公开(公告)号：US20050272995A1

公开(公告)日：2005-12-08

申请号：US11186328

申请日：2005-07-21

Applicant: Martin Prince

Inventor： Martin Prince

IPC: A61B5/05 ,  A61B5/055 ,  A61B8/00 ,  A61B8/08 ,  G01R33/567

CPC classification number: A61B5/416 ,  A61B5/055 ,  A61B5/7285 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/488 ,  G01R33/5673

Abstract: An MRI system includes an ultrasonic detector system that includes an ultrasonic transducer placed to detect movement of selected anatomic structure in a patient. The transducer signal is analyzed to produce a gating signal which is used by the MRI system to trigger data acquisition.

Abstract translation: MRI系统包括超声波检测器系统，其包括放置以检测患者中所选择的解剖结构的移动的超声换能器。 分析传感器信号以产生由MRI系统用于触发数据采集的门控信号。

公开(公告)号：US20050203377A1

公开(公告)日：2005-09-15

申请号：US11108417

申请日：2005-04-18

Applicant: Richard Watts ,  Yi Wang ,  Martin Prince

Inventor： Richard Watts ,  Yi Wang ,  Martin Prince

IPC: A61B5/055 ,  G01R33/28 ,  A61B5/05

CPC classification number: G01R33/5601 ,  A61B5/055

Abstract: Current bolus chase magnetic resonance angiography is limited by the imaging time for each station. Tailoring the density of k-space sampling along the anterior-posterior direction of the coronal station allows a substantial decrease in scan time that leads to greater contrast bolus sharing among stations and consequently a significant improvement in image quality. Fast arterial-venous transit in the carotid arteries requires accurate, reliable timing of the acquisition to the bolus transit to maximize arterial signal and minimize venous artifacts. The rising edge of the bolus is not utilized in conventional elliptical-centric view ordering because the critical k-space center must be acquired with full arterial enhancement. The invention provides a recessed elliptical-centric view ordering scheme is introduced in which the k-space center is acquired a few seconds following scan initiation. The recessed view ordering is shown to be more robust to timing errors in a patient studies.

Abstract translation: 目前的推注磁共振血管造影受每个站的成像时间的限制。 沿着冠状站的前后方向调整k空间采样的密度允许扫描时间的显着减少，导致站之间更大的对比度推注共享，并且因此显着改善图像质量。 在颈动脉中的快速动脉 - 静脉转运需要准确，可靠的采集到推注转运的时间，以最大化动脉信号并使静脉伪影最小化。 在常规的以椭圆为中心的视图排序中，推注的上升边缘不被利用，因为必须以完全动脉增强获得临界k空间中心。 本发明提供了一种以椭圆为中心的视图排序方案，其中在扫描开始后几秒钟内获取k空间中心。 凹陷视图排序显示出对患者研究中的定时误差更为鲁棒。

公开(公告)号：US20050119557A1

公开(公告)日：2005-06-02

申请号：US11003101

申请日：2004-12-03

Applicant: James Meaney ,  Martin Prince

Inventor： James Meaney ,  Martin Prince

IPC: A61B5/055 ,  A61B5/05

CPC classification number: A61B5/055 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56383 ,  G06F19/00

Abstract: The present invention is a technique of, and system for, imaging vascular anatomy over distance considerably greater than the maximum practical field of view of a magnetic resonance imaging system while using substantially one contrast agent injection. The technique and system of the present invention acquires image data of a plurality of image volumes which are representative of different portions of the patient's body. The image data of each image volume includes image data which is representative of the center of k-space. The acquisition of image data which is representative of the center of k-space is correlated with a concentration of contrast agent in the artery(ies) residing in the image volume being substantially greater than the concentration of contrast agent in veins and background tissue adjacent to the artery(ies). This provides preferential enhancement of arteries relative to adjacent veins and background tissue for each acquisition, wherein each acquisition is representative of a different portion of the arterial system (e.g., abdominal aorta, femoral, popliteal, and tibial arteries).

