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公开(公告)号：US20200078215A1
公开(公告)日：2020-03-12
申请号：US16315499
申请日：2017-07-05
Applicant: MicroOptx Inc. , J. David BROWN , Christopher Clark PULLING , Roy Christian MARTIN , Edward Aaron COHEN
Abstract: Devices can be implanted in an eye to treat glaucoma and/or dry eye. The devices described herein include a body defining a lumen and having first and second ends and external and lumenal surfaces. The body has a length sufficient to provide fluid communication between the anterior chamber and tear film of the eye through the lumen when the device is implanted in the sclera. The body can include a radiused distal edge. A distal end portion of the body can be laterally flared. The body can include a mid-body portion that is laterally narrower than distal and proximal end portions of the body. Methods of treating glaucoma and/or dry eye, wherein the device is implanted in the sclera of an afflicted eye, are also described.
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公开(公告)号：US20220125638A1
公开(公告)日：2022-04-28
申请号：US17569929
申请日：2022-01-06
Applicant: MicroOptx Inc.
Abstract: Devices can be implanted in an eye to treat glaucoma and/or dry eye. The devices described herein include a body defining a lumen and having first and second ends and external and lumenal surfaces. The body has a length sufficient to provide fluid communication between the anterior chamber and tear film of the eye through the lumen when the device is implanted in the sclera. The body can include a radiused distal edge. A distal end portion of the body can be laterally flared. The body can include a mid-body portion that is laterally narrower than distal and proximal end portions of the body. Methods of treating glaucoma and/or dry eye, wherein the device is implanted in the sclera of an afflicted eye, are also described.
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公开(公告)号：US11291391B2
公开(公告)日：2022-04-05
申请号：US16209010
申请日：2018-12-04
Applicant: MicroOptx Inc.
Inventor： Edward Aaron Cohen , Roy Christian Martin
Abstract: Monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. In some implantable device embodiments, the device includes a polymer layer comprising a material that changes volume in response to varying glucose concentrations of the aqueous humor. A pressure sensor in the device can detect the changes in volume. In some implantable device embodiments, the device includes electrodes for determining the glucose concentration.
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Patent Agency Ranking
公开(公告)号：US11039954B2
公开(公告)日：2021-06-22
申请号：US16360777
申请日：2019-03-21
Applicant: MicroOptx Inc.
Inventor： Edward Aaron Cohen , Daniel Charles Voce
Abstract: An implantable ocular drug delivery system can include inserting an implantable device into an eye, where the device contains therapeutics intended to be released for local or systemic effects. In some implantable device embodiments, the device includes a microchannel intended to reduce intraocular pressure. In some implantable device embodiments, the device includes a microchannel intended to treat dry eye.
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公开(公告)号：US20210079178A1
公开(公告)日：2021-03-18
申请号：US17105111
申请日：2020-11-25
Applicant: MicroOptx Inc.
Inventor： Tingrui Pan , Edward Aaron Cohen , Ben Bazor , Gaomai Yang
IPC: C08J5/12 , C08J7/18 , C08G81/00 , B81C3/00 , C08J7/16 , C08F290/14 , C08J7/12 , C09J5/00 , B81C1/00 , C08G81/02
Abstract: Some polymeric devices, as described herein, can be made of a first layer and a second layer bonded together with one or more microfluidic channels defined internal to the device. The first layer and the second layer may each include a substrate and a polymer bonded to the substrate. The two layers may be bonded through a polymer network that interpenetrates the polymers in the first and second layers. This disclosure also describes methods of bonding together polymeric articles. The methods include diffusing polymerizable monomers and radical forming initiators into the surfaces of one or both of the polymers, putting the surfaces into contact, and initiating polymerization to create a polymer network that interpenetrates the polymers.
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公开(公告)号：US20200297530A1
公开(公告)日：2020-09-24
申请号：US16360777
申请日：2019-03-21
Applicant: MicroOptx Inc.
Inventor： Edward Aaron Cohen , Daniel Charles Voce
IPC: A61F9/00 , A61F9/007 , A61K31/573 , A61K9/00
Abstract: An implantable ocular drug delivery system can include inserting an implantable device into an eye, where the device contains therapeutics intended to be released for local or systemic effects. In some implantable device embodiments, the device includes a microchannel intended to reduce intraocular pressure. In some implantable device embodiments, the device includes a microchannel intended to treat dry eye.
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公开(公告)号：US20190185629A1
公开(公告)日：2019-06-20
申请号：US16323481
申请日：2017-08-03
Applicant: MicroOptx Inc.
Inventor： Tingrui Pan , Edward Aaron Cohen , Ben Bazor , Gaomai Yang
CPC classification number: C08J5/128 , B81C1/00071 , B81C3/001 , B81C2201/034 , B81C2203/036 , C08F265/00 , C08F265/02 , C08F265/04 , C08F287/00 , C08F291/00 , C08F293/00 , C08G81/027 , C08J7/123 , C08J7/16 , C08J7/18 , C08J2367/02 , C08J2433/14 , C08J2433/16
Abstract: Some polymeric devices, as described herein, can be made of a first layer and a second layer bonded together with one or more microfluidic channels defined internal to the device. The first layer and the second layer may each include a substrate and a polymer bonded to the substrate. The two layers may be bonded through a polymer network that interpenetrates the polymers in the first and second layers. This disclosure also describes methods of bonding together polymeric articles. The methods include diffusing polymerizable monomers and radical forming initiators into the surfaces of one or both of the polymers, putting the surfaces into contact, and initiating polymerization to create a polymer network that interpenetrates the polymers.
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公开(公告)号：US20190175083A1
公开(公告)日：2019-06-13
申请号：US16209010
申请日：2018-12-04
Applicant: MicroOptx Inc.
Inventor： Edward Aaron Cohen , Roy Christian Martin
Abstract: Monitoring glucose concentration in aqueous humor can include inserting an implantable device into an eye and determining glucose concentration as a function of glucose sensed at the implantable device. In some implantable device embodiments, the device includes a polymer layer comprising a material that changes volume in response to varying glucose concentrations of the aqueous humor. A pressure sensor in the device can detect the changes in volume. In some implantable device embodiments, the device includes electrodes for determining the glucose concentration.
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