公开(公告)号：US3980717A

公开(公告)日：1976-09-14

申请号：US158594

申请日：1971-06-30

Applicant: Lee A. Subluskey

Inventor： Lee A. Subluskey

IPC: C07C201/16 ,  C07C79/26

CPC classification number: C07C201/16 ,  C07C201/08

Abstract: Process for the manufacture of para-nitro-meta-cresol in high yield from directly available and inexpensive meta/para-cresol mixtures, without need heretofore for first resolving the cresol mixture to provide a separate meta-cresol reactant.The process comprises subjecting the cresol mixture to nitration, whereby para-nitro-meta-cresol is formed, and then separating the para-nitro-meta-cresol from the resulting nitration reaction mixture.In one embodiment, the cresol mixture is introduced into reaction with an aqueous acid mixture containing HNO.sub.3 and HNO.sub.2 as the only acid ingredients, under defined critical conditions of feed flow rate, temperature, acid concentrations, and reactant proportions to provide the cresol nitration reaction product mixture.

Abstract translation: 从直接可利用的和便宜的间/对甲酚混合物中高产率地制备对硝基间甲酚的方法，而无需首先拆分甲酚混合物以提供单独的间甲酚反应物。