Abstract translation: 本发明是一种技术，并且用于在使用基本上一个造影剂注射的情况下远远超过磁共振成像系统的最大实际视野来对血管解剖结构进行成像的技术和系统。 本发明的技术和系统获取代表患者身体的不同部分的多个图像体积的图像数据。 每个图像体积的图像数据包括表示k空间中心的图像数据。 代表k空间中心的图像数据的获取与静止在图像体积中的动脉中的造影剂的浓度基本上大于静脉和邻近的静脉和背景组织中造影剂的浓度相关 动脉。 这提供了相对于每个采集的相邻静脉和背景组织的动脉的优先增强，其中每个采集代表动脉系统的不同部分（例如，腹主动脉，股骨，po骨和胫骨动脉）。

公开(公告)号：US5346488A

公开(公告)日：1994-09-13

申请号：US844243

申请日：1992-03-02

Applicant: Martin Prince ,  Allan Oseroff ,  John A. Parrish

Inventor： Martin Prince ,  Allan Oseroff ,  John A. Parrish

IPC: A61B17/00 ,  A61B17/22 ,  A61B18/20 ,  A61B18/24 ,  G02B6/42 ,  A61N5/06

CPC classification number: A61B18/20 ,  A61B18/245 ,  G02B6/4214 ,  G02B6/4296 ,  A61B2017/00154 ,  A61B2017/22085 ,  A61B2017/22087 ,  A61B2018/00636

Abstract: A method of ablating atherosclerotic plaque by means of short-duration laser light pulses. A carotenoid, such as beta-carotene, is preferably administered to the patient by injection or ingestion prior to exposing the plaque with laser light. Research data obtained by analysis of the absorption characteristics of plaque and the healthy arterial tissue reveals that the plaque may be selectively ablated without damaging the surrounding normal tissue by illuminating the plaque with laser light having a wavelength of about 430 to about 510 nanometers such that the relative absorption coefficient exhibited by the plaque is more than 1.5 times the absorption coefficient of the arterial tissue. Short duration laser light pulses preferably illuminate the plaque for less than the thermal relaxation time of the volume of exposed material. The intensity of the laser light is preferably in the range from about 1 to about 9 joules/cm.sup.2 in order to ablate the plaque without endangering the surrounding tissue. The carotenoid administered to the patient enhances the absorption coefficient of the plaque to facilitate ablation and additionally facilitates the detection of the plaque.

Abstract translation: 一种通过短时间激光脉冲消融动脉粥样硬化斑块的方法。 在用激光暴露斑块之前，优选通过注射或摄取向患者施用类胡萝卜素，例如β-胡萝卜素。 通过分析斑块和健康动脉组织的吸收特征获得的研究数据显示，通过用波长为约430至约510纳米的激光照射斑块，可以选择性地烧蚀斑块而不损伤周围正常组织，使得 斑块表现的相对吸收系数是动脉组织吸收系数的1.5倍以上。 短持续时间的激光脉冲优选照射斑块以小于暴露材料的体积的热松弛时间。 激光的强度优选在约1至约9焦耳/ cm 2的范围内，以便消融斑块而不危及周围组织。 施用于患者的类胡萝卜素增强斑块的吸收系数以促进消融，并且另外促进斑块的检测。

公开(公告)号：US20060264741A1

公开(公告)日：2006-11-23

申请号：US11493055

申请日：2006-07-26

Applicant: Martin Prince

Inventor： Martin Prince

IPC: A61B5/05

CPC classification number: A61K49/18 ,  A61B5/02007 ,  A61B5/055 ,  A61B5/201 ,  A61B5/416 ,  A61B5/7285 ,  G01R33/281 ,  G01R33/5619 ,  G01R33/563 ,  G01R33/56308

Abstract: The present invention is a technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.

公开(公告)号：US20060167492A1

公开(公告)日：2006-07-27

申请号：US11331519

申请日：2006-01-13

Applicant: Martin Prince

Inventor： Martin Prince

IPC: A61B17/00

CPC classification number: A61B17/135 ,  A61B5/055 ,  A61B17/1322 ,  A61B17/1355 ,  A61B2090/374

Abstract: There are many inventions described herein as well as many aspects and embodiments of those inventions. A thigh compression device and technique to control, time, delay and/or prevent excessive early venous enhancement relative to arterial enhancement and thereby improve and/or enhance MRA images, including peripheral MRA images. In one embodiment, the present invention uses a curved strip of material which is longer on the superior edge and shorter along the inferior edge. When wrapped around the conical or conal-like shape of the thigh of a subject (for example, a human), the thigh compression device more uniformly conforms to and/or fits around the thigh, providing more even/uniform compression as well as reducing, minimizing and/or eliminating significant movement of the thigh compression device towards the knees of the subject. Notably, a snug fit on the thighs may also enable the thigh compression device to be inflated with less fluid (for example, air) which is faster and less cumbersome for the operator.

