Abstract:
A process of forming a non-optically detectable authentication marking (210,320, 410,535) in a diamond (200,300). Authentication marking (210,320,410,535) is formed adjacent the outer surface of an article formed from a diamond material having intrinsic optical centers. Method includes the step of applying an image of predesigned authentication marking(210,320,410,535) to a region (201,310,530) of a diamond (200,300) at or adjacent the surface of the diamond (200,300) by way of a direct laser writing; wherein the fluorescence background of the diamond material from intrinsic optical center is suppressed by authentication marking(210,320, 410, 535) under fluorescent imaging, such that the non-optically detectable identifiable authentication marking (210,320,410,535) is viewable against the fluorescence background at the region (201,310,530) of the diamond (200,300) where the authentication marking (210,320,410,535) is applied.
Abstract:
A process of forming a non-optically detectable authentication marking (110), includes the step of: applying a marking at a surface of a diamond (200) using a focused ion beam (FIB) writing process so as to provide a non-optically detectable authentication marking (110) which is formed by alteration in the optical characteristics of a portion of the diamond material at the outer surface of the diamond to form a marked portion; wherein the marking is optically invisible, and wherein the marking is viewable by an imaging method which provides an observable contrast between the portion of the diamond having altered optical characteristics and the non-marked portion of the diamond. The marking process can assist in the prevention of the counterfeiting of precious articles, and be of assistance in the incident of theft. A marking, a diamond, a process of viewing a marking on a diamond are further disclosed.
Abstract:
A system (300) for providing a three-dimensional computer tomography image of a gemstone, the system (300) comprising an X-ray source (330) for providing an X-ray towards a gemstone (320); an X-ray detector system for detecting X-rays transmitted through or diffracted by the gemstone (320). The X-ray detector system surrounds the gemstone (320) and detects a three-dimensional multi-angle X-ray diffraction pattern from the gemstone (320) upon rotation of the gemstone (320) within the X-ray field, and provides an output signal therefrom, wherein the output signal provides for invasive three-dimension multiangle X-ray diffraction reconstructed computed tomography from the three-dimension multiangle X-ray diffraction pattern.
Abstract:
A process for enhancing polarization of 13C for subsequence MRI imaging, the process comprising providing a suspension consisting of a first plurality of particulates having NV centers and a second plurality of particulates for providing internal reflection of light with wavelength for the excitement of NV centers and 13C; and applying light, magnetic field and microwave to said suspension, such that the NV centers are polarized and such that the electron spins of the VN centres are transferred to 13C atoms upon the Rabi frequency of the NV centres matching the Larmor frequency of 13C; wherein the particulates of the second plurality reflect and transmit the light through the suspension such that said light is distributed through said suspension.
Abstract:
An identifiable mark on a portion of a polished facet of a surface of an article and being identifiable by an optical magnifying viewing device, said identifiable mark comprising a nano-structure formed by a two-dimensional or a three-dimensional lattice of a plurality of discrete nanometer sized recessed or protruded entities, wherein said entities are arranged within a predefined region of said polished facet in a predetermined arrangement in relation to each other and such that an outer interface surface between the facet of the article and air is formed and an inner interface surface between the facet of the article and air is formed. Said predetermined arrangement of said entities is non-uniform and non-periodic arrangement, and wherein said entities are sized and shaped so as to cause optical scattering upon reflection of incident light and the distance from the inner interface surface to the outer interface surface is greater than the amplitude of the non-marked portion of said polished face. Upon reflection of incident light having one or more predetermined wavelengths by said lattice at a predetermined angle of incidence to said lattice, interference due to scattering of light from said lattice is induced such that said reflected light has a variation in intensity providing one or more local maxima of one or more wavelengths. Said mark is identifiable by way of an optical magnifying viewing device inclined at a requisite viewing angle such that a local maxima is detected.
Abstract:
A conjugate (110) comprising a nanoparticle (210) for delivery of a drug to a treatment site in the body of a subject; a drug molecule (220) releasably linked to said nanoparticle (210), wherein said drug molecule (220) has a therapeutic effect at the treatment site in the body of the subject; and a disease targeting molecule (230) releasably linked to said nanoparticle (210); wherein upon said conjugate (110) being adjacent diseased tissue (240) of a subject, said disease targeting molecule (230) retains the conjugate (110) adjacent said diseased tissue (240); said drug molecule (220) is released from said nanoparticle (110) so as to provide a therapeutic effect to said diseased tissue (240); and said disease targeting molecule (230) is subsequently released from said nanoparticle (210) such that retention of the nanoparticle (210) is released, and such that the nanoparticle (210) is dispersible from said diseased tissue (240).
Abstract:
A device(100a(i), 100a(ii), 100a(iii), 100a(iv), 200 for cis-tracing polarization of 12C isotope-based magnetic resource imaging contrast agents, comprising one or more diamond material structures(120(i), 120(ii), 120(iii), 120(iv), 210, 220) and one or more channels(105a(i), 105a (ii), 105a (iii), 105a (iv), 205) provided adjacent to the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220); the diamond material structures 120(i), 120(ii), 120(iii), 120(iv), 210, 220) provide a source of negatively charged nitrogen vacancy celles for polarization of a 13C iso-type-based magnetic measure imaging contrast agesi disguised in one or more channels(105a (i), 105a (ii), 105a (iii), 105a (iv), 205) and cis diamond material structure(120(i), 120(ii), 120(iii), 120(iv), 210, 220) provides a light guide for light for excitation of nitrogen vacancy celles for polarization of 13C isotope-based magnetic resource imaging contrast agent.
Abstract:
A topically administrable moisturising composition for moisturising the skin of a subject, said moisturising composition comprising (i) a plurality of conjugates wherein each conjugate is comprised of a nanodiamond and a plurality of water molecules, and (ii) a carrier media for topical administration.
Abstract:
A method of distinguishing cancerous cells and healthy cells of a subject from each other comprises the steps: (i) contacting a region of tissue of a subject suspected of including at least some cancer cells with a plurality of nanodiamonds, wherein the plurality of nanodiamonds comprise a first plurality of conjugates, wherein the conjugates of the first plurality of conjugates consist of first nanodiamonds and one or more cancer cell targeting agents, wherein the first nanodiamonds have a first type of colour center, and a second plurality of conjugates, wherein the conjugates of the second plurality of conjugates consist of second nanodiamonds and one or more healthy cell targeting agents, wherein the second nanodiamonds have a second type of colour center; and (ii) applying light of a first wavelength so as to excite the first type of colour center and applying light of a second wavelength so as to excite the second type of colour center, wherein upon contacting the region of tissue with the plurality of nanodiamonds, cancer cells are adhered to the first plurality of conjugates, and healthy cells are adhered to the second plurality of conjugates; wherein upon applying light to the region of tissue, the colour centers of the nanodiamonds of the first plurality of conjugates adhered to cancer cells emit fluorescence at a first wavelength, and the colour centers of the nanodiamonds of the second plurality of conjugates adhered to healthy cells emit fluorescence at a second wavelength; and wherein the colour contrast between the two wavelengths and the positions of respective conjugates delineate the area of cancer cells and the area of healthy cells from each other.