时间集合中识别至少一个具有至少等于指定的会议持续时间的持续时间的时隙。

公开(公告)号：US20060077552A1

公开(公告)日：2006-04-13

申请号：US11255502

申请日：2005-10-20

Applicant: Rene Helbing ,  Charles Hoke ,  Ken Nishimura

Inventor： Rene Helbing ,  Charles Hoke ,  Ken Nishimura

IPC: G02B5/18 ,  G02B27/44

CPC classification number: G02F1/31 ,  H04Q11/0005 ,  H04Q2011/0026 ,  H04Q2011/0035

Abstract: A wavelength selective switching device and method for selectively transmitting optical signals based on wavelength utilizes diffraction to spatially separate the optical signals of different wavelengths such that the optical signal of a selected wavelength can be selectively transmitted. The wavelength selective switching device selectively rotates the polarization components of the optical signals such that the polarization states of the polarization components are the same in both incoming and outgoing directions at the diffraction grating. Thus, a diffraction grating with a high grating line frequency (e.g. greater than 900 grating lines per mm for signals in the 1550 nm wavelength range) can be used for diffracting the polarization components of the optical signals in both the incoming and outgoing directions.

公开(公告)号：US20060054776A1

公开(公告)日：2006-03-16

申请号：US10938998

申请日：2004-09-10

Applicant: Ken Nishimura

Inventor： Ken Nishimura

IPC: H01J40/14

CPC classification number: H05B33/0869 ,  H05B37/0272

Abstract: In one embodiment, ones of a plurality of drive currents are modulated in accordance with ones of a plurality of unique modulation sequences. The modulated drive currents are then applied to a plurality of light emitters. Thereafter, a stream of optical measurements is obtained from a photosensor that is positioned to sense the aggregate light emitted by the light emitters. The stream of optical measurements is then correlated with the modulation sequences to extract optical responses to each of the plurality of drive currents. Finally, each drive current is regulated based on its relationship to its corresponding optical response. Related apparatus, and other methods for regulating the drive currents of a plurality of light emitters, is also disclosed.

Abstract translation: 在一个实施例中，根据多个唯一调制序列中的一个调制多个驱动电流中的一个。 然后将调制的驱动电流施加到多个发光体。 此后，从位于感测由发光体发射的聚集光的光传感器获得光学测量流。 然后将光学测量流与调制序列相关联，以提取对多个驱动电流中的每一个的光学响应。 最后，根据其对应的光学响应的​​关系来调节每个驱动电流。 还公开了用于调节多个发光体的驱动电流的相关装置和其它方法。

公开(公告)号：US20060035152A1

公开(公告)日：2006-02-16

申请号：US10540867

申请日：2003-12-09

Applicant: Ken Nishimura ,  Naoto Arai ,  Toru Oshima ,  Fumio Daio ,  Munehisa Ikoma ,  Norio Saito ,  Hideo Kaiya

Inventor： Ken Nishimura ,  Naoto Arai ,  Toru Oshima ,  Fumio Daio ,  Munehisa Ikoma ,  Norio Saito ,  Hideo Kaiya

IPC: H01M4/64 ,  H01M2/16

CPC classification number: H01M4/13 ,  H01M2/0207 ,  H01M2/022 ,  H01M2/34 ,  H01M4/66 ,  H01M4/667 ,  H01M4/70 ,  H01M10/0431 ,  H01M10/0436 ,  H01M10/0525 ,  H01M10/0587

Abstract: An electrochemical device having an electrode plate assembly. The electrode plate assembly includes (a) at least one first electrode, (b) at least one second electrode, and (c) a separator interposed between the first electrode and the second electrode. The first electrode includes a first current collector sheet and at least one first electrode mixture layer carried thereon. The second electrode includes a second current collector sheet and at least one second electrode mixture layer carried thereon. At least one of the first current collector sheet and the second current collector sheet has a conductive area and an insulating area.

Abstract translation: 具有电极板组件的电化学装置。 电极板组件包括（a）至少一个第一电极，（b）至少一个第二电极，和（c）介于第一电极和第二电极之间的隔膜。 第一电极包括第一集电体片和在其上承载的至少一个第一电极混合物层。 第二电极包括第二集电体片和在其上承载的至少一个第二电极混合物层。 第一集电体片和第二集电体片中的至少一个具有导电区域和绝缘区域。

公开(公告)号：US06760551B2

公开(公告)日：2004-07-06

申请号：US10283566

申请日：2002-10-29

Applicant: Adrian Wan-Chew Seet ,  Ken Nishimura ,  Richard C. Walker

Inventor： Adrian Wan-Chew Seet ,  Ken Nishimura ,  Richard C. Walker

IPC: H04B1006

CPC classification number: H04L25/063

Abstract: The present invention is a decoder for decoding a signal. The decoder includes a discriminator and a threshold generator. The discriminator receives the signal and generates an output voltage equal to a first voltage if the signal is less than a threshold level that is input to the discriminator and equal to a second voltage if the signal is greater than the threshold level. The threshold level depends on the output from the discriminator in a preceding time interval that depends on the impulse response of a transmission link through which the input signal has passed. The threshold generator implements a low-pass analog filter that receives the output voltage during each of the clock periods and generates therefrom a filtered output signal.

Abstract translation: 本发明是用于对信号进行解码的解码器。 解码器包括鉴别器和阈值发生器。 如果信号小于输入到鉴频器的阈值电平，并且如果信号大于阈值电平，鉴别器接收信号并产生等于第一电压的输出电压，并等于第二电压。 门限电平取决于取决于输入信号已通过的传输链路的脉冲响应的前一时间间隔内来自鉴别器的输出。 阈值发生器实现低通模拟滤波器，其在每个时钟周期期间接收输出电压，并从其产生滤波后的输出信号。