Abstract translation: 这里描述了许多发明以及这些发明的许多方面和实施例。 一种大腿压缩装置和技术，用于相对于动脉增强来控制，时间，延迟和/或预防过度的早期静脉增强，从而改善和/或增强MRA图像，包括外围MRA图像。 在一个实施例中，本发明使用弯曲的材料条，其在上边缘上较长并且沿着下边缘较短。 当围绕受试者（例如人）的大腿的锥形或锥形形状缠绕时，大腿压缩装置更均匀地适应和/或适合大腿周围，提供更均匀/均匀的压缩以及减少 ，最大限度地减少和/或消除大腿压缩装置朝向受试者的膝盖的显着运动。 值得注意的是，大腿上的紧贴配合还可以使得较少的流体（例如，空气）使大腿压缩装置膨胀，这对于操作者而言更快且不那么麻烦。

公开(公告)号：US5035269A

公开(公告)日：1991-07-30

申请号：US305908

申请日：1989-02-03

Applicant: Frank G. Pytryga ,  Martin Prince

Inventor： Frank G. Pytryga ,  Martin Prince

IPC: F17C13/08 ,  F17C13/12

CPC classification number: F17C13/123 ,  F17C13/085 ,  F17C2201/0109 ,  F17C2201/0119 ,  F17C2201/056 ,  F17C2201/058 ,  F17C2205/0111 ,  F17C2205/0161 ,  F17C2205/018 ,  F17C2205/0196 ,  F17C2270/0745

Abstract: A safety gas and liquid containment unit is provided with sealing for retaining the hazardous gas therein until treated. The containment unit can be placed on a transport carrier and rotated from a vertical position to a horizontal position thereon. The gas cylinder may be brought to the containment unit by placing it on a wheeled cart. By aligning the cart with the horizontally positioned containment unit, the container is then transferred from the cart to the containment unit, which can in turn be transported to an appropriate area for treatment. Upon removal of the toxic or other gases, the container can be withdrawn from the containment unit by a winch mechanism.

Abstract translation: 安全气体和液体容纳单元设置有用于将有害气体保持在其中的密封件，直到被处理。 容纳单元可以放置在运输托架上并从其垂直位置旋转到水平位置。 气瓶可以通过将其放置在带轮的推车上而被带到容纳单元。 通过将推车与水平定位的容纳单元对准，容器然后从推车转移到容纳单元，该容器单元又可运输到适当的区域进行处理。 在去除有毒或其它气体时，容器可以通过绞盘机构从容纳单元中取出。

公开(公告)号：US4802515A

公开(公告)日：1989-02-07

申请号：US933160

申请日：1986-11-21

Applicant: Frank G. Pytryga ,  Martin Prince

Inventor： Frank G. Pytryga ,  Martin Prince

IPC: F17C13/08 ,  F17C13/12 ,  B65B21/00

CPC classification number: F17C13/085 ,  F17C13/123 ,  F17C2201/0109 ,  F17C2201/0119 ,  F17C2201/056 ,  F17C2201/058 ,  F17C2205/0111 ,  F17C2205/0161 ,  F17C2205/018 ,  F17C2205/0196 ,  F17C2270/0745

Abstract: A safety gas and liquid containment unit is provided with sealing for retaining the hazardous gas therein until treated. The containment unit can be placed on a transport carrier and rotated from a vertical position to a horizontal position thereon. The gas cylinder may be brought to the containment unit by placing it on a wheeled cart. By aligning the cart with the horizontally positioned containment unit, the container is then transferred from the cart to the containment unit, which can in turn be transported to an appropriate area for treatment. Upon removal of the toxic or other gases, the container can be withdrawn from the containment unit by a winch mechanism.

Abstract translation: 安全气体和液体容纳单元设置有用于将有害气体保持在其中的密封件，直到被处理。 容纳单元可以放置在运输托架上并从其垂直位置旋转到水平位置。 气瓶可以通过将其放置在带轮的推车上而被带到容纳单元。 通过将推车与水平定位的容纳单元对准，容器然后从推车转移到容纳单元，该容器单元又可运输到适当的区域进行处理。 在去除有毒或其它气体时，容器可以通过绞盘机构从容纳单元中取出。