公开(公告)号：US3951953A

公开(公告)日：1976-04-20

申请号：US486713

申请日：1974-07-08

Applicant: Mohammad Zafar Khan

Inventor： Mohammad Zafar Khan

IPC: C07D499/21 ,  A61K9/16 ,  A61K31/43 ,  A61K47/48 ,  B01J41/04 ,  C07D499/04 ,  C07D499/22 ,  C07D499/44 ,  C08F8/00 ,  C08F8/34 ,  C07D499/68 ,  C07D499/70

CPC classification number: A61K47/48184 ,  A61K31/43 ,  Y10S514/96

Abstract: Complexes of a semi-synthetic penicillin and an anion exchange resin cross-linked less than 4% and wherein the penicillin, with or without a non-complexed additional penicillin, is absorbed onto and in the ducts or channels in the resin particles substantially all of which have diameters between 20 .mu. and 250 .mu.. The semi-synthetic penicillin constitutes 35-65% of the complex. The complexes are formulated as pharmaceutical compositions which can be in tablet or syrup form. The penicillin is released rapidly and completely and is free of unpleasant taste.

Abstract translation: 半合成青霉素和阴离子交换树脂交联的复合物小于4％，其中青霉素（有或没有非络合的另外的青霉素）被吸收到树脂颗粒中的管道或通道上，基本上全部被吸收 直径在20〜250亩之间。 半合成青霉素占复合物的35-65％。 络合物配制成可以是片剂或糖浆形式的药物组合物。 青霉素快速，完全释放，没有不愉快的味